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Results: 1 to 20 of 221

1.

Novel oxazolinyl derivatives of pregna-5,17(20)-diene as 17α-hydroxylase/17,20-lyase (CYP17A1) inhibitors.

Kuzikov AV, Dugin NO, Stulov SV, Shcherbinin DS, Zharkova MS, Tkachev YV, Timofeev VP, Veselovsky AV, Shumyantseva VV, Misharin AY.

Steroids. 2014 Oct;88:66-71. doi: 10.1016/j.steroids.2014.06.014. Epub 2014 Jun 24.

PMID:
24971814
[PubMed - in process]
2.

3'-Azidothymidine in the active site of Escherichia coli thymidine phosphorylase: the peculiarity of the binding on the basis of X-ray study.

Timofeev V, Abramchik Y, Zhukhlistova N, Muravieva T, Fateev I, Esipov R, Kuranova I.

Acta Crystallogr D Biol Crystallogr. 2014 Apr;70(Pt 4):1155-65. doi: 10.1107/S1399004714001904. Epub 2014 Mar 21.

PMID:
24699659
[PubMed - in process]
3.

A new type of donor-acceptor cyclopropane reactivity: the generation of formal 1,2- and 1,4-dipoles.

Novikov RA, Tarasova AV, Korolev VA, Timofeev VP, Tomilov YV.

Angew Chem Int Ed Engl. 2014 Mar 17;53(12):3187-91. doi: 10.1002/anie.201306186. Epub 2014 Feb 19.

PMID:
24554497
[PubMed - in process]
4.

Lipophilic derivatives of natural chlorins: synthesis, mixed micelles with phospholipids, and uptake by cultured cells.

Ponomarev GV, Solovieva MN, Dugin NO, Zavialova MG, Mehtiev AR, Misharin AY, Novikov RA, Tkachev YV, Popenko VI, Timofeev VP.

Bioorg Med Chem. 2013 Sep 1;21(17):5420-7. doi: 10.1016/j.bmc.2013.06.016. Epub 2013 Jun 14.

PMID:
23820573
[PubMed - indexed for MEDLINE]
5.

Three-dimensional structure of carboxypeptidase T from Thermoactinomyces vulgaris in complex with N-BOC-L-leucine.

Timofeev VI, Kuznetsov SA, Akparov VKh, Chestukhina GG, Kuranova IP.

Biochemistry (Mosc). 2013 Mar;78(3):252-9. doi: 10.1134/S0006297913030061.

PMID:
23586718
[PubMed - indexed for MEDLINE]
Free Article
6.

Synthesis and molecular modeling of (4'R)- and (4'S)- 4'-substituted 2'-{[(E)-androst-5-en-17-ylidene]-methyl}oxazolines.

Stulov SV, Mankevich OV, Novikov RA, Tkachev YV, Timofeev VP, Dugin NO, Pozdnev VF, Fedyushkina IV, Scherbinin DS, Veselovsky AV, Misharin AY.

Steroids. 2013 May;78(5):521-7. doi: 10.1016/j.steroids.2013.02.014. Epub 2013 Mar 13.

PMID:
23499823
[PubMed - indexed for MEDLINE]
7.

Pregna-5,17(20)-dien-21-oyl amides affecting sterol and triglyceride biosynthesis in Hep G2 cells.

Stulov SV, Mankevich OV, Dugin NO, Novikov RA, Timofeev VP, Misharin AY.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):2014-8. doi: 10.1016/j.bmcl.2013.02.026. Epub 2013 Feb 13.

PMID:
23466231
[PubMed - indexed for MEDLINE]
8.

X-ray study of the conformational changes in the molecule of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis during the catalyzed reaction.

Timofeev V, Smirnova E, Chupova L, Esipov R, Kuranova I.

Acta Crystallogr D Biol Crystallogr. 2012 Dec;68(Pt 12):1660-70. doi: 10.1107/S0907444912040206. Epub 2012 Nov 9.

PMID:
23151631
[PubMed - indexed for MEDLINE]
9.

Initial stage growth of GexSi1-x layers and Ge quantum dot formation on GexSi1-x surface by MBE.

Nikiforov AI, Timofeev VA, Teys SA, Gutakovsky AK, Pchelyakov OP.

Nanoscale Res Lett. 2012 Oct 9;7(1):561. doi: 10.1186/1556-276X-7-561.

PMID:
23043796
[PubMed]
Free PMC Article
10.

Photovoltaic Ge/Si quantum dot detectors operating in the mid-wave atmospheric window (3 to 5 μm).

Yakimov A, Timofeev V, Bloshkin A, Nikiforov A, Dvurechenskii A.

Nanoscale Res Lett. 2012 Aug 31;7(1):494. doi: 10.1186/1556-276X-7-494.

PMID:
22938028
[PubMed]
Free PMC Article
11.

Stereoselective double lewis acid/organo-catalyzed dimerization of donor-acceptor cyclopropanes into substituted 2-oxabicyclo[3.3.0]octanes.

Novikov RA, Timofeev VP, Tomilov YV.

J Org Chem. 2012 Jul 20;77(14):5993-6006. doi: 10.1021/jo300720d. Epub 2012 Jul 5.

PMID:
22724635
[PubMed - indexed for MEDLINE]
12.

Synthesis of 21-nitrogen substituted pregna-5,17(20)-dienes from pregnenolone.

Stulov SV, Tkachev YV, Novikov RA, Zavialova MG, Timofeev VP, Misharin AY.

Steroids. 2012 Jan;77(1-2):77-84. doi: 10.1016/j.steroids.2011.10.007. Epub 2011 Oct 26.

PMID:
22064217
[PubMed - indexed for MEDLINE]
13.

Formation of Ge-Sn nanodots on Si(100) surfaces by molecular beam epitaxy.

Mashanov V, Ulyanov V, Timofeev V, Nikiforov A, Pchelyakov O, Yu IS, Cheng H.

Nanoscale Res Lett. 2011 Jan 12;6(1):85. doi: 10.1186/1556-276X-6-85.

PMID:
21711584
[PubMed]
Free PMC Article
14.

[Synthesis of secasterol and 24-episecasterol and their toxicity in MCF-7 cells].

Khripach VA, Zhabinskiĭ VN, Gyliakevich OV, Konstantinova OV, Misharin AIu, Mekhtiev AR, Timofeev VP, Tkachev IaV.

Bioorg Khim. 2010 Nov-Dec;36(6):815-24. Russian.

PMID:
21317948
[PubMed - indexed for MEDLINE]
15.

[Regulation of cholesterol biosynthesis and metabolism in Hep G2 cells by delta8(14)-15-ketoergostane derivatives].

Mekhtiev AR, Fedchenko VI, Tkachev IaV, Timofeev VP, Misharin AIu.

Biomed Khim. 2010 Sep-Oct;56(5):576-86. Russian.

PMID:
21254628
[PubMed - indexed for MEDLINE]
16.

Kinetic and spectral parameters of interaction of Citrobacter freundii methionine γ-lyase with amino acids.

Morozova EA, Bazhulina NP, Anufrieva NV, Mamaeva DV, Tkachev YV, Streltsov SA, Timofeev VP, Faleev NG, Demidkina TV.

Biochemistry (Mosc). 2010 Oct;75(10):1272-80.

PMID:
21166645
[PubMed - indexed for MEDLINE]
17.

Stereospecificity of isotopic exchange of C-α-protons of glycine catalyzed by three PLP-dependent lyases: the unusual case of tyrosine phenol-lyase.

Koulikova VV, Zakomirdina LN, Gogoleva OI, Tsvetikova MA, Morozova EA, Komissarov VV, Tkachev YV, Timofeev VP, Demidkina TV, Faleev NG.

Amino Acids. 2011 Nov;41(5):1247-56. doi: 10.1007/s00726-010-0802-1. Epub 2010 Nov 23.

PMID:
21104284
[PubMed - indexed for MEDLINE]
18.

[17(20)E]- and [17(20)Z]-pregna-5,17(20)-dien-21-oylamides. Facile synthesis and primary evaluation for cancer cells proliferation.

Stulov SV, Zavialova MG, Mehtiev AR, Novikov RA, Tkachev YV, Timofeev VP, Misharin AY.

Bioorg Med Chem Lett. 2010 Sep 15;20(18):5495-8. doi: 10.1016/j.bmcl.2010.07.075. Epub 2010 Jul 21.

PMID:
20702093
[PubMed - indexed for MEDLINE]
19.

Chlorin e6-cholesterol conjugate and its copper complex. Simple synthesis and entrapping in phospholipid vesicles.

Nikolaeva IA, Misharin AY, Ponomarev GV, Timofeev VP, Tkachev YV.

Bioorg Med Chem Lett. 2010 May 1;20(9):2872-5. doi: 10.1016/j.bmcl.2010.03.041. Epub 2010 Mar 11.

PMID:
20356740
[PubMed - indexed for MEDLINE]
20.

X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid.

Timofeev VI, Chuprov-Netochin RN, Samigina VR, Bezuglov VV, Miroshnikov KA, Kuranova IP.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Mar 1;66(Pt 3):259-63. doi: 10.1107/S1744309110000461. Epub 2010 Feb 23.

PMID:
20208155
[PubMed - indexed for MEDLINE]
Free PMC Article

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