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Results: 1 to 20 of 157

1.

Proinflammatory role of stem cells in abdominal aortic aneurysms.

Ryer EJ, Garvin RP, Schworer CM, Bernard-Eckroth KR, Tromp G, Franklin DP, Elmore JR, Kuivaniemi H.

J Vasc Surg. 2014 Jul 2. pii: S0741-5214(14)00934-3. doi: 10.1016/j.jvs.2014.04.067. [Epub ahead of print]

PMID:
24997808
[PubMed - as supplied by publisher]
2.

eMERGEing progress in genomics-the first seven years.

Crawford DC, Crosslin DR, Tromp G, Kullo IJ, Kuivaniemi H, Hayes MG, Denny JC, Bush WS, Haines JL, Roden DM, McCarty CA, Jarvik GP, Ritchie MD.

Front Genet. 2014 Jun 17;5:184. doi: 10.3389/fgene.2014.00184. eCollection 2014. Review.

PMID:
24987407
[PubMed]
Free PMC Article
3.

Design patterns for the development of electronic health record-driven phenotype extraction algorithms.

Rasmussen LV, Thompson WK, Pacheco JA, Kho AN, Carrell DS, Pathak J, Peissig PL, Tromp G, Denny JC, Starren JB.

J Biomed Inform. 2014 Jun 21. pii: S1532-0464(14)00145-2. doi: 10.1016/j.jbi.2014.06.007. [Epub ahead of print]

PMID:
24960203
[PubMed - as supplied by publisher]
4.

Genetic-based prediction of disease traits: prediction is very difficult, especially about the future(†).

Schrodi SJ, Mukherjee S, Shan Y, Tromp G, Sninsky JJ, Callear AP, Carter TC, Ye Z, Haines JL, Brilliant MH, Crane PK, Smelser DT, Elston RC, Weeks DE.

Front Genet. 2014 Jun 2;5:162. doi: 10.3389/fgene.2014.00162. eCollection 2014. Review.

PMID:
24917882
[PubMed]
Free PMC Article
5.

Update on abdominal aortic aneurysm research: from clinical to genetic studies.

Kuivaniemi H, Ryer EJ, Elmore JR, Hinterseher I, Smelser DT, Tromp G.

Scientifica (Cairo). 2014;2014:564734. doi: 10.1155/2014/564734. Epub 2014 Apr 17. Review.

PMID:
24834361
[PubMed]
Free PMC Article
6.

A rigorous algorithm to detect and clean inaccurate adult height records within EHR systems.

Muthalagu A, Pacheco JA, Aufox S, Peissig PL, Fuehrer JT, Tromp G, Kho AN, Rasmussen-Torvik LJ.

Appl Clin Inform. 2014 Feb 19;5(1):118-26. doi: 10.4338/ACI-2013-09-RA-0074. eCollection 2014.

PMID:
24734128
[PubMed - in process]
7.

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, Dechene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D Jr, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzy Ski P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, Macarthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, Deluca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovre I L, Palanda I A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM.

Genome Biol. 2014 Mar 25;15(3):R53. [Epub ahead of print]

PMID:
24667040
[PubMed - as supplied by publisher]
Free PMC Article
8.

Family members of patients with abdominal aortic aneurysms are at increased risk for aneurysms: analysis of 618 probands and their families from the Liège AAA Family Study.

Sakalihasan N, Defraigne JO, Kerstenne MA, Cheramy-Bien JP, Smelser DT, Tromp G, Kuivaniemi H.

Ann Vasc Surg. 2014 May;28(4):787-97. doi: 10.1016/j.avsg.2013.11.005. Epub 2013 Dec 21.

PMID:
24365082
[PubMed - in process]
9.

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.

Mosley JD, Van Driest SL, Larkin EK, Weeke PE, Witte JS, Wells QS, Karnes JH, Guo Y, Bastarache L, Olson LM, McCarty CA, Pacheco JA, Jarvik GP, Carrell DS, Larson EB, Crosslin DR, Kullo IJ, Tromp G, Kuivaniemi H, Carey DJ, Ritchie MD, Denny JC, Roden DM.

PLoS One. 2013 Dec 12;8(12):e81503. doi: 10.1371/journal.pone.0081503. eCollection 2013.

PMID:
24349080
[PubMed - in process]
Free PMC Article
10.

MicroRNA analysis in placentas from patients with preeclampsia: comparison of new and published results.

Betoni JS, Derr K, Pahl MC, Rogers L, Muller CL, Packard RE, Carey DJ, Kuivaniemi H, Tromp G.

Hypertens Pregnancy. 2013 Nov;32(4):321-39. doi: 10.3109/10641955.2013.807819. Epub 2013 Jul 11. Review.

PMID:
23844600
[PubMed - indexed for MEDLINE]
11.

The Electronic Medical Records and Genomics (eMERGE) Network: past, present, and future.

Gottesman O, Kuivaniemi H, Tromp G, Faucett WA, Li R, Manolio TA, Sanderson SC, Kannry J, Zinberg R, Basford MA, Brilliant M, Carey DJ, Chisholm RL, Chute CG, Connolly JJ, Crosslin D, Denny JC, Gallego CJ, Haines JL, Hakonarson H, Harley J, Jarvik GP, Kohane I, Kullo IJ, Larson EB, McCarty C, Ritchie MD, Roden DM, Smith ME, Böttinger EP, Williams MS; eMERGE Network.

Genet Med. 2013 Oct;15(10):761-71. doi: 10.1038/gim.2013.72. Epub 2013 Jun 6. Review.

PMID:
23743551
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

A sequence variant associated with sortilin-1 (SORT1) on 1p13.3 is independently associated with abdominal aortic aneurysm.

Jones GT, Bown MJ, Gretarsdottir S, Romaine SP, Helgadottir A, Yu G, Tromp G, Norman PE, Jin C, Baas AF, Blankensteijn JD, Kullo IJ, Phillips LV, Williams MJ, Topless R, Merriman TR, Vasudevan TM, Lewis DR, Blair RD, Hill AA, Sayers RD, Powell JT, Deloukas P, Thorleifsson G, Matthiasson SE, Thorsteinsdottir U, Golledge J, Ariëns RA, Johnson A, Sohrabi S, Scott DJ, Carey DJ, Erdman R, Elmore JR, Kuivaniemi H, Samani NJ, Stefansson K, van Rij AM.

Hum Mol Genet. 2013 Jul 15;22(14):2941-7. doi: 10.1093/hmg/ddt141. Epub 2013 Mar 27.

PMID:
23535823
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Identification, basic characterization and evolutionary analysis of differentially spliced mRNA isoforms of human YAP1 gene.

Gaffney CJ, Oka T, Mazack V, Hilman D, Gat U, Muramatsu T, Inazawa J, Golden A, Carey DJ, Farooq A, Tromp G, Sudol M.

Gene. 2012 Nov 10;509(2):215-22. doi: 10.1016/j.gene.2012.08.025. Epub 2012 Aug 24.

PMID:
22939869
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

Helgadottir A, Gretarsdottir S, Thorleifsson G, Holm H, Patel RS, Gudnason T, Jones GT, van Rij AM, Eapen DJ, Baas AF, Tregouet DA, Morange PE, Emmerich J, Lindblad B, Gottsäter A, Kiemeny LA, Lindholt JS, Sakalihasan N, Ferrell RE, Carey DJ, Elmore JR, Tsao PS, Grarup N, Jørgensen T, Witte DR, Hansen T, Pedersen O, Pola R, Gaetani E, Magnadottir HB, Wijmenga C, Tromp G, Ronkainen A, Ruigrok YM, Blankensteijn JD, Mueller T, Wells PS, Corral J, Soria JM, Souto JC, Peden JF, Jalilzadeh S, Mayosi BM, Keavney B, Strawbridge RJ, Sabater-Lleal M, Gertow K, Baldassarre D, Nyyssönen K, Rauramaa R, Smit AJ, Mannarino E, Giral P, Tremoli E, de Faire U, Humphries SE, Hamsten A, Haraldsdottir V, Olafsson I, Magnusson MK, Samani NJ, Levey AI, Markus HS, Kostulas K, Dichgans M, Berger K, Kuhlenbäumer G, Ringelstein EB, Stoll M, Seedorf U, Rothwell PM, Powell JT, Kuivaniemi H, Onundarson PT, Valdimarsson E, Matthiasson SE, Gudbjartsson DF, Thorgeirsson G, Quyyumi AA, Watkins H, Farrall M, Thorsteinsdottir U, Stefansson K.

J Am Coll Cardiol. 2012 Aug 21;60(8):722-9. doi: 10.1016/j.jacc.2012.01.078.

PMID:
22898070
[PubMed - indexed for MEDLINE]
Free Article
15.

Novel pathways in the pathobiology of human abdominal aortic aneurysms.

Hinterseher I, Erdman R, Elmore JR, Stahl E, Pahl MC, Derr K, Golden A, Lillvis JH, Cindric MC, Jackson K, Bowen WD, Schworer CM, Chernousov MA, Franklin DP, Gray JL, Garvin RP, Gatalica Z, Carey DJ, Tromp G, Kuivaniemi H.

Pathobiology. 2013;80(1):1-10. doi: 10.1159/000339303. Epub 2012 Jul 12.

PMID:
22797469
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

MicroRNA expression signature in human abdominal aortic aneurysms.

Pahl MC, Derr K, Gäbel G, Hinterseher I, Elmore JR, Schworer CM, Peeler TC, Franklin DP, Gray JL, Carey DJ, Tromp G, Kuivaniemi H.

BMC Med Genomics. 2012 Jun 15;5:25. doi: 10.1186/1755-8794-5-25.

PMID:
22704053
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Presence of Borrelia burgdorferi sensu lato antibodies in the serum of patients with abdominal aortic aneurysms.

Hinterseher I, Gäbel G, Corvinus F, Lück C, Saeger HD, Bergert H, Tromp G, Kuivaniemi H.

Eur J Clin Microbiol Infect Dis. 2012 May;31(5):781-9. doi: 10.1007/s10096-011-1375-y. Epub 2011 Aug 13.

PMID:
21842293
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Regional expression of HOXA4 along the aorta and its potential role in human abdominal aortic aneurysms.

Lillvis JH, Erdman R, Schworer CM, Golden A, Derr K, Gatalica Z, Cox LA, Shen J, Vander Heide RS, Lenk GM, Hlavaty L, Li L, Elmore JR, Franklin DP, Gray JL, Garvin RP, Carey DJ, Lancaster WD, Tromp G, Kuivaniemi H.

BMC Physiol. 2011 May 31;11:9. doi: 10.1186/1472-6793-11-9.

PMID:
21627813
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Role of complement cascade in abdominal aortic aneurysms.

Hinterseher I, Erdman R, Donoso LA, Vrabec TR, Schworer CM, Lillvis JH, Boddy AM, Derr K, Golden A, Bowen WD, Gatalica Z, Tapinos N, Elmore JR, Franklin DP, Gray JL, Garvin RP, Gerhard GS, Carey DJ, Tromp G, Kuivaniemi H.

Arterioscler Thromb Vasc Biol. 2011 Jul;31(7):1653-60. doi: 10.1161/ATVBAHA.111.227652. Epub 2011 Apr 14.

PMID:
21493888
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Upregulated signaling pathways in ruptured human saccular intracranial aneurysm wall: an emerging regulative role of Toll-like receptor signaling and nuclear factor-κB, hypoxia-inducible factor-1A, and ETS transcription factors.

Kurki MI, Häkkinen SK, Frösen J, Tulamo R, von und zu Fraunberg M, Wong G, Tromp G, Niemelä M, Hernesniemi J, Jääskeläinen JE, Ylä-Herttuala S.

Neurosurgery. 2011 Jun;68(6):1667-75; discussion 1675-6. doi: 10.1227/NEU.0b013e318210f001.

PMID:
21336216
[PubMed - indexed for MEDLINE]

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