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Results: 1 to 20 of 68


Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer.

Banerji CR, Severini S, Caldas C, Teschendorff AE.

PLoS Comput Biol. 2015 Mar 20;11(3):e1004115. doi: 10.1371/journal.pcbi.1004115. eCollection 2015 Mar.


An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging.

Yuan T, Jiao Y, de Jong S, Ophoff RA, Beck S, Teschendorff AE.

PLoS Genet. 2015 Feb 18;11(2):e1004996. doi: 10.1371/journal.pgen.1004996. eCollection 2015 Feb.


β-Catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy.

Banerji CR, Knopp P, Moyle LA, Severini S, Orrell RW, Teschendorff AE, Zammit PS.

J R Soc Interface. 2015 Jan 6;12(102):20140797.


Biomedical data integration, modeling, and simulation in the era of big data and translational medicine.

Shen B, Teschendorff AE, Zhi D, Xia J.

Biomed Res Int. 2014;2014:731546. doi: 10.1155/2014/731546. Epub 2014 Jul 24. No abstract available.


A BRCA1-mutation associated DNA methylation signature in blood cells predicts sporadic breast cancer incidence and survival.

Anjum S, Fourkala EO, Zikan M, Wong A, Gentry-Maharaj A, Jones A, Hardy R, Cibula D, Kuh D, Jacobs IJ, Teschendorff AE, Menon U, Widschwendter M.

Genome Med. 2014 Jun 27;6(6):47. doi: 10.1186/gm567. eCollection 2014.


The dynamics of DNA methylation covariation patterns in carcinogenesis.

Teschendorff AE, Liu X, Caren H, Pollard SM, Beck S, Widschwendter M, Chen L.

PLoS Comput Biol. 2014 Jul 10;10(7):e1003709. doi: 10.1371/journal.pcbi.1003709. eCollection 2014 Jul.


Comparisons of non-Gaussian statistical models in DNA methylation analysis.

Ma Z, Teschendorff AE, Yu H, Taghia J, Guo J.

Int J Mol Sci. 2014 Jun 16;15(6):10835-54. doi: 10.3390/ijms150610835.


A systems-level integrative framework for genome-wide DNA methylation and gene expression data identifies differential gene expression modules under epigenetic control.

Jiao Y, Widschwendter M, Teschendorff AE.

Bioinformatics. 2014 Aug 15;30(16):2360-6. doi: 10.1093/bioinformatics/btu316. Epub 2014 May 2.


Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.

Steegenga WT, Boekschoten MV, Lute C, Hooiveld GJ, de Groot PJ, Morris TJ, Teschendorff AE, Butcher LM, Beck S, Müller M.

Age (Dordr). 2014 Jun;36(3):9648. doi: 10.1007/s11357-014-9648-x. Epub 2014 May 2.


Signalling entropy: A novel network-theoretical framework for systems analysis and interpretation of functional omic data.

Teschendorff AE, Sollich P, Kuehn R.

Methods. 2014 Jun 1;67(3):282-93. doi: 10.1016/j.ymeth.2014.03.013. Epub 2014 Mar 24.


JAK2-centered interactome hotspot identified by an integrative network algorithm in acute Stanford type A aortic dissection.

Pan S, Wu D, Teschendorff AE, Hong T, Wang L, Qian M, Wang C, Wang X.

PLoS One. 2014 Feb 24;9(2):e89406. doi: 10.1371/journal.pone.0089406. eCollection 2014.


Using high-density DNA methylation arrays to profile copy number alterations.

Feber A, Guilhamon P, Lechner M, Fenton T, Wilson GA, Thirlwell C, Morris TJ, Flanagan AM, Teschendorff AE, Kelly JD, Beck S.

Genome Biol. 2014 Feb 3;15(2):R30. doi: 10.1186/gb-2014-15-2-r30.


ChAMP: 450k Chip Analysis Methylation Pipeline.

Morris TJ, Butcher LM, Feber A, Teschendorff AE, Chakravarthy AR, Wojdacz TK, Beck S.

Bioinformatics. 2014 Feb 1;30(3):428-30. doi: 10.1093/bioinformatics/btt684. Epub 2013 Dec 12.


Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development.

Jones A, Teschendorff AE, Li Q, Hayward JD, Kannan A, Mould T, West J, Zikan M, Cibula D, Fiegl H, Lee SH, Wik E, Hadwin R, Arora R, Lemech C, Turunen H, Pakarinen P, Jacobs IJ, Salvesen HB, Bagchi MK, Bagchi IC, Widschwendter M.

PLoS Med. 2013 Nov;10(11):e1001551. doi: 10.1371/journal.pmed.1001551. Epub 2013 Nov 12.


Cellular network entropy as the energy potential in Waddington's differentiation landscape.

Banerji CR, Miranda-Saavedra D, Severini S, Widschwendter M, Enver T, Zhou JX, Teschendorff AE.

Sci Rep. 2013 Oct 24;3:3039. doi: 10.1038/srep03039.


Epigenetic aging: insights from network biology.

Teschendorff AE.

Aging (Albany NY). 2013 Oct;5(10):719-20. No abstract available.


Distinctive topology of age-associated epigenetic drift in the human interactome.

West J, Widschwendter M, Teschendorff AE.

Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14138-43. doi: 10.1073/pnas.1307242110. Epub 2013 Aug 12.


Age-associated epigenetic drift: implications, and a case of epigenetic thrift?

Teschendorff AE, West J, Beck S.

Hum Mol Genet. 2013 Oct 15;22(R1):R7-R15. doi: 10.1093/hmg/ddt375. Epub 2013 Aug 4. Review.


Corruption of the intra-gene DNA methylation architecture is a hallmark of cancer.

Bartlett TE, Zaikin A, Olhede SC, West J, Teschendorff AE, Widschwendter M.

PLoS One. 2013 Jul 16;8(7):e68285. doi: 10.1371/journal.pone.0068285. Print 2013.

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