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Results: 1 to 20 of 146

1.

Endothelin receptor blockade ameliorates vascular fragility in endothelial cell-specific Fli1 knockout mice by increasing Fli1 DNA-binding ability.

Akamata K, Asano Y, Yamashita T, Noda S, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Trojanowska M, Sato S.

Arthritis Rheumatol. 2015 Feb 23. doi: 10.1002/art.39062. [Epub ahead of print]

PMID:
25707716
2.

Simultaneous downregulation of KLF5 and Fli1 is a key feature underlying systemic sclerosis.

Noda S, Asano Y, Nishimura S, Taniguchi T, Fujiu K, Manabe I, Nakamura K, Yamashita T, Saigusa R, Akamata K, Takahashi T, Ichimura Y, Toyama T, Tsuruta D, Trojanowska M, Nagai R, Sato S.

Nat Commun. 2014 Dec 12;5:5797. doi: 10.1038/ncomms6797.

PMID:
25504335
4.

Fibrosis, vascular activation, and immune abnormalities resembling systemic sclerosis in bleomycin-treated fli-1-haploinsufficient mice.

Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, Toyama T, Trojanowska M, Sato S.

Arthritis Rheumatol. 2015 Feb;67(2):517-26. doi: 10.1002/art.38948.

5.

MMP-12 deficiency attenuates angiotensin II-induced vascular injury, M2 macrophage accumulation, and skin and heart fibrosis.

Stawski L, Haines P, Fine A, Rudnicka L, Trojanowska M.

PLoS One. 2014 Oct 10;9(10):e109763. doi: 10.1371/journal.pone.0109763. eCollection 2014.

6.

Endoplasmic reticulum stress and endothelial dysfunction.

Lenna S, Han R, Trojanowska M.

IUBMB Life. 2014 Aug;66(8):530-7. doi: 10.1002/iub.1292. Epub 2014 Aug 11.

PMID:
25130181
7.

Decreased interleukin-20 expression in scleroderma skin contributes to cutaneous fibrosis.

Kudo H, Jinnin M, Asano Y, Trojanowska M, Nakayama W, Inoue K, Honda N, Kajihara I, Makino K, Fukushima S, Ihn H.

Arthritis Rheumatol. 2014 Jun;66(6):1636-47. doi: 10.1002/art.38380.

PMID:
24470401
8.

Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis.

van Bon L, Affandi AJ, Broen J, Christmann RB, Marijnissen RJ, Stawski L, Farina GA, Stifano G, Mathes AL, Cossu M, York M, Collins C, Wenink M, Huijbens R, Hesselstrand R, Saxne T, DiMarzio M, Wuttge D, Agarwal SK, Reveille JD, Assassi S, Mayes M, Deng Y, Drenth JP, de Graaf J, den Heijer M, Kallenberg CG, Bijl M, Loof A, van den Berg WB, Joosten LA, Smith V, de Keyser F, Scorza R, Lunardi C, van Riel PL, Vonk M, van Heerde W, Meller S, Homey B, Beretta L, Roest M, Trojanowska M, Lafyatis R, Radstake TR.

N Engl J Med. 2014 Jan 30;370(5):433-43. doi: 10.1056/NEJMoa1114576. Epub 2013 Dec 18.

9.

Epstein-Barr virus infection induces aberrant TLR activation pathway and fibroblast-myofibroblast conversion in scleroderma.

Farina A, Cirone M, York M, Lenna S, Padilla C, McLaughlin S, Faggioni A, Lafyatis R, Trojanowska M, Farina GA.

J Invest Dermatol. 2014 Apr;134(4):954-64. doi: 10.1038/jid.2013.423. Epub 2013 Oct 11.

10.

Fli1 represses transcription of the human α2(I) collagen gene by recruitment of the HDAC1/p300 complex.

Asano Y, Trojanowska M.

PLoS One. 2013 Sep 13;8(9):e74930. doi: 10.1371/journal.pone.0074930. eCollection 2013.

11.

Endothelial cells recruit macrophages and contribute to a fibrotic milieu in bleomycin lung injury.

Leach HG, Chrobak I, Han R, Trojanowska M.

Am J Respir Cell Mol Biol. 2013 Dec;49(6):1093-101. doi: 10.1165/rcmb.2013-0152OC.

12.

Adenosine A(2A) receptors promote collagen production by a Fli1- and CTGF-mediated mechanism.

Chan ES, Liu H, Fernandez P, Luna A, Perez-Aso M, Bujor AM, Trojanowska M, Cronstein BN.

Arthritis Res Ther. 2013;15(3):R58.

13.

Endothelial GATA-6 deficiency promotes pulmonary arterial hypertension.

Ghatnekar A, Chrobak I, Reese C, Stawski L, Seta F, Wirrig E, Paez-Cortez J, Markiewicz M, Asano Y, Harley R, Silver R, Feghali-Bostwick C, Trojanowska M.

Am J Pathol. 2013 Jun;182(6):2391-406. doi: 10.1016/j.ajpath.2013.02.039. Epub 2013 Apr 11.

14.

HLA-B35 and dsRNA induce endothelin-1 via activation of ATF4 in human microvascular endothelial cells.

Lenna S, Chrobak I, Farina GA, Rodriguez-Pascual F, Lamas S, Lafyatis R, Scorza R, Trojanowska M.

PLoS One. 2013;8(2):e56123. doi: 10.1371/journal.pone.0056123. Epub 2013 Feb 18.

15.

Increased expression of endoplasmic reticulum stress and unfolded protein response genes in peripheral blood mononuclear cells from patients with limited cutaneous systemic sclerosis and pulmonary arterial hypertension.

Lenna S, Farina AG, Martyanov V, Christmann RB, Wood TA, Farber HW, Scorza R, Whitfield ML, Lafyatis R, Trojanowska M.

Arthritis Rheum. 2013 May;65(5):1357-66. doi: 10.1002/art.37891.

16.
17.

Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1.

Bujor AM, Haines P, Padilla C, Christmann RB, Junie M, Sampaio-Barros PD, Lafyatis R, Trojanowska M.

Int J Mol Med. 2012 Dec;30(6):1473-80. doi: 10.3892/ijmm.2012.1150. Epub 2012 Oct 5.

18.

The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis.

Lenna S, Trojanowska M.

Curr Opin Rheumatol. 2012 Nov;24(6):663-8. Review.

19.

Angiotensin II induces skin fibrosis: a novel mouse model of dermal fibrosis.

Stawski L, Han R, Bujor AM, Trojanowska M.

Arthritis Res Ther. 2012 Aug 22;14(4):R194. doi: 10.1186/ar4028.

20.

A role for estrogen receptor-α and estrogen receptor-β in collagen biosynthesis in mouse skin.

Markiewicz M, Znoyko S, Stawski L, Ghatnekar A, Gilkeson G, Trojanowska M.

J Invest Dermatol. 2013 Jan;133(1):120-7. doi: 10.1038/jid.2012.264. Epub 2012 Aug 16.

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