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Transplanted olfactory ensheathing cells reduce retinal degeneration in Royal College of Surgeons rats.
Huo SJ, Li YC, Xie J, Li Y, Raisman G, Zeng YX, He JR, Weng CH, Yin ZQ. Huo SJ, et al. Curr Eye Res. 2012 Aug;37(8):749-58. doi: 10.3109/02713683.2012.697972. Epub 2012 Jun 12. Curr Eye Res. 2012. PMID: 22691022 Free article.
PURPOSE OF THE STUDY: Retinitis pigmentosa (RP) is a group of genetic disorders and a slow loss of vision that is caused by a cascade of retinal degenerative events. We examined whether these retinal degenerative events were reduced after cultured mixtures of …
PURPOSE OF THE STUDY: Retinitis pigmentosa (RP) is a group of genetic disorders and a slow loss of vision that is caused by a cascade of …
Transplanted olfactory ensheathing cells reduce the gliotic injury response of Muller cells in a rat model of retinitis pigmentosa.
Huo SJ, Li Y, Raisman G, Yin ZQ. Huo SJ, et al. Brain Res. 2011 Mar 25;1382:238-44. doi: 10.1016/j.brainres.2010.12.079. Epub 2011 Jan 6. Brain Res. 2011. PMID: 21215725
We now report that cultured syngeneic adult rat olfactory ensheathing cells transplanted into the subretinal space of pigmented Royal College of Surgeon rats survived for a minimum of 8weeks, migrated into surrounding space, …
We now report that cultured syngeneic adult rat olfactory ensheathing cells transplanted into the subretinal spa …
Olfactory Ensheathing Cells Grafted Into the Retina of RCS Rats Suppress Inflammation by Down-Regulating the JAK/STAT Pathway.
Xie J, Li Y, Dai J, He Y, Sun D, Dai C, Xu H, Yin ZQ. Xie J, et al. Front Cell Neurosci. 2019 Jul 25;13:341. doi: 10.3389/fncel.2019.00341. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31402855 Free PMC article.
However, mechanisms by which grafted OECs can reduce degeneration in the retina are not well understood. In the present study, we set up an in vitro OEC/BV2 microglia co-culture system, and an in vivo royal college of surgeons (RCS) rat model, u …
However, mechanisms by which grafted OECs can reduce degeneration in the retina are not well understood. In the present study, …