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Results: 1 to 20 of 56

1.

hSSB1 (NABP2/ OBFC2B) is required for the repair of 8-oxo-guanine by the hOGG1-mediated base excision repair pathway.

Paquet N, Adams MN, Leong V, Ashton NW, Touma C, Gamsjaeger R, Cubeddu L, Beard S, Burgess JT, Bolderson E, O'Byrne KJ, Richard DJ.

Nucleic Acids Res. 2015 Aug 10. pii: gkv790. [Epub ahead of print]

2.

RNA expression profiling in depressed patients suggests retinoid-related orphan receptor alpha as a biomarker for antidepressant response.

Hennings JM, Uhr M, Klengel T, Weber P, Pütz B, Touma C, Czamara D, Ising M, Holsboer F, Lucae S.

Transl Psychiatry. 2015 Mar 31;5:e538. doi: 10.1038/tp.2015.9.

3.

A role for synapsin in FKBP51 modulation of stress responsiveness: Convergent evidence from animal and human studies.

Schmidt U, Buell DR, Ionescu IA, Gassen NC, Holsboer F, Cox MB, Novak B, Huber C, Hartmann J, Schmidt MV, Touma C, Rein T, Herrmann L.

Psychoneuroendocrinology. 2015 Feb;52:43-58. doi: 10.1016/j.psyneuen.2014.11.005. Epub 2014 Nov 11.

PMID:
25459892
4.

Selective inhibitors of the FK506-binding protein 51 by induced fit.

Gaali S, Kirschner A, Cuboni S, Hartmann J, Kozany C, Balsevich G, Namendorf C, Fernandez-Vizarra P, Sippel C, Zannas AS, Draenert R, Binder EB, Almeida OF, Rühter G, Uhr M, Schmidt MV, Touma C, Bracher A, Hausch F.

Nat Chem Biol. 2015 Jan;11(1):33-7. doi: 10.1038/nchembio.1699. Epub 2014 Dec 1.

PMID:
25436518
5.

The structural basis of DNA binding by the single-stranded DNA-binding protein from Sulfolobus solfataricus.

Gamsjaeger R, Kariawasam R, Gimenez AX, Touma C, McIlwain E, Bernardo RE, Shepherd NE, Ataide SF, Dong Q, Richard DJ, White MF, Cubeddu L.

Biochem J. 2015 Jan 15;465(2):337-46. doi: 10.1042/BJ20141140.

PMID:
25367669
6.

Mice selected for extremes in stress reactivity reveal key endophenotypes of major depression: a translational approach.

Heinzmann JM, Kloiber S, Ebling-Mattos G, Bielohuby M, Schmidt MV, Palme R, Holsboer F, Uhr M, Ising M, Touma C.

Psychoneuroendocrinology. 2014 Nov;49:229-43. doi: 10.1016/j.psyneuen.2014.07.008. Epub 2014 Jul 23.

PMID:
25123105
7.

Blunted HPA axis reactivity reveals glucocorticoid system dysbalance in a mouse model of high anxiety-related behavior.

Sotnikov S, Wittmann A, Bunck M, Bauer S, Deussing J, Schmidt M, Touma C, Landgraf R, Czibere L.

Psychoneuroendocrinology. 2014 Oct;48:41-51. doi: 10.1016/j.psyneuen.2014.06.006. Epub 2014 Jun 17.

PMID:
24995583
8.

Genetic interactions with sex make a relatively small contribution to the heritability of complex traits in mice.

Krohn J, Speed D, Palme R, Touma C, Mott R, Flint J.

PLoS One. 2014 May 8;9(5):e96450. doi: 10.1371/journal.pone.0096450. eCollection 2014.

9.

Environmental enrichment alters splenic immune cell composition and enhances secondary influenza vaccine responses in mice.

Gurfein BT, Davidenko O, Premenko-Lanier M, Milush JM, Acree M, Dallman MF, Touma C, Palme R, York VA, Fromentin G, Darcel N, Nixon DF, Hecht FM.

Mol Med. 2014 Apr 22;20:179-90. doi: 10.2119/molmed.2013.00158.

10.

Association of obstructive sleep apnea in rapid eye movement sleep with reduced glycemic control in type 2 diabetes: therapeutic implications.

Grimaldi D, Beccuti G, Touma C, Van Cauter E, Mokhlesi B.

Diabetes Care. 2014 Feb;37(2):355-63. doi: 10.2337/dc13-0933. Epub 2013 Oct 7.

11.

Corticosteroid-binding globulin contributes to the neuroendocrine phenotype of mice selected for extremes in stress reactivity.

Mattos GE, Heinzmann JM, Norkowski S, Helbling JC, Minni AM, Moisan MP, Touma C.

J Endocrinol. 2013 Oct 28;219(3):217-29. doi: 10.1530/JOE-13-0255. Print 2013 Dec.

12.

S100B overexpression increases behavioral and neural plasticity in response to the social environment during adolescence.

Buschert J, Hohoff C, Touma C, Palme R, Rothermundt M, Arolt V, Zhang W, Ambrée O.

J Psychiatr Res. 2013 Nov;47(11):1791-9. doi: 10.1016/j.jpsychires.2013.08.001. Epub 2013 Aug 22.

PMID:
23972702
13.

Backbone and side-chain ¹H, ¹³C and ¹⁵N resonance assignments of the OB domain of the single stranded DNA binding protein from Sulfolobus solfataricus and chemical shift mapping of the DNA-binding interface.

Gamsjaeger R, Kariawasam R, Touma C, Kwan AH, White MF, Cubeddu L.

Biomol NMR Assign. 2014 Oct;8(2):243-6. doi: 10.1007/s12104-013-9492-4. Epub 2013 Jun 8.

PMID:
23749431
14.

Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments.

Gamsjaeger R, Kariawasam R, Bang LH, Touma C, Nguyen CD, Matthews JM, Cubeddu L, Mackay JP.

Anal Biochem. 2013 Sep 15;440(2):178-85. doi: 10.1016/j.ab.2013.04.030. Epub 2013 May 31.

PMID:
23727560
15.

The endocrine stress response is linked to one specific locus on chromosome 3 in a mouse model based on extremes in trait anxiety.

Gonik M, Frank E, Keßler MS, Czamara D, Bunck M, Yen YC, Pütz B, Holsboer F, Bettecken T, Landgraf R, Müller-Myhsok B, Touma C, Czibere L.

BMC Genomics. 2012 Oct 31;13:579. doi: 10.1186/1471-2164-13-579.

16.

Do social statuses affect the startle reflex in male mice?

Coudereau JP, Sreng L, Palme R, Touma C, Pratte M.

Behav Brain Res. 2012 Sep 1;234(1):117-20. doi: 10.1016/j.bbr.2012.06.009. Epub 2012 Jun 20.

PMID:
22728306
17.

Dendritic morphology of hippocampal and amygdalar neurons in adolescent mice is resilient to genetic differences in stress reactivity.

Pillai AG, de Jong D, Kanatsou S, Krugers H, Knapman A, Heinzmann JM, Holsboer F, Landgraf R, Joëls M, Touma C.

PLoS One. 2012;7(6):e38971. doi: 10.1371/journal.pone.0038971. Epub 2012 Jun 12.

18.

Urocortin 2 modulates aspects of social behaviour in mice.

Breu J, Touma C, Hölter SM, Knapman A, Wurst W, Deussing JM.

Behav Brain Res. 2012 Aug 1;233(2):331-6. doi: 10.1016/j.bbr.2012.05.031. Epub 2012 May 26.

PMID:
22640813
19.

The calm mouse: an animal model of stress reduction.

Gurfein BT, Stamm AW, Bacchetti P, Dallman MF, Nadkarni NA, Milush JM, Touma C, Palme R, Di Borgo CP, Fromentin G, Lown-Hecht R, Konsman JP, Acree M, Premenko-Lanier M, Darcel N, Hecht FM, Nixon DF.

Mol Med. 2012 May 9;18:606-17. doi: 10.2119/molmed.2012.00053.

20.

Increased stress reactivity is associated with reduced hippocampal activity and neuronal integrity along with changes in energy metabolism.

Knapman A, Kaltwasser SF, Martins-de-Souza D, Holsboer F, Landgraf R, Turck CW, Czisch M, Touma C.

Eur J Neurosci. 2012 Feb;35(3):412-22. doi: 10.1111/j.1460-9568.2011.07968.x.

PMID:
22288479
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