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Beta thalassaemia intermedia due to co-inheritance of three unique alpha globin cluster duplications characterised by next generation sequencing analysis.

Clark B, Shooter C, Smith F, Brawand D, Steedman L, Oakley M, Rushton P, Rooks H, Wang X, Drousiotou A, Kyrri A, Hadjigavriel M, Will A, Fisher C, Higgs DR, Phylipsen M, Harteveld C, Kleanthous M, Thein SL.

Br J Haematol. 2016 Jul 29. doi: 10.1111/bjh.14294. [Epub ahead of print] No abstract available.


Survival in adults with sickle cell disease in a high-income setting.

Gardner K, Douiri A, Drasar E, Allman M, Mwirigi A, Awogbade M, Thein SL.

Blood. 2016 Jul 20. pii: blood-2016-05-716910. [Epub ahead of print] No abstract available.


ASH1L (a histone methyltransferase protein) is a novel candidate globin gene regulator revealed by genetic study of an English family with beta-thalassaemia unlinked to the beta-globin locus.

Breton A, Theodorou A, Aktuna S, Sonzogni L, Darling D, Chan L, Menzel S, van der Spek PJ, Swagemakers SM, Grosveld F, Philipsen S, Thein SL.

Br J Haematol. 2016 Jul 19. doi: 10.1111/bjh.14256. [Epub ahead of print]


Who continues to stock oral artemisinin monotherapy? Results of a provider survey in Myanmar.

Thein ST, Sudhinaraset M, Khin HS, McFarland W, Aung T.

Malar J. 2016 Jun 22;15:334. doi: 10.1186/s12936-016-1392-5.


Intracranial Aneurysms in Sickle-Cell Disease Are Associated With the Hemoglobin SS Genotype But Not With Moyamoya Syndrome.

Birkeland P, Gardner K, Kesse-Adu R, Davies J, Lauritsen J, Rom Poulsen F, Tolias CM, Thein SL.

Stroke. 2016 Jul;47(7):1710-3. doi: 10.1161/STROKEAHA.116.012664. Epub 2016 Jun 14.


The investigation of resveratrol and analogs as potential inducers of fetal hemoglobin.

Theodorou A, Phylactides M, Forti L, Cramarossa MR, Spyrou P, Gambari R, Thein SL, Kleanthous M.

Blood Cells Mol Dis. 2016 May;58:6-12. doi: 10.1016/j.bcmd.2015.11.007. Epub 2015 Dec 1.


Effects of strength training program on hip extensors and knee extensors strength of lower limb in children with spastic diplegic cerebral palsy.

Aye T, Thein S, Hlaing T.

J Phys Ther Sci. 2016 Jan;28(2):671-6. doi: 10.1589/jpts.28.671. Epub 2016 Feb 29.


Alpha-thalassaemia trait as a cause of unexplained microcytosis in a South African population.

Loonat SB, Naran NH, Thein SL, Alli NA.

S Afr Med J. 2016 Feb 22;106(3):276-9. doi: 10.7196/SAMJ.2016.v106i3.10005.


Reduced rate of sickle-related complications in Brazilian patients carrying HbF-promoting alleles at the BCL11A and HMIP-2 loci.

Leonardo FC, Brugnerotto AF, Domingos IF, Fertrin KY, de Albuquerque DM, Bezerra MA, Araújo AS, Saad ST, Costa FF, Menzel S, Conran N, Thein SL.

Br J Haematol. 2016 May;173(3):456-60. doi: 10.1111/bjh.13961. Epub 2016 Feb 16.


The European Hematology Association Roadmap for European Hematology Research: a consensus document.

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, de Wit TD, Eichinger S, Fibbe W, Green T, de Haas F, Iolascon A, Jaffredo T, Rodeghiero F, Salles G, Schuringa JJ; EHA Roadmap for European Hematology Research.

Haematologica. 2016 Feb;101(2):115-208. doi: 10.3324/haematol.2015.136739. Epub 2016 Jan 27.


Longitudinal assessment of lung function in children with sickle cell disease.

Lunt A, McGhee E, Sylvester K, Rafferty G, Dick M, Rees D, Height S, Thein SL, Greenough A.

Pediatr Pulmonol. 2016 Jul;51(7):717-23. doi: 10.1002/ppul.23367. Epub 2015 Dec 22.


Airway and alveolar nitric oxide production, lung function, and pulmonary blood flow in sickle cell disease.

Lunt A, Ahmed N, Rafferty GF, Dick M, Rees D, Height S, Thein SL, Greenough A.

Pediatr Res. 2016 Feb;79(2):313-7. doi: 10.1038/pr.2015.217. Epub 2015 Oct 22.


Venous thromboembolism in adults with sickle cell disease: experience of a single centre in the UK.

van Hamel Parsons V, Gardner K, Patel R, Thein SL.

Ann Hematol. 2016 Jan;95(2):227-32.


Seroadaptive Behaviors of Men Who Have Sex with Men in Myanmar.

Aung T, Thein ST, McFarland W.

AIDS Behav. 2015 Oct 7. [Epub ahead of print]


Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.

Coric V, Salloway S, van Dyck CH, Dubois B, Andreasen N, Brody M, Curtis C, Soininen H, Thein S, Shiovitz T, Pilcher G, Ferris S, Colby S, Kerselaers W, Dockens R, Soares H, Kaplita S, Luo F, Pachai C, Bracoud L, Mintun M, Grill JD, Marek K, Seibyl J, Cedarbaum JM, Albright C, Feldman HH, Berman RM.

JAMA Neurol. 2015 Nov;72(11):1324-33. doi: 10.1001/jamaneurol.2015.0607.


Tissue Iron Distribution Assessed by MRI in Patients with Iron Loading Anemias.

Gutiérrez L, House MJ, Vasavda N, Drašar E, Gonzalez-Gascon Y Marin I, Kulasekararaj AG, St Pierre TG, Thein SL.

PLoS One. 2015 Sep 25;10(9):e0139220. doi: 10.1371/journal.pone.0139220. eCollection 2015.


Genome-wide association analyses based on whole-genome sequencing in Sardinia provide insights into regulation of hemoglobin levels.

Danjou F, Zoledziewska M, Sidore C, Steri M, Busonero F, Maschio A, Mulas A, Perseu L, Barella S, Porcu E, Pistis G, Pitzalis M, Pala M, Menzel S, Metrustry S, Spector TD, Leoni L, Angius A, Uda M, Moi P, Thein SL, Galanello R, Abecasis GR, Schlessinger D, Sanna S, Cucca F.

Nat Genet. 2015 Nov;47(11):1264-71. doi: 10.1038/ng.3307. Epub 2015 Sep 14.


Prevention of Morbidity in sickle cell disease--qualitative outcomes, pain and quality of life in a randomised cross-over pilot trial of overnight supplementary oxygen and auto-adjusting continuous positive airways pressure (POMS2a): study protocol for a randomised controlled trial.

Howard J, Inusa B, Liossi C, Jacob E, Murphy PB, Hart N, Gavlak J, Sahota S, Chorozoglou M, Nwosu C, Gwam M, Gupta A, Rees DC, Thein SL, Reading IC, Kirkham FJ, Cheng MY.

Trials. 2015 Aug 25;16:376. doi: 10.1186/s13063-015-0883-y.


Pulmonary Haemodynamics in Sickle Cell Disease Are Driven Predominantly by a High-Output State Rather Than Elevated Pulmonary Vascular Resistance: A Prospective 3-Dimensional Echocardiography/Doppler Study.

Mushemi-Blake S, Melikian N, Drasar E, Bhan A, Lunt A, Desai SR, Greenough A, Monaghan MJ, Thein SL, Shah AM.

PLoS One. 2015 Aug 13;10(8):e0135472. doi: 10.1371/journal.pone.0135472. eCollection 2015.


Estimation of the number of female sex workers in Yangon and Mandalay, Myanmar.

Thein ST, Aung T, McFarland W.

AIDS Behav. 2015 Oct;19(10):1941-7. doi: 10.1007/s10461-015-1169-9.

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