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Results: 1 to 20 of 108

1.

Measurement of the acute metabolic response to hypoxia in rat tumours in vivo using magnetic resonance spectroscopy and hyperpolarised pyruvate.

Bluff JE, Reynolds S, Metcalf S, Alizadeh T, Kazan SM, Bucur A, Wholey EG, Bibby BA, Williams L, Paley MN, Tozer GM.

Radiother Oncol. 2015 Mar 27. pii: S0167-8140(15)00148-6. doi: 10.1016/j.radonc.2015.03.011. [Epub ahead of print]

2.

Relaxation and exchange dynamics of hyperpolarized 129 Xe in human blood.

Norquay G, Leung G, Stewart NJ, Tozer GM, Wolber J, Wild JM.

Magn Reson Med. 2014 Aug 28. doi: 10.1002/mrm.25417. [Epub ahead of print]

PMID:
25168398
3.

Tumour cells expressing single VEGF isoforms display distinct growth, survival and migration characteristics.

Kanthou C, Dachs GU, Lefley DV, Steele AJ, Coralli-Foxon C, Harris S, Greco O, Dos Santos SA, Reyes-Aldasoro CC, English WR, Tozer GM.

PLoS One. 2014 Aug 13;9(8):e104015. doi: 10.1371/journal.pone.0104015. eCollection 2014.

4.

An in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate.

Williams LJ, Mukherjee D, Fisher M, Reyes-Aldasoro CC, Akerman S, Kanthou C, Tozer GM.

Br J Pharmacol. 2014 Nov;171(21):4902-13. doi: 10.1111/bph.12817.

PMID:
24930520
5.

MALDI-MSI and label-free LC-ESI-MS/MS shotgun proteomics to investigate protein induction in a murine fibrosarcoma model following treatment with a vascular disrupting agent.

Cole LM, Bluff JE, Carolan VA, Paley MN, Tozer GM, Clench MR.

Proteomics. 2014 Apr;14(7-8):890-903. doi: 10.1002/pmic.201300429.

PMID:
24520073
6.

A system for accurate and automated injection of hyperpolarized substrate with minimal dead time and scalable volumes over a large range.

Reynolds S, Bucur A, Port M, Alizadeh T, Kazan SM, Tozer GM, Paley MN.

J Magn Reson. 2014 Feb;239:1-8. doi: 10.1016/j.jmr.2013.10.024. Epub 2013 Nov 22.

7.

Recombinant " IMS TAG" proteins--a new method for validating bottom-up matrix-assisted laser desorption/ionisation ion mobility separation mass spectrometry imaging.

Cole LM, Mahmoud K, Haywood-Small S, Tozer GM, Smith DP, Clench MR.

Rapid Commun Mass Spectrom. 2013 Nov 15;27(21):2355-62. doi: 10.1002/rcm.6693.

PMID:
24097391
8.

Influence of soluble or matrix-bound isoforms of vascular endothelial growth factor-A on tumor response to vascular-targeted strategies.

Akerman S, Fisher M, Daniel RA, Lefley D, Reyes-Aldasoro CC, Lunt SJ, Harris S, Bjorndahl M, Williams LJ, Evans H, Barber PR, Prise VE, Vojnovic B, Kanthou C, Tozer GM.

Int J Cancer. 2013 Dec 1;133(11):2563-76. doi: 10.1002/ijc.28281. Epub 2013 Jul 10.

PMID:
23712501
9.

Kinetic modeling of hyperpolarized (13)C pyruvate metabolism in tumors using a measured arterial input function.

Kazan SM, Reynolds S, Kennerley A, Wholey E, Bluff JE, Berwick J, Cunningham VJ, Paley MN, Tozer GM.

Magn Reson Med. 2013 Oct;70(4):943-53. doi: 10.1002/mrm.24546. Epub 2012 Nov 20.

PMID:
23169010
10.

Online chromatic and scale-space microvessel-tracing analysis for transmitted light optical images.

Reyes-Aldasoro CC, Björndahl MA, Akerman S, Ibrahim J, Griffiths MK, Tozer GM.

Microvasc Res. 2012 Nov;84(3):330-9. doi: 10.1016/j.mvr.2012.09.002. Epub 2012 Sep 14.

PMID:
22982542
11.

Generation of a novel mouse model for the inducible depletion of macrophages in vivo.

Gheryani N, Coffelt SB, Gartland A, Rumney RM, Kiss-Toth E, Lewis CE, Tozer GM, Greaves DR, Dear TN, Miller G.

Genesis. 2013 Jan;51(1):41-9. doi: 10.1002/dvg.22343. Epub 2012 Sep 20.

PMID:
22927121
12.

Do anti-angiogenic VEGF (VEGFxxxb) isoforms exist? A cautionary tale.

Harris S, Craze M, Newton J, Fisher M, Shima DT, Tozer GM, Kanthou C.

PLoS One. 2012;7(5):e35231. doi: 10.1371/journal.pone.0035231. Epub 2012 May 2.

13.

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice.

Welford AF, Biziato D, Coffelt SB, Nucera S, Fisher M, Pucci F, Di Serio C, Naldini L, De Palma M, Tozer GM, Lewis CE.

J Clin Invest. 2011 May;121(5):1969-73. doi: 10.1172/JCI44562. Epub 2011 Apr 1.

14.

Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI.

Cole LM, Djidja MC, Bluff J, Claude E, Carolan VA, Paley M, Tozer GM, Clench MR.

Methods. 2011 Aug;54(4):442-53. doi: 10.1016/j.ymeth.2011.03.007. Epub 2011 Mar 23.

PMID:
21439384
15.

Vascular effects dominate solid tumor response to treatment with combretastatin A-4-phosphate.

Lunt SJ, Akerman S, Hill SA, Fisher M, Wright VJ, Reyes-Aldasoro CC, Tozer GM, Kanthou C.

Int J Cancer. 2011 Oct 15;129(8):1979-89. doi: 10.1002/ijc.25848. Epub 2011 Apr 13.

PMID:
21154772
16.

An automatic algorithm for the segmentation and morphological analysis of microvessels in immunostained histological tumour sections.

Reyes-Aldasoro CC, Williams LJ, Akerman S, Kanthou C, Tozer GM.

J Microsc. 2011 Jun;242(3):262-78. doi: 10.1111/j.1365-2818.2010.03464.x. Epub 2010 Nov 18.

PMID:
21118252
17.

Microflow of fluorescently labelled red blood cells in tumours expressing single isoforms of VEGF and their response to vascular targeting agents.

Akerman S, Reyes-Aldasoro CC, Fisher M, Pettyjohn KL, Björndahl MA, Evans H, Tozer GM.

Med Eng Phys. 2011 Sep;33(7):805-9. doi: 10.1016/j.medengphy.2010.09.006. Epub 2010 Oct 8.

PMID:
20933455
18.

CAIMAN: an online algorithm repository for Cancer Image Analysis.

Reyes-Aldasoro CC, Griffiths MK, Savas D, Tozer GM.

Comput Methods Programs Biomed. 2011 Aug;103(2):97-103. doi: 10.1016/j.cmpb.2010.07.007. Epub 2010 Aug 5.

PMID:
20691494
19.

Guidelines for the welfare and use of animals in cancer research.

Workman P, Aboagye EO, Balkwill F, Balmain A, Bruder G, Chaplin DJ, Double JA, Everitt J, Farningham DA, Glennie MJ, Kelland LR, Robinson V, Stratford IJ, Tozer GM, Watson S, Wedge SR, Eccles SA; Committee of the National Cancer Research Institute.

Br J Cancer. 2010 May 25;102(11):1555-77. doi: 10.1038/sj.bjc.6605642.

20.

Application of intravital microscopy in studies of tumor microcirculation.

Lunt SJ, Gray C, Reyes-Aldasoro CC, Matcher SJ, Tozer GM.

J Biomed Opt. 2010 Jan-Feb;15(1):011113. doi: 10.1117/1.3281674. Review.

PMID:
20210439
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