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Results: 9

1.

Olanzapine-induced changes in glucose metabolism are independent of the melanin-concentrating hormone system.

Girault EM, Toonen PW, Eggels L, Foppen E, Ackermans MT, la Fleur SE, Fliers E, Kalsbeek A.

Psychoneuroendocrinology. 2013 Nov;38(11):2640-6. doi: 10.1016/j.psyneuen.2013.06.021. Epub 2013 Jul 13.

PMID:
23856185
[PubMed - indexed for MEDLINE]
2.

Pmch-deficiency in rats is associated with normal adipocyte differentiation and lower sympathetic adipose drive.

Mul JD, O'Duibhir E, Shrestha YB, Koppen A, Vargoviç P, Toonen PW, Zarebidaki E, Kvetnansky R, Kalkhoven E, Cuppen E, Bartness TJ.

PLoS One. 2013;8(3):e60214. doi: 10.1371/journal.pone.0060214. Epub 2013 Mar 26.

PMID:
23555928
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Homozygous and heterozygous p53 knockout rats develop metastasizing sarcomas with high frequency.

van Boxtel R, Kuiper RV, Toonen PW, van Heesch S, Hermsen R, de Bruin A, Cuppen E.

Am J Pathol. 2011 Oct;179(4):1616-22. doi: 10.1016/j.ajpath.2011.06.036. Epub 2011 Aug 18.

PMID:
21854749
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A hypomorphic mutation in Lpin1 induces progressively improving neuropathy and lipodystrophy in the rat.

Mul JD, Nadra K, Jagalur NB, Nijman IJ, Toonen PW, Médard JJ, Grès S, de Bruin A, Han GS, Brouwers JF, Carman GM, Saulnier-Blache JS, Meijer D, Chrast R, Cuppen E.

J Biol Chem. 2011 Jul 29;286(30):26781-93. doi: 10.1074/jbc.M110.197947. Epub 2011 Jun 1.

PMID:
21715287
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Chronic loss of melanin-concentrating hormone affects motivational aspects of feeding in the rat.

Mul JD, la Fleur SE, Toonen PW, Afrasiab-Middelman A, Binnekade R, Schetters D, Verheij MM, Sears RM, Homberg JR, Schoffelmeer AN, Adan RA, DiLeone RJ, De Vries TJ, Cuppen E.

PLoS One. 2011 May 5;6(5):e19600. doi: 10.1371/journal.pone.0019600.

PMID:
21573180
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Melanocortin receptor 4 deficiency affects body weight regulation, grooming behavior, and substrate preference in the rat.

Mul JD, van Boxtel R, Bergen DJ, Brans MA, Brakkee JH, Toonen PW, Garner KM, Adan RA, Cuppen E.

Obesity (Silver Spring). 2012 Mar;20(3):612-21. doi: 10.1038/oby.2011.81. Epub 2011 Apr 28. Erratum in: Obesity (Silver Spring). 2012 Jul;20(7):1545. Dosage error in article text.

PMID:
21527895
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Pmch expression during early development is critical for normal energy homeostasis.

Mul JD, Yi CX, van den Berg SA, Ruiter M, Toonen PW, van der Elst MC, Voshol PJ, Ellenbroek BA, Kalsbeek A, la Fleur SE, Cuppen E.

Am J Physiol Endocrinol Metab. 2010 Mar;298(3):E477-88. doi: 10.1152/ajpendo.00154.2009. Epub 2009 Nov 24.

PMID:
19934402
[PubMed - indexed for MEDLINE]
Free Article
8.

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E.

BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460.

PMID:
18840264
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

van Boxtel R, Toonen PW, van Roekel HS, Verheul M, Smits BM, Korving J, de Bruin A, Cuppen E.

Carcinogenesis. 2008 Jun;29(6):1290-7. doi: 10.1093/carcin/bgn094. Epub 2008 Apr 15.

PMID:
18417481
[PubMed - indexed for MEDLINE]
Free Article

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