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Results: 1 to 20 of 71

1.

Accelerating translational research by clinically driven development of an informatics platform-a case study.

Abugessaisa I, Saevarsdottir S, Tsipras G, Lindblad S, Sandin C, Nikamo P, Ståhle M, Malmström V, Klareskog L, Tegnér J.

PLoS One. 2014 Sep 9;9(9):e104382. doi: 10.1371/journal.pone.0104382. eCollection 2014.

PMID:
25203647
[PubMed - in process]
Free PMC Article
2.

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

Snir O, Gomez-Cabrero D, Montes A, Perez-Pampin E, Gómez-Reino JJ, Seddighzadeh M, Klich KU, Israelsson L, Ding B, Catrina AI, Holmdahl R, Alfredsson L, Klareskog L, Tegnér J, Gonzalez A, Malmström V, Padyukov L.

Arthritis Res Ther. 2014 Aug 20;16(5):414. [Epub ahead of print]

PMID:
25138370
[PubMed - as supplied by publisher]
3.

Signaling networks in MS: A systems-based approach to developing new pharmacological therapies.

Kotelnikova E, Bernardo-Faura M, Silberberg G, Kiani NA, Messinis D, Melas IN, Artigas L, Schwartz E, Mazo I, Masso M, Alexopoulos LG, Mas JM, Olsson T, Tegner J, Martin R, Zamora A, Paul F, Saez-Rodriguez J, Villoslada P.

Mult Scler. 2014 Aug 11. pii: 1352458514543339. [Epub ahead of print]

PMID:
25112814
[PubMed - as supplied by publisher]
4.

STATegra EMS: an Experiment Management System for complex next-generation omics experiments.

Hernández-de-Diego R, Boix-Chova N, Gómez-Cabrero D, Tegner J, Abugessaisa I, Conesa A.

BMC Syst Biol. 2014;8 Suppl 2:S9. doi: 10.1186/1752-0509-8-S2-S9. Epub 2014 Mar 13.

PMID:
25033091
[PubMed - in process]
Free PMC Article
5.

Data integration in the era of omics: current and future challenges.

Gomez-Cabrero D, Abugessaisa I, Maier D, Teschendorff A, Merkenschlager M, Gisel A, Ballestar E, Bongcam-Rudloff E, Conesa A, Tegnér J.

BMC Syst Biol. 2014;8 Suppl 2:I1. doi: 10.1186/1752-0509-8-S2-I1. Epub 2014 Mar 13.

PMID:
25032990
[PubMed - in process]
Free PMC Article
6.

A vision and strategy for the virtual physiological human: 2012 update.

Hunter P, Chapman T, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Shublaq N, Skår J, Stroetmann K, Tegner J, Thomas SR, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Interface Focus. 2013 Apr 6;3(2):20130004. doi: 10.1098/rsfs.2013.0004.

PMID:
24427536
[PubMed]
Free PMC Article
7.

Importance of mitochondrial P(O2) in maximal O2 transport and utilization: a theoretical analysis.

Cano I, Mickael M, Gomez-Cabrero D, Tegnér J, Roca J, Wagner PD.

Respir Physiol Neurobiol. 2013 Dec 1;189(3):477-83. doi: 10.1016/j.resp.2013.08.020. Epub 2013 Sep 5.

PMID:
24012990
[PubMed - indexed for MEDLINE]
8.

Implementation of the CDC translational informatics platform--from genetic variants to the national Swedish Rheumatology Quality Register.

Abugessaisa I, Gomez-Cabrero D, Snir O, Lindblad S, Klareskog L, Malmström V, Tegnér J.

J Transl Med. 2013 Apr 2;11:85. doi: 10.1186/1479-5876-11-85.

PMID:
23548156
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform.

Marabita F, Almgren M, Lindholm ME, Ruhrmann S, Fagerström-Billai F, Jagodic M, Sundberg CJ, Ekström TJ, Teschendorff AE, Tegnér J, Gomez-Cabrero D.

Epigenetics. 2013 Mar;8(3):333-46. doi: 10.4161/epi.24008. Epub 2013 Feb 19.

PMID:
23422812
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pediatric systems medicine: evaluating needs and opportunities using congenital heart block as a case study.

Tegnér J, Abugessaisa I.

Pediatr Res. 2013 Apr;73(4 Pt 2):508-13. doi: 10.1038/pr.2013.19. Epub 2013 Jan 31. Review.

PMID:
23370412
[PubMed - indexed for MEDLINE]
11.

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression.

de la Rica L, Urquiza JM, Gómez-Cabrero D, Islam AB, López-Bigas N, Tegnér J, Toes RE, Ballestar E.

J Autoimmun. 2013 Mar;41:6-16. doi: 10.1016/j.jaut.2012.12.005. Epub 2013 Jan 8.

PMID:
23306098
[PubMed - indexed for MEDLINE]
12.

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.

Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D, Beck S.

Bioinformatics. 2013 Jan 15;29(2):189-96. doi: 10.1093/bioinformatics/bts680. Epub 2012 Nov 21.

PMID:
23175756
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Workflow for generating competing hypothesis from models with parameter uncertainty.

Gomez-Cabrero D, Compte A, Tegner J.

Interface Focus. 2011 Jun 6;1(3):438-49. doi: 10.1098/rsfs.2011.0015. Epub 2011 Mar 30.

PMID:
22670212
[PubMed]
Free PMC Article
14.

Pre-B cell to macrophage transdifferentiation without significant promoter DNA methylation changes.

Rodríguez-Ubreva J, Ciudad L, Gómez-Cabrero D, Parra M, Bussmann LH, di Tullio A, Kallin EM, Tegnér J, Graf T, Ballestar E.

Nucleic Acids Res. 2012 Mar;40(5):1954-68. doi: 10.1093/nar/gkr1015. Epub 2011 Nov 15.

PMID:
22086955
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Decoding complex biological networks - tracing essential and modulatory parameters in complex and simplified models of the cell cycle.

Eriksson O, Andersson T, Zhou Y, Tegnér J.

BMC Syst Biol. 2011 Aug 7;5:123. doi: 10.1186/1752-0509-5-123.

PMID:
21819620
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systems medicine and integrated care to combat chronic noncommunicable diseases.

Bousquet J, Anto JM, Sterk PJ, Adcock IM, Chung KF, Roca J, Agusti A, Brightling C, Cambon-Thomsen A, Cesario A, Abdelhak S, Antonarakis SE, Avignon A, Ballabio A, Baraldi E, Baranov A, Bieber T, Bockaert J, Brahmachari S, Brambilla C, Bringer J, Dauzat M, Ernberg I, Fabbri L, Froguel P, Galas D, Gojobori T, Hunter P, Jorgensen C, Kauffmann F, Kourilsky P, Kowalski ML, Lancet D, Pen CL, Mallet J, Mayosi B, Mercier J, Metspalu A, Nadeau JH, Ninot G, Noble D, Oztürk M, Palkonen S, Préfaut C, Rabe K, Renard E, Roberts RG, Samolinski B, Schünemann HJ, Simon HU, Soares MB, Superti-Furga G, Tegner J, Verjovski-Almeida S, Wellstead P, Wolkenhauer O, Wouters E, Balling R, Brookes AJ, Charron D, Pison C, Chen Z, Hood L, Auffray C.

Genome Med. 2011 Jul 6;3(7):43. doi: 10.1186/gm259.

PMID:
21745417
[PubMed]
Free PMC Article
17.

ParkDB: a Parkinson's disease gene expression database.

Taccioli C, Tegnér J, Maselli V, Gomez-Cabrero D, Altobelli G, Emmett W, Lescai F, Gustincich S, Stupka E.

Database (Oxford). 2011 May 18;2011:bar007. doi: 10.1093/database/bar007. Print 2011.

PMID:
21593080
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Carotid plaque age is a feature of plaque stability inversely related to levels of plasma insulin.

Hägg S, Salehpour M, Noori P, Lundström J, Possnert G, Takolander R, Konrad P, Rosfors S, Ruusalepp A, Skogsberg J, Tegnér J, Björkegren J.

PLoS One. 2011 Apr 7;6(4):e18248. doi: 10.1371/journal.pone.0018248.

PMID:
21490968
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Blood levels of dual-specificity phosphatase-1 independently predict risk for post-operative morbidities causing prolonged hospitalization after coronary artery bypass grafting.

Hägg S, Alserius T, Noori P, Ruusalepp A, Ivert T, Tegnér J, Björkegren J, Skogsberg J.

Int J Mol Med. 2011 Jun;27(6):851-7. doi: 10.3892/ijmm.2011.650. Epub 2011 Mar 17.

PMID:
21424112
[PubMed - indexed for MEDLINE]
20.

A vision and strategy for the virtual physiological human in 2010 and beyond.

Hunter P, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Skår J, Tegner J, Randall Thomas S, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Philos Trans A Math Phys Eng Sci. 2010 Jun 13;368(1920):2595-614. doi: 10.1098/rsta.2010.0048.

PMID:
20439264
[PubMed - indexed for MEDLINE]
Free PMC Article

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