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Results: 1 to 20 of 30

1.

Assay to probe proteolytic processing of Notch by γ-secretase.

Serneels L, Tesseur I, De Strooper B.

Methods Mol Biol. 2014;1187:223-9. doi: 10.1007/978-1-4939-1139-4_17.

PMID:
25053493
2.

Regulation of amyloid precursor protein processing by serotonin signaling.

Pimenova AA, Thathiah A, De Strooper B, Tesseur I.

PLoS One. 2014 Jan 21;9(1):e87014. doi: 10.1371/journal.pone.0087014. eCollection 2014.

3.

When the dust settles: what did we learn from the bexarotene discussion?

Tesseur I, De Strooper B.

Alzheimers Res Ther. 2013 Nov 7;5(6):54. doi: 10.1186/alzrt218. eCollection 2013.

4.

Dose-dependent improvements in learning and memory deficits in APPPS1-21 transgenic mice treated with the orally active Aβ toxicity inhibitor SEN1500.

Lo AC, Tesseur I, Scopes DI, Nerou E, Callaerts-Vegh Z, Vermaercke B, Treherne JM, De Strooper B, D'Hooge R.

Neuropharmacology. 2013 Dec;75:458-66. doi: 10.1016/j.neuropharm.2013.08.030. Epub 2013 Sep 10.

PMID:
24035915
5.

Amyloid and tau neuropathology differentially affect prefrontal synaptic plasticity and cognitive performance in mouse models of Alzheimer's disease.

Lo AC, Iscru E, Blum D, Tesseur I, Callaerts-Vegh Z, Buée L, De Strooper B, Balschun D, D'Hooge R.

J Alzheimers Dis. 2013;37(1):109-25. doi: 10.3233/JAD-122296.

PMID:
23788007
6.

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

Tesseur I, Lo AC, Roberfroid A, Dietvorst S, Van Broeck B, Borgers M, Gijsen H, Moechars D, Mercken M, Kemp J, D'Hooge R, De Strooper B.

Science. 2013 May 24;340(6135):924-e. doi: 10.1126/science.1233937.

7.

Chronic 5-HT4 receptor activation decreases Aβ production and deposition in hAPP/PS1 mice.

Tesseur I, Pimenova AA, Lo AC, Ciesielska M, Lichtenthaler SF, De Maeyer JH, Schuurkes JA, D'Hooge R, De Strooper B.

Neurobiol Aging. 2013 Jul;34(7):1779-89. doi: 10.1016/j.neurobiolaging.2013.01.020. Epub 2013 Mar 6.

PMID:
23474291
8.

ADAM9 inhibition increases membrane activity of ADAM10 and controls α-secretase processing of amyloid precursor protein.

Moss ML, Powell G, Miller MA, Edwards L, Qi B, Sang QX, De Strooper B, Tesseur I, Lichtenthaler SF, Taverna M, Zhong JL, Dingwall C, Ferdous T, Schlomann U, Zhou P, Griffith LG, Lauffenburger DA, Petrovich R, Bartsch JW.

J Biol Chem. 2011 Nov 25;286(47):40443-51. doi: 10.1074/jbc.M111.280495. Epub 2011 Sep 28.

9.

The disintegrin/metalloproteinase ADAM10 is essential for the establishment of the brain cortex.

Jorissen E, Prox J, Bernreuther C, Weber S, Schwanbeck R, Serneels L, Snellinx A, Craessaerts K, Thathiah A, Tesseur I, Bartsch U, Weskamp G, Blobel CP, Glatzel M, De Strooper B, Saftig P.

J Neurosci. 2010 Apr 7;30(14):4833-44. doi: 10.1523/JNEUROSCI.5221-09.2010.

10.

Bioactive TGF-beta can associate with lipoproteins and is enriched in those containing apolipoprotein E3.

Tesseur I, Zhang H, Brecht W, Corn J, Gong JS, Yanagisawa K, Michikawa M, Weisgraber K, Huang Y, Wyss-Coray T.

J Neurochem. 2009 Aug;110(4):1254-62. doi: 10.1111/j.1471-4159.2009.06222.x. Epub 2009 Jun 15.

11.

Collagen VI protects neurons against Abeta toxicity.

Cheng JS, Dubal DB, Kim DH, Legleiter J, Cheng IH, Yu GQ, Tesseur I, Wyss-Coray T, Bonaldo P, Mucke L.

Nat Neurosci. 2009 Feb;12(2):119-21. doi: 10.1038/nn.2240. Epub 2009 Jan 4.

12.

Genes contributing to prion pathogenesis.

Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB.

J Gen Virol. 2008 Jul;89(Pt 7):1777-88. doi: 10.1099/vir.0.2008/001255-0.

13.

A role for TGF-beta signaling in neurodegeneration: evidence from genetically engineered models.

Tesseur I, Wyss-Coray T.

Curr Alzheimer Res. 2006 Dec;3(5):505-13. Review.

PMID:
17168649
14.

Deficiency in neuronal TGF-beta signaling promotes neurodegeneration and Alzheimer's pathology.

Tesseur I, Zou K, Esposito L, Bard F, Berber E, Can JV, Lin AH, Crews L, Tremblay P, Mathews P, Mucke L, Masliah E, Wyss-Coray T.

J Clin Invest. 2006 Nov;116(11):3060-9.

15.

Highly sensitive and specific bioassay for measuring bioactive TGF-beta.

Tesseur I, Zou K, Berber E, Zhang H, Wyss-Coray T.

BMC Cell Biol. 2006 Mar 20;7:15.

16.

Small molecule tgf-beta mimetics as potential neuroprotective factors.

Zhang H, Zou K, Tesseur I, Wyss-Coray T.

Curr Alzheimer Res. 2005 Apr;2(2):183-6.

PMID:
15974916
17.

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

Brecht WJ, Harris FM, Chang S, Tesseur I, Yu GQ, Xu Q, Dee Fish J, Wyss-Coray T, Buttini M, Mucke L, Mahley RW, Huang Y.

J Neurosci. 2004 Mar 10;24(10):2527-34.

18.

Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain.

Brionne TC, Tesseur I, Masliah E, Wyss-Coray T.

Neuron. 2003 Dec 18;40(6):1133-45.

PMID:
14687548
19.

Astroglial regulation of apolipoprotein E expression in neuronal cells. Implications for Alzheimer's disease.

Harris FM, Tesseur I, Brecht WJ, Xu Q, Mullendorff K, Chang S, Wyss-Coray T, Mahley RW, Huang Y.

J Biol Chem. 2004 Jan 30;279(5):3862-8. Epub 2003 Oct 29.

20.

Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice.

Harris FM, Brecht WJ, Xu Q, Tesseur I, Kekonius L, Wyss-Coray T, Fish JD, Masliah E, Hopkins PC, Scearce-Levie K, Weisgraber KH, Mucke L, Mahley RW, Huang Y.

Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10966-71. Epub 2003 Aug 25.

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