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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1987 1
1988 1
1989 2
1990 2
1991 4
1992 1
1993 9
1994 8
1995 12
1996 13
1997 8
1998 12
1999 17
2000 21
2001 19
2002 17
2003 7
2004 23
2005 20
2006 17
2007 15
2008 22
2009 17
2010 15
2011 27
2012 29
2013 15
2014 19
2015 20
2016 27
2017 25
2018 22
2019 41
2020 36
2021 32
2022 32
2023 42
2024 18

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611 results

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Page 1
Tilmicosin/gamma-Cyclodextrin complexation through supercritical carbon dioxide assistance and its pharmacokinetic and antibacterial study.
Ding Y, Yu B, Zhang J, Ding C, Zhang Z, Xu S, Li L, Yu H. Ding Y, et al. Eur J Pharm Biopharm. 2022 Dec;181:104-112. doi: 10.1016/j.ejpb.2022.10.024. Epub 2022 Nov 11. Eur J Pharm Biopharm. 2022. PMID: 36375723
The water solubility of tilmicosin was increased 57-fold through complexation with gamma-cyclodextrin, and the release and bioavailability of tilmicosin in the complex were significantly improved. The tilmicosin in complex showed better anti-Streptococcus aga …
The water solubility of tilmicosin was increased 57-fold through complexation with gamma-cyclodextrin, and the release and bioavailab …
The dose regimen formulation of tilmicosin against Lawsonia intracellularis in pigs by pharmacokinetic-pharmacodynamic (PK-PD) model.
Luo W, Qin H, Chen D, Wu M, Meng K, Zhang A, Pan Y, Qu W, Xie S. Luo W, et al. Microb Pathog. 2020 Oct;147:104389. doi: 10.1016/j.micpath.2020.104389. Epub 2020 Jul 21. Microb Pathog. 2020. PMID: 32707311 Review.
In this study, the rational dose regimens of tilmicosin against Lawsonia intracellularis (L. intracellularis) were studied using pharmacokinetic-pharmacodynamic (PK-PD) model approach to provide a maximal efficacy. The healthy and infected pigs were orally administrated th …
In this study, the rational dose regimens of tilmicosin against Lawsonia intracellularis (L. intracellularis) were studied using phar …
Tilmicosin enteric granules and premix to pigs: Antimicrobial susceptibility testing and comparative pharmacokinetics.
Xiong J, Zhu Q, Zhao Y, Yang S, Cao J, Qiu Y. Xiong J, et al. J Vet Pharmacol Ther. 2019 May;42(3):336-345. doi: 10.1111/jvp.12753. Epub 2019 Feb 22. J Vet Pharmacol Ther. 2019. PMID: 30801755
The relative bioavailability of tilmicosin enteric granules to premix was 114.97 7.19%, according to the AUC(0-t) values. These results demonstrated that tilmicosin enteric granules produced faster tilmicosin absorption, slower elimination, larger tissue dist …
The relative bioavailability of tilmicosin enteric granules to premix was 114.97 7.19%, according to the AUC(0-t) values. These resul …
Enhanced antibacterial activity of tilmicosin against Staphylococcus aureus small colony variants by chitosan oligosaccharide-sodium carboxymethyl cellulose composite nanogels.
Luo W, Liu J, Zhang S, Song W, Algharib SA, Chen W. Luo W, et al. J Vet Sci. 2022 Jan;23(1):e1. doi: 10.4142/jvs.21208. Epub 2021 Nov 5. J Vet Sci. 2022. PMID: 34931502 Free PMC article.
The inhibition zone of native tilmicosin, tilmicosin standard, and tilmicosin composite nanogels were 2.13 0.07, 3.35 0.11, and 1.46 0.04 cm, respectively. The minimum inhibitory concentration of native tilmicosin, tilmicosin standard, and ti …
The inhibition zone of native tilmicosin, tilmicosin standard, and tilmicosin composite nanogels were 2.13 0.07, 3.35 0 …
Pharmacokinetics of tilmicosin in chicken joints based on a novel microdialysis sampling method.
Zhang N, Yan X, Liu J, Zhou S, Zhou M, Song S, Yao Z, Jia Y, Yuan S. Zhang N, et al. J Vet Pharmacol Ther. 2023 Jul;46(4):257-263. doi: 10.1111/jvp.13118. Epub 2023 Mar 21. J Vet Pharmacol Ther. 2023. PMID: 36945149
However, the PK study of tilmicosin in chicken joint has not been reported. The aim of this study was to explore the PK characteristics and penetration of tilmicosin by microdialysis incorporated with High-Performance Liquid Chromatography Mass Spectrometry (HPLC-MS …
However, the PK study of tilmicosin in chicken joint has not been reported. The aim of this study was to explore the PK characteristi …
The effect of tilmicosin and diclofenac sodium combination on cardiac biomarkers in sheep.
Yildiz R, Durna Corum D, Corum O, Ider M, Atik O, Ok M, Uney K. Yildiz R, et al. Pol J Vet Sci. 2023 Mar;26(1):5-12. doi: 10.24425/pjvs.2023.145001. Pol J Vet Sci. 2023. PMID: 36961261
The aim of this study was to investigate the cardiotoxic effect of the combination of tilmicosin and diclofenac sodium in sheep. Thirty-two sheep were used and were randomly divided into four equal groups as tilmicosin (T), diclofenac sodium (D), tilmicosin+d …
The aim of this study was to investigate the cardiotoxic effect of the combination of tilmicosin and diclofenac sodium in sheep. Thir …
Preparation of tilmicosin-resin complex microsphere and its Pharmacokinetics study in rat.
Li D, Zou K, Wang X, Huang Q, Li S, Zuo H, Hu C, Li Z. Li D, et al. Pak J Pharm Sci. 2020 Sep;33(5):2143-2151. Pak J Pharm Sci. 2020. PMID: 33824123
The objective of this study is to mask the extremely bitter taste of tilmicosin, and the tilmicosin-resin complex (DRC) microsphere were prepared by entrapping tilmicosin into resins (Tulsion 339 and Eudragit RS/ RL 100) for further pharmacokinetics study in …
The objective of this study is to mask the extremely bitter taste of tilmicosin, and the tilmicosin-resin complex (DRC) micros …
Pharmacokinetic/pharmacodynamic integration of tilmicosin against Pasteurella multocida in a piglet tissue cage model.
Chen Y, Ji X, Zhang S, Wang W, Zhang H, Ding H. Chen Y, et al. Front Vet Sci. 2023 Sep 4;10:1260990. doi: 10.3389/fvets.2023.1260990. eCollection 2023. Front Vet Sci. 2023. PMID: 37732140 Free PMC article.
Tilmicosin is a semi-synthetic macrolide for veterinary use with strong antibacterial effect on respiratory bacteria. ...Concentration of tilmicosin and bacterial numbers of P. multocida in the tissue-cage fluid were monitered. ...
Tilmicosin is a semi-synthetic macrolide for veterinary use with strong antibacterial effect on respiratory bacteria. ...Concentratio …
Tilmicosin modulates the innate immune response and preserves casein production in bovine mammary alveolar cells during Staphylococcus aureus infection.
Martínez-Cortés I, Acevedo-Domínguez NA, Olguin-Alor R, Cortés-Hernández A, Álvarez-Jiménez V, Campillo-Navarro M, Sumano-López HS, Gutiérrez-Olvera L, Martínez-Gómez D, Maravillas-Montero JL, Loor JJ, García-Zepeda EA, Soldevila G. Martínez-Cortés I, et al. J Anim Sci. 2019 Feb 1;97(2):644-656. doi: 10.1093/jas/sky463. J Anim Sci. 2019. PMID: 30517644 Free PMC article.
Pretreatment with tilmicosin increased ERK1/2 (P < 0.05) but decreased P38 phosphorylation (P < 0.01). ...This result indicates that tilmicosin could be an effective modulator inflammation in the mammary gland. ...

Pretreatment with tilmicosin increased ERK1/2 (P < 0.05) but decreased P38 phosphorylation (P < 0.01). ...This result indicates

…
The PK/PD Integration and Resistance of Tilmicosin against Mycoplasma hyopneumoniae.
Huang Z, Hu Z, Zheng H, Xia X, Gu X, Shen X, Yang H, Ding H. Huang Z, et al. Pathogens. 2020 Jun 19;9(6):487. doi: 10.3390/pathogens9060487. Pathogens. 2020. PMID: 32575357 Free PMC article.
The minimum inhibitory concentration (MIC) of tilmicosin against M. hyopneumoniae with an inoculum of 10(6) CFU/mL was 1.6 mug/mL using the microdilution method. ...The area under the concentration-time curve over 96 h divided by the MIC (AUC(0-96 h)/MIC) was the best-fit …
The minimum inhibitory concentration (MIC) of tilmicosin against M. hyopneumoniae with an inoculum of 10(6) CFU/mL was 1.6 mug/mL usi …
611 results