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Results: 1 to 20 of 200

1.

Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma.

Chaudhuri R, McSharry C, Brady J, Grierson C, Messow CM, Spears M, Miele G, Nocka K, MacNee W, Connell M, Murchison JT, Sproule M, Hilmi OJ, Miller DK, Thomson NC.

Eur Respir J. 2014 Jul 3. pii: erj00470-2014. [Epub ahead of print]

PMID:
24993912
[PubMed - as supplied by publisher]
2.

The Effect of Inhaled Interferon-beta on Worsening of Asthma Symptoms Caused by Viral Infections: a Randomised Trial.

Djukanović R, Harrison T, Johnston SL, Gabbay F, Wark P, Thomson NC, Niven R, Singh D, Reddel HK, Davies DE, Marsden R, Boxall C, Dudley S, Plagnol V, Holgate ST, Monk P.

Am J Respir Crit Care Med. 2014 Jun 17. [Epub ahead of print]

PMID:
24937476
[PubMed - as supplied by publisher]
3.

The cost of treating severe refractory asthma in the UK: an economic analysis from the British Thoracic Society Difficult Asthma Registry.

O'Neill S, Sweeney J, Patterson CC, Menzies-Gow A, Niven R, Mansur AH, Bucknall C, Chaudhuri R, Thomson NC, Brightling CE, O'Neill C, Heaney LG; on behalf of the British Thoracic Society Difficult Asthma Network.

Thorax. 2014 Jun 10. pii: thoraxjnl-2013-204114. doi: 10.1136/thoraxjnl-2013-204114. [Epub ahead of print]

PMID:
24917087
[PubMed - as supplied by publisher]
4.

A Randomized trial of an Asthma Internet Self-management Intervention (RAISIN): study protocol for a randomized controlled trial.

Morrison D, Wyke S, Thomson NC, McConnachie A, Agur K, Saunderson K, Chaudhuri R, Mair FS.

Trials. 2014 May 24;15(1):185. doi: 10.1186/1745-6215-15-185.

PMID:
24884722
[PubMed - in process]
Free PMC Article
5.

Novel therapies targeting eosinophilic inflammation in asthma.

Thomson NC.

Clin Exp Allergy. 2014 Apr;44(4):462-8. doi: 10.1111/cea.12268. No abstract available.

PMID:
24666518
[PubMed - in process]
6.

Omalizumab decreases exacerbations and allows a step down in daily inhaled corticosteroid dose in adults and children with moderate-to-severe asthma.

Thomson NC.

Evid Based Med. 2014 Mar 26. doi: 10.1136/eb-2014-101759. [Epub ahead of print] No abstract available.

PMID:
24627175
[PubMed - as supplied by publisher]
7.

Arachidonic acid metabolites and enzyme transcripts in asthma are altered by cigarette smoking.

Thomson NC, Chaudhuri R, Spears M, Messow CM, Jelinsky S, Miele G, Nocka K, Takahashi E, Hilmi OJ, Shepherd MC, Miller DK, McSharry C.

Allergy. 2014 Apr;69(4):527-36. doi: 10.1111/all.12376. Epub 2014 Feb 26.

PMID:
24571371
[PubMed - in process]
8.

Digital asthma self-management interventions: a systematic review.

Morrison D, Wyke S, Agur K, Cameron EJ, Docking RI, Mackenzie AM, McConnachie A, Raghuvir V, Thomson NC, Mair FS.

J Med Internet Res. 2014 Feb 18;16(2):e51. doi: 10.2196/jmir.2814. Review.

PMID:
24550161
[PubMed - in process]
Free PMC Article
9.

Effects of a FLAP inhibitor, GSK2190915, in asthmatics with high sputum neutrophils.

Chaudhuri R, Norris V, Kelly K, Zhu CQ, Ambery C, Lafferty J, Cameron E, Thomson NC.

Pulm Pharmacol Ther. 2014 Feb;27(1):62-9. doi: 10.1016/j.pupt.2013.11.007. Epub 2013 Dec 10.

PMID:
24333186
[PubMed - in process]
10.

Disconnect between sputum neutrophils and other measures of airway inflammation in asthma.

Arron JR, Choy DF, Laviolette M, Kelsen SG, Hatab A, Leigh R, Thomson NC, Bleecker ER, Olivenstein R, Avila PC, Jarjour NN, Castro M, Gauvreau GM, Good JT, Kline JN, Mansur A, Mayers I, Heaney LG, Hamid Q, Harris JM.

Eur Respir J. 2014 Feb;43(2):627-9. doi: 10.1183/09031936.00117013. Epub 2013 Oct 31. No abstract available.

PMID:
24176993
[PubMed - in process]
11.

Inhaled corticosteroids for asthma: on-demand or continuous use.

Thomson NC, Spears M.

Expert Rev Respir Med. 2013 Dec;7(6):687-99. doi: 10.1586/17476348.2013.836062. Epub 2013 Oct 22. Review.

PMID:
24147563
[PubMed - indexed for MEDLINE]
12.

Safety of bronchial thermoplasty in patients with severe refractory asthma.

Pavord ID, Thomson NC, Niven RM, Corris PA, Chung KF, Cox G, Armstrong B, Shargill NS, Laviolette M; Research in Severe Asthma Trial Study Group.

Ann Allergy Asthma Immunol. 2013 Nov;111(5):402-7. doi: 10.1016/j.anai.2013.05.002. Epub 2013 Jun 13.

PMID:
24125149
[PubMed - indexed for MEDLINE]
13.

Randomised controlled trial of azithromycin in smokers with asthma.

Cameron EJ, Chaudhuri R, Mair F, McSharry C, Greenlaw N, Weir CJ, Jolly L, Donnelly I, Gallacher K, Morrison D, Spears M, Evans TJ, Anderson K, Thomson NC.

Eur Respir J. 2013 Nov;42(5):1412-5. doi: 10.1183/09031936.00093913. Epub 2013 Sep 13. No abstract available.

PMID:
24036246
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma.

Wechsler ME, Laviolette M, Rubin AS, Fiterman J, Lapa e Silva JR, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Hales JB, McEvoy C, Slebos DJ, Holmes M, Phillips MJ, Erzurum SC, Hanania NA, Sumino K, Kraft M, Cox G, Sterman DH, Hogarth K, Kline JN, Mansur AH, Louie BE, Leeds WM, Barbers RG, Austin JH, Shargill NS, Quiring J, Armstrong B, Castro M; Asthma Intervention Research 2 Trial Study Group.

J Allergy Clin Immunol. 2013 Dec;132(6):1295-302. doi: 10.1016/j.jaci.2013.08.009. Epub 2013 Aug 30.

PMID:
23998657
[PubMed - indexed for MEDLINE]
15.

Smoking in asthma is associated with elevated levels of corticosteroid resistant sputum cytokines-an exploratory study.

Spears M, McSharry C, Chaudhuri R, Weir CJ, de Wet C, Thomson NC.

PLoS One. 2013 Aug 9;8(8):e71460. doi: 10.1371/journal.pone.0071460. eCollection 2013.

PMID:
23951170
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Characterization and validation of an isotope-dilution LC-MS/MS method for quantification of total desmosine and isodesmosine in plasma and serum.

Albarbarawi O, Barton A, Miller D, McSharry C, Chaudhuri R, Thomson NC, Palmer CN, Devereux G, Huang JT.

Bioanalysis. 2013 Aug;5(16):1991-2001. doi: 10.4155/bio.13.164.

PMID:
23937134
[PubMed - in process]
17.

Chronic cough and sputum production are associated with worse clinical outcomes in stable asthma.

Thomson NC, Chaudhuri R, Messow CM, Spears M, MacNee W, Connell M, Murchison JT, Sproule M, McSharry C.

Respir Med. 2013 Oct;107(10):1501-8. doi: 10.1016/j.rmed.2013.07.017. Epub 2013 Aug 6.

PMID:
23927851
[PubMed - indexed for MEDLINE]
Free Article
18.

Clinical outcomes and inflammatory biomarkers in current smokers and exsmokers with severe asthma.

Thomson NC, Chaudhuri R, Heaney LG, Bucknall C, Niven RM, Brightling CE, Menzies-Gow AN, Mansur AH, McSharry C.

J Allergy Clin Immunol. 2013 Apr;131(4):1008-16. doi: 10.1016/j.jaci.2012.12.1574. Epub 2013 Feb 16.

PMID:
23419540
[PubMed - indexed for MEDLINE]
19.

Lebrikizumab in the personalized management of asthma.

Thomson NC, Patel M, Smith AD.

Biologics. 2012;6:329-35. doi: 10.2147/BTT.S28666. Epub 2012 Sep 14.

PMID:
23055690
[PubMed]
Free PMC Article
20.

Long-term macrolide treatment of chronic inflammatory airway diseases: risks, benefits and future developments.

Cameron EJ, McSharry C, Chaudhuri R, Farrow S, Thomson NC.

Clin Exp Allergy. 2012 Sep;42(9):1302-12. doi: 10.1111/j.1365-2222.2012.03979.x. Review.

PMID:
22925316
[PubMed - indexed for MEDLINE]

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