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Items: 1 to 20 of 401

1.

CHiCP: a web-based tool for the integrative and interactive visualization of promoter capture Hi-C datasets.

Schofield EC, Carver T, Achuthan P, Freire-Pritchett P, Spivakov M, Todd JA, Burren OS.

Bioinformatics. 2016 Apr 8. pii: btw173. [Epub ahead of print]

2.

β-cell specific T-lymphocyte response has a distinct inflammatory phenotype in children with Type 1 diabetes compared with adults.

Arif S, Gibson VB, Nguyen V, Bingley PJ, Todd JA, Guy C, Dunger DB, Dayan CM, Powrie J, Lorenc A, Peakman M.

Diabet Med. 2016 May 6. doi: 10.1111/dme.13153. [Epub ahead of print]

PMID:
27151105
3.

Intolerable secretion and diabetes in tolerant transgenic mice, revisited.

Todd JA.

Nat Genet. 2016 Apr 27;48(5):476-7. doi: 10.1038/ng.3560.

PMID:
27120442
4.

Primary prevention of beta-cell autoimmunity and type 1 diabetes - The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives.

Ziegler AG, Danne T, Dunger DB, Berner R, Puff R, Kiess W, Agiostratidou G, Todd JA, Bonifacio E.

Mol Metab. 2016 Feb 22;5(4):255-62. doi: 10.1016/j.molmet.2016.02.003. eCollection 2016 Apr. Review.

5.

Evaluation of near-surface stress distributions in dissimilar welded joint by scanning acoustic microscopy.

Kwak DR, Yoshida S, Sasaki T, Todd JA, Park IK.

Ultrasonics. 2016 Apr;67:9-17. doi: 10.1016/j.ultras.2015.12.006. Epub 2015 Dec 19.

PMID:
26773788
6.

Protocol of the adaptive study of IL-2 dose frequency on regulatory T cells in type 1 diabetes (DILfrequency): a mechanistic, non-randomised, repeat dose, open-label, response-adaptive study.

Truman LA, Pekalski ML, Kareclas P, Evangelou M, Walker NM, Howlett J, Mander AP, Kennet J, Wicker LS, Bond S, Todd JA, Waldron-Lynch F.

BMJ Open. 2015 Dec 8;5(12):e009799. doi: 10.1136/bmjopen-2015-009799.

7.

Ptpn22 and Cd2 Variations Are Associated with Altered Protein Expression and Susceptibility to Type 1 Diabetes in Nonobese Diabetic Mice.

Fraser HI, Howlett S, Clark J, Rainbow DB, Stanford SM, Wu DJ, Hsieh YW, Maine CJ, Christensen M, Kuchroo V, Sherman LA, Podolin PL, Todd JA, Steward CA, Peterson LB, Bottini N, Wicker LS.

J Immunol. 2015 Nov 15;195(10):4841-52. doi: 10.4049/jimmunol.1402654. Epub 2015 Oct 5.

8.

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Rainbow DB, Yang X, Burren O, Pekalski ML, Smyth DJ, Klarqvist MD, Penkett CJ, Brugger K, Martin H, Todd JA, Wallace C, Wicker LS.

Eur J Immunol. 2015 Nov;45(11):3200-3. doi: 10.1002/eji.201545646. Epub 2015 Oct 1. No abstract available.

9.

Erratum. Blood and Islet Phenotypes Indicate Immunological Heterogeneity in Type 1 Diabetes. Diabetes 2014;63:3835-3845.

Arif S, Leete P, Nguyen V, Marks K, Nor NM, Estorninho M, Kronenberg-Versteeg D, Bingley PJ, Todd JA, Guy C, Dunger DB, Powrie J, Willcox A, Foulis AK, Richardson SJ, de Rinaldis E, Morgan NG, Lorenc A, Peakman M.

Diabetes. 2015 Sep;64(9):3334. doi: 10.2337/db15-er09a. No abstract available.

10.

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Yang JH, Cutler AJ, Ferreira RC, Reading JL, Cooper NJ, Wallace C, Clarke P, Smyth DJ, Boyce CS, Gao GJ, Todd JA, Wicker LS, Tree TI.

Diabetes. 2015 Nov;64(11):3891-902. doi: 10.2337/db15-0516. Epub 2015 Jul 29.

11.

Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Fortune MD, Guo H, Burren O, Schofield E, Walker NM, Ban M, Sawcer SJ, Bowes J, Worthington J, Barton A, Eyre S, Todd JA, Wallace C.

Nat Genet. 2015 Aug;47(8):962. doi: 10.1038/ng0815-962c. No abstract available.

PMID:
26220137
12.

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk.

Hu X, Deutsch AJ, Lenz TL, Onengut-Gumuscu S, Han B, Chen WM, Howson JM, Todd JA, de Bakker PI, Rich SS, Raychaudhuri S.

Nat Genet. 2015 Aug;47(8):898-905. doi: 10.1038/ng.3353. Epub 2015 Jul 13.

PMID:
26168013
13.

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

Wallace C, Cutler AJ, Pontikos N, Pekalski ML, Burren OS, Cooper JD, García AR, Ferreira RC, Guo H, Walker NM, Smyth DJ, Rich SS, Onengut-Gumuscu S, Sawcer SJ, Ban M, Richardson S, Todd JA, Wicker LS.

PLoS Genet. 2015 Jun 24;11(6):e1005272. doi: 10.1371/journal.pgen.1005272. eCollection 2015 Jun.

14.

Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls.

Fortune MD, Guo H, Burren O, Schofield E, Walker NM, Ban M, Sawcer SJ, Bowes J, Worthington J, Barton A, Eyre S, Todd JA, Wallace C.

Nat Genet. 2015 Jul;47(7):839-46. doi: 10.1038/ng.3330. Epub 2015 Jun 8. Erratum in: Nat Genet. 2015 Aug;47(8):962.

15.

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Dopico XC, Evangelou M, Ferreira RC, Guo H, Pekalski ML, Smyth DJ, Cooper N, Burren OS, Fulford AJ, Hennig BJ, Prentice AM, Ziegler AG, Bonifacio E, Wallace C, Todd JA.

Nat Commun. 2015 May 12;6:7000. doi: 10.1038/ncomms8000.

16.

Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D).

Heywood J, Evangelou M, Goymer D, Kennet J, Anselmiova K, Guy C, O'Brien C, Nutland S, Brown J, Walker NM, Todd JA, Waldron-Lynch F.

Trials. 2015 Mar 11;16:86. doi: 10.1186/s13063-015-0583-7.

17.

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium, Todd JA, Wallace C, Concannon P, Rich SS.

Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9.

18.

Integration of disease association and eQTL data using a Bayesian colocalisation approach highlights six candidate causal genes in immune-mediated diseases.

Guo H, Fortune MD, Burren OS, Schofield E, Todd JA, Wallace C.

Hum Mol Genet. 2015 Jun 15;24(12):3305-13. doi: 10.1093/hmg/ddv077. Epub 2015 Mar 5.

19.

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Ferreira RC, Simons HZ, Thompson WS, Cutler AJ, Dopico XC, Smyth DJ, Mashar M, Schuilenburg H, Walker NM, Dunger DB, Wallace C, Todd JA, Wicker LS, Pekalski ML.

Diabetologia. 2015 Apr;58(4):781-90. doi: 10.1007/s00125-015-3509-8. Epub 2015 Feb 6.

20.

A review of the Polystira clade--the Neotropic's largest marine gastropod radiation (Neogastropoda: Conoidea: Turridae sensu stricto).

Todd JA, Rawlings TA.

Zootaxa. 2014 Nov 18;3884(5):445-91. doi: 10.11646/zootaxa.3884.5.5.

PMID:
25543802
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