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Results: 1 to 20 of 68

1.

Functional Metabolic Map of Faecalibacterium prausnitzii, a Beneficial Human Gut Microbe.

Heinken A, Khan MT, Paglia G, Rodionov DA, Harmsen HJ, Thiele I.

J Bacteriol. 2014 Sep 15;196(18):3289-302. doi: 10.1128/JB.01780-14. Epub 2014 Jul 7.

PMID:
25002542
[PubMed - in process]
2.

Genome-Scale Methods Converge on Key Mitochondrial Genes for the Survival of Human Cardiomyocytes in Hypoxia.

Edwards LM, Sigurdsson MI, Robbins PA, Weale ME, Cavalleri GL, Montgomery HE, Thiele I.

Circ Cardiovasc Genet. 2014 May 29. pii: CIRCGENETICS.113.000269. [Epub ahead of print]

PMID:
24873932
[PubMed - as supplied by publisher]
3.

fastGapFill: efficient gap filling in metabolic networks.

Thiele I, Vlassis N, Fleming RM.

Bioinformatics. 2014 May 7. pii: btu321. [Epub ahead of print]

PMID:
24812336
[PubMed - as supplied by publisher]
Free Article
4.

Membrane transporters in a human genome-scale metabolic knowledgebase and their implications for disease.

Sahoo S, Aurich MK, Jonsson JJ, Thiele I.

Front Physiol. 2014 Mar 11;5:91. doi: 10.3389/fphys.2014.00091. eCollection 2014. Review.

PMID:
24653705
[PubMed]
Free PMC Article
5.

Phospholipase A2 receptor autoantibodies and clinical outcome in patients with primary membranous nephropathy.

Hoxha E, Thiele I, Zahner G, Panzer U, Harendza S, Stahl RA.

J Am Soc Nephrol. 2014 Jun;25(6):1357-66. doi: 10.1681/ASN.2013040430. Epub 2014 Mar 7.

PMID:
24610926
[PubMed - in process]
6.

Comparative evaluation of open source software for mapping between metabolite identifiers in metabolic network reconstructions: application to Recon 2.

Haraldsdóttir HS, Thiele I, Fleming RM.

J Cheminform. 2014 Jan 27;6(1):2. doi: 10.1186/1758-2946-6-2.

PMID:
24468196
[PubMed]
Free PMC Article
7.

Robust flux balance analysis of multiscale biochemical reaction networks.

Sun Y, Fleming RM, Thiele I, Saunders MA.

BMC Bioinformatics. 2013 Jul 30;14:240. doi: 10.1186/1471-2105-14-240.

PMID:
23899245
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Applying systems biology methods to the study of human physiology in extreme environments.

Edwards LM, Thiele I.

Extrem Physiol Med. 2013 Mar 22;2(1):8. doi: 10.1186/2046-7648-2-8.

PMID:
23849719
[PubMed]
Free PMC Article
9.

Consensus and conflict cards for metabolic pathway databases.

Stobbe MD, Swertz MA, Thiele I, Rengaw T, van Kampen AH, Moerland PD.

BMC Syst Biol. 2013 Jun 26;7:50. doi: 10.1186/1752-0509-7-50.

PMID:
23803311
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Predicting the impact of diet and enzymopathies on human small intestinal epithelial cells.

Sahoo S, Thiele I.

Hum Mol Genet. 2013 Jul 1;22(13):2705-22. doi: 10.1093/hmg/ddt119. Epub 2013 Mar 13.

PMID:
23492669
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

A community-driven global reconstruction of human metabolism.

Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, Dobson P, Dunn WB, Endler L, Hala D, Hucka M, Hull D, Jameson D, Jamshidi N, Jonsson JJ, Juty N, Keating S, Nookaew I, Le Novère N, Malys N, Mazein A, Papin JA, Price ND, Selkov E Sr, Sigurdsson MI, Simeonidis E, Sonnenschein N, Smallbone K, Sorokin A, van Beek JH, Weichart D, Goryanin I, Nielsen J, Westerhoff HV, Kell DB, Mendes P, Palsson BØ.

Nat Biotechnol. 2013 May;31(5):419-25. doi: 10.1038/nbt.2488. Epub 2013 Mar 3.

PMID:
23455439
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Contextualization procedure and modeling of monocyte specific TLR signaling.

Aurich MK, Thiele I.

PLoS One. 2012;7(12):e49978. doi: 10.1371/journal.pone.0049978. Epub 2012 Dec 6.

PMID:
23236359
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Toward systems metabolic engineering in cyanobacteria: opportunities and bottlenecks.

Nogales J, Gudmundsson S, Thiele I.

Bioengineered. 2013 May-Jun;4(3):158-63. doi: 10.4161/bioe.22792. Epub 2012 Nov 8.

PMID:
23138691
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A systems biology approach to studying the role of microbes in human health.

Thiele I, Heinken A, Fleming RM.

Curr Opin Biotechnol. 2013 Feb;24(1):4-12. doi: 10.1016/j.copbio.2012.10.001. Epub 2012 Oct 25. Review.

PMID:
23102866
[PubMed - indexed for MEDLINE]
15.

Inferring the metabolism of human orphan metabolites from their metabolic network context affirms human gluconokinase activity.

Rolfsson Ó, Paglia G, Magnusdóttir M, Palsson BØ, Thiele I.

Biochem J. 2013 Jan 15;449(2):427-35. doi: 10.1042/BJ20120980.

PMID:
23067238
[PubMed - indexed for MEDLINE]
Free Article
16.

Multiscale modeling of metabolism and macromolecular synthesis in E. coli and its application to the evolution of codon usage.

Thiele I, Fleming RM, Que R, Bordbar A, Diep D, Palsson BO.

PLoS One. 2012;7(9):e45635. doi: 10.1371/journal.pone.0045635. Epub 2012 Sep 28.

PMID:
23029152
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Systems-level characterization of a host-microbe metabolic symbiosis in the mammalian gut.

Heinken A, Sahoo S, Fleming RM, Thiele I.

Gut Microbes. 2013 Jan-Feb;4(1):28-40. doi: 10.4161/gmic.22370. Epub 2012 Sep 28.

PMID:
23022739
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mass conserved elementary kinetics is sufficient for the existence of a non-equilibrium steady state concentration.

Fleming RM, Thiele I.

J Theor Biol. 2012 Dec 7;314:173-81. doi: 10.1016/j.jtbi.2012.08.021. Epub 2012 Aug 28.

PMID:
22947275
[PubMed - indexed for MEDLINE]
19.

Quantitative assignment of reaction directionality in a multicompartmental human metabolic reconstruction.

Haraldsdóttir HS, Thiele I, Fleming RM.

Biophys J. 2012 Apr 18;102(8):1703-11. doi: 10.1016/j.bpj.2012.02.032.

PMID:
22768925
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A compendium of inborn errors of metabolism mapped onto the human metabolic network.

Sahoo S, Franzson L, Jonsson JJ, Thiele I.

Mol Biosyst. 2012 Oct;8(10):2545-58. doi: 10.1039/c2mb25075f.

PMID:
22699794
[PubMed - indexed for MEDLINE]

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