Toxic ocular effects of ethambutol.
CMAJ. 1988.
PMID: 3345472
Free PMC article.
No abstract available.
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found by citation matching
Toxic ocular effects of ethambutol.
CMAJ. 1987.
PMID: 3607664
Free PMC article.
Search results
Page 1
Ocular toxicity of ethambutol.
Hong Kong Med J. 2006 Feb;12(1):56-60.
Hong Kong Med J. 2006.
PMID: 16495590
Free article.
Review.
OBJECTIVE: To review the literature on ocular toxicity of ethambutol--its background, clinical presentation, toxicity characteristics, management, monitoring, and preventive measures. ...International guidelines on prevention and early detection of …
OBJECTIVE: To review the literature on ocular toxicity of ethambutol--its background, clinical presentation, toxicit …
Ocular Toxicity of Ethambutol During Both Intensive and Continuation Phases of Anti-Tubercular Therapy in Children.
Indian Pediatr. 2022 Nov 15;59(11):863-866.
Indian Pediatr. 2022.
PMID: 36370014
Free article.
OBJECTIVE: The study was conducted to evaluate the ocular toxicity of ethambutol given in both intensive and continuation phases of treatment in children with drug-sensitive tuberculosis. METHODS: A prospective study of 94 eyes from 47 patients receiving an …
OBJECTIVE: The study was conducted to evaluate the ocular toxicity of ethambutol given in both intensive and continuati …
Incidence of toxic optic neuropathy with low-dose ethambutol.
Int J Tuberc Lung Dis. 2016 Feb;20(2):261-4. doi: 10.5588/ijtld.15.0275.
Int J Tuberc Lung Dis. 2016.
PMID: 26792482
OBJECTIVE: To investigate the incidence of ethambutol (EMB) induced optic neuropathy prescribed at a relatively low dose of 15 mg/kg/day for the treatment of tuberculosis (TB) or Mycobacterium avium complex (MAC) lung disease. ...RESULTS: Of the 415 patients included in th …
OBJECTIVE: To investigate the incidence of ethambutol (EMB) induced optic neuropathy prescribed at a relatively low dose of 15 mg/kg/ …
Ocular toxicology.
Curr Opin Ophthalmol. 1994 Dec;5(6):110-4. doi: 10.1097/00055735-199412000-00018.
Curr Opin Ophthalmol. 1994.
PMID: 10172409
Review.
This review of recent articles on ocular toxicology concentrates on undesirable effects on the eye induced by systemically used xenobiotics. ...Also reviewed are the role of hormone levels in diabetic retinopathy, the therapeutic use of clonidine for perioperative i …
This review of recent articles on ocular toxicology concentrates on undesirable effects on the eye induced by systemically use …
[Exogenously induced retinopathies].
Klin Monbl Augenheilkd. 2022 Dec;239(12):1493-1511. doi: 10.1055/a-1961-8166. Epub 2022 Nov 17.
Klin Monbl Augenheilkd. 2022.
PMID: 36395811
German.
Exogenously induced retinopathies can be caused by consumation of stimulating substances, systemic or ocular medications, vaccinations, light or irradiation. Some of the effects are transient, whereas other effects induce irreversible toxic reactions. …
Exogenously induced retinopathies can be caused by consumation of stimulating substances, systemic or ocular medications, vaccination …
Ocular side effects of selected systemic drugs.
Optom Clin. 1992;2(4):73-96.
Optom Clin. 1992.
PMID: 1363080
Review.
The antituberculosis agents ethambutol and isoniazid have been implicated as causes of reduced acuity, visual field defects, and disturbances of color vision. Optic neuritis and retrobulbar neuritis may result from the use of chloramphenicol. This paper describes these and …
The antituberculosis agents ethambutol and isoniazid have been implicated as causes of reduced acuity, visual field defects, and dist …
The effect of thiamine pyrophosphate on ethambutol-induced ocular toxicity.
Cutan Ocul Toxicol. 2016 Sep;35(3):222-7. doi: 10.3109/15569527.2015.1077857. Epub 2015 Aug 24.
Cutan Ocul Toxicol. 2016.
PMID: 26339826
The protective effect of thiamine pyrophosphate against oxidative damage in some tissues has been reported, but no information on the protective effects of thiamine pyrophosphate against ethambutol-induced oxidative retinal damage has been found in the medica …
The protective effect of thiamine pyrophosphate against oxidative damage in some tissues has been reported, but no information on the …
Exploration of the Plausible Mechanism of Ethambutol Induced Ocular Toxicity by Using Proteomics Informed Physiologically Based Pharmacokinetic (PBPK) Modeling.
Pharm Res. 2022 Apr;39(4):677-689. doi: 10.1007/s11095-022-03227-9. Epub 2022 Mar 17.
Pharm Res. 2022.
PMID: 35301670
The exact mechanism of its eye toxicity is unknown; however, proposition is metal chelating effect of both EMB and its metabolite 2,2'-(ethylenediamino)-dibutyric acid (EDBA). ...These observations meant that once EDBA was formed in the eye, it was not permeated out …
The exact mechanism of its eye toxicity is unknown; however, proposition is metal chelating effect of both EMB and its metabol …
The use of optical coherence tomography for the detection of ocular toxicity by ethambutol.
PLoS One. 2018 Nov 8;13(11):e0204655. doi: 10.1371/journal.pone.0204655. eCollection 2018.
PLoS One. 2018.
PMID: 30408036
Free PMC article.
Clinical Trial.
METHODS: Thirty patients with ethambutol were recruited from the reference service of tuberculosis treatment at the Federal University of Espirito Santo from May 2015 to July 2016. After clinical history, the following parameters were analyzed; best corrected visual acuity …
METHODS: Thirty patients with ethambutol were recruited from the reference service of tuberculosis treatment at the Federal Universit …
Lower dose of ethambutol may reduce ocular toxicity without radiological deterioration for Mycobacterium avium complex pulmonary disease.
Respir Investig. 2021 Nov;59(6):777-782. doi: 10.1016/j.resinv.2021.06.010. Epub 2021 Aug 10.
Respir Investig. 2021.
PMID: 34389250
Clinical Trial.
BACKGROUND: Ethambutol ocular toxicity is a major problem during combination chemotherapy for Mycobacterium avium complex (MAC) pulmonary disease (MAC-PD) due to years-long therapy for MAC. ...Macrolide resistance developed in one patient per group during fol …
BACKGROUND: Ethambutol ocular toxicity is a major problem during combination chemotherapy for Mycobacterium avium compl …
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