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Results: 1 to 20 of 78

1.

An integrative analysis reveals coordinated reprogramming of the epigenome and the transcriptome in human skeletal muscle after training.

Lindholm ME, Marabita F, Gomez-Cabrero D, Rundqvist H, Ekström TJ, Tegnér J, Sundberg CJ.

Epigenetics. 2014 Dec 2;9(12):1557-69. doi: 10.4161/15592294.2014.982445.

PMID:
25484259
[PubMed - in process]
2.

Chronic Obstructive Pulmonary Disease heterogeneity: challenges for health risk assessment, stratification and management.

Roca J, Vargas C, Cano I, Selivanov V, Barreiro E, Maier D, Falciani F, Wagner P, Cascante M, Garcia-Aymerich J, Kalko S, De Mas I, Tegnér J, Escarrabill J, Agustí A, Gomez-Cabrero D; Synergy-COPD consortium.

J Transl Med. 2014 Nov 28;12 Suppl 2:S3. doi: 10.1186/1479-5876-12-S2-S3. Epub 2014 Nov 28.

PMID:
25472887
[PubMed - in process]
Free PMC Article
3.

Synergy-COPD: a systems approach for understanding and managing chronic diseases.

Gomez-Cabrero D, Lluch-Ariet M, Tegnér J, Cascante M, Miralles F, Roca J; Synergy-COPD consortium.

J Transl Med. 2014 Nov 28;12 Suppl 2:S2. doi: 10.1186/1479-5876-12-S2-S2. Epub 2014 Nov 28.

PMID:
25472826
[PubMed - in process]
Free PMC Article
4.

Predictive medicine: outcomes, challenges and opportunities in the Synergy-COPD project.

Miralles F, Gomez-Cabrero D, Lluch-Ariet M, Tegnér J, Cascante M, Roca J; Synergy-COPD consortium.

J Transl Med. 2014 Nov 28;12 Suppl 2:S12. doi: 10.1186/1479-5876-12-S2-S12. Epub 2014 Nov 28.

PMID:
25472742
[PubMed - in process]
Free PMC Article
5.

Biomedical research in a Digital Health Framework.

Cano I, Lluch-Ariet M, Gomez-Cabrero D, Maier D, Kalko S, Cascante M, Tegnér J, Miralles F, Herrera D, Roca J; Synergy-COPD consortium.

J Transl Med. 2014 Nov 28;12 Suppl 2:S10. doi: 10.1186/1479-5876-12-S2-S10. Epub 2014 Nov 28.

PMID:
25472554
[PubMed - in process]
Free PMC Article
6.

Systems Medicine: from molecular features and models to the clinic in COPD.

Gomez-Cabrero D, Menche J, Cano I, Abugessaisa I, Huertas-Migueláñez M, Tenyi A, Marin de Mas I, Kiani NA, Marabita F, Falciani F, Burrowes K, Maier D, Wagner P, Selivanov V, Cascante M, Roca J, Barabási AL, Tegnér J.

J Transl Med. 2014 Nov 28;12 Suppl 2:S4. doi: 10.1186/1479-5876-12-S2-S4. Epub 2014 Nov 28.

PMID:
25471042
[PubMed - in process]
Free PMC Article
7.

Oxygen pathway modeling estimates high reactive oxygen species production above the highest permanent human habitation.

Cano I, Selivanov V, Gomez-Cabrero D, Tegnér J, Roca J, Wagner PD, Cascante M.

PLoS One. 2014 Nov 6;9(11):e111068. doi: 10.1371/journal.pone.0111068. eCollection 2014.

PMID:
25375931
[PubMed - in process]
Free PMC Article
8.

Accelerating translational research by clinically driven development of an informatics platform--a case study.

Abugessaisa I, Saevarsdottir S, Tsipras G, Lindblad S, Sandin C, Nikamo P, Ståhle M, Malmström V, Klareskog L, Tegnér J.

PLoS One. 2014 Sep 9;9(9):e104382. doi: 10.1371/journal.pone.0104382. eCollection 2014.

PMID:
25203647
[PubMed - in process]
Free PMC Article
9.

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

Snir O, Gomez-Cabrero D, Montes A, Perez-Pampin E, Gómez-Reino JJ, Seddighzadeh M, Klich KU, Israelsson L, Ding B, Catrina AI, Holmdahl R, Alfredsson L, Klareskog L, Tegnér J, Gonzalez A, Malmström V, Padyukov L.

Arthritis Res Ther. 2014 Aug 20;16(4):414. doi: 10.1186/s13075-014-0414-3.

PMID:
25138370
[PubMed - in process]
Free PMC Article
10.

Signaling networks in MS: A systems-based approach to developing new pharmacological therapies.

Kotelnikova E, Bernardo-Faura M, Silberberg G, Kiani NA, Messinis D, Melas IN, Artigas L, Schwartz E, Mazo I, Masso M, Alexopoulos LG, Mas JM, Olsson T, Tegner J, Martin R, Zamora A, Paul F, Saez-Rodriguez J, Villoslada P.

Mult Scler. 2015 Feb;21(2):138-46. doi: 10.1177/1352458514543339. Epub 2014 Aug 11.

PMID:
25112814
[PubMed - in process]
11.

STATegra EMS: an Experiment Management System for complex next-generation omics experiments.

Hernández-de-Diego R, Boix-Chova N, Gómez-Cabrero D, Tegner J, Abugessaisa I, Conesa A.

BMC Syst Biol. 2014;8 Suppl 2:S9. doi: 10.1186/1752-0509-8-S2-S9. Epub 2014 Mar 13.

PMID:
25033091
[PubMed - in process]
Free PMC Article
12.

Data integration in the era of omics: current and future challenges.

Gomez-Cabrero D, Abugessaisa I, Maier D, Teschendorff A, Merkenschlager M, Gisel A, Ballestar E, Bongcam-Rudloff E, Conesa A, Tegnér J.

BMC Syst Biol. 2014;8 Suppl 2:I1. doi: 10.1186/1752-0509-8-S2-I1. Epub 2014 Mar 13.

PMID:
25032990
[PubMed - in process]
Free PMC Article
13.

A vision and strategy for the virtual physiological human: 2012 update.

Hunter P, Chapman T, Coveney PV, de Bono B, Diaz V, Fenner J, Frangi AF, Harris P, Hose R, Kohl P, Lawford P, McCormack K, Mendes M, Omholt S, Quarteroni A, Shublaq N, Skår J, Stroetmann K, Tegner J, Thomas SR, Tollis I, Tsamardinos I, van Beek JH, Viceconti M.

Interface Focus. 2013 Apr 6;3(2):20130004. doi: 10.1098/rsfs.2013.0004.

PMID:
24427536
[PubMed]
Free PMC Article
14.

Importance of mitochondrial P(O2) in maximal O2 transport and utilization: a theoretical analysis.

Cano I, Mickael M, Gomez-Cabrero D, Tegnér J, Roca J, Wagner PD.

Respir Physiol Neurobiol. 2013 Dec 1;189(3):477-83. doi: 10.1016/j.resp.2013.08.020. Epub 2013 Sep 5.

PMID:
24012990
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Implementation of the CDC translational informatics platform--from genetic variants to the national Swedish Rheumatology Quality Register.

Abugessaisa I, Gomez-Cabrero D, Snir O, Lindblad S, Klareskog L, Malmström V, Tegnér J.

J Transl Med. 2013 Apr 2;11:85. doi: 10.1186/1479-5876-11-85.

PMID:
23548156
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform.

Marabita F, Almgren M, Lindholm ME, Ruhrmann S, Fagerström-Billai F, Jagodic M, Sundberg CJ, Ekström TJ, Teschendorff AE, Tegnér J, Gomez-Cabrero D.

Epigenetics. 2013 Mar;8(3):333-46. doi: 10.4161/epi.24008. Epub 2013 Feb 19.

PMID:
23422812
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pediatric systems medicine: evaluating needs and opportunities using congenital heart block as a case study.

Tegnér J, Abugessaisa I.

Pediatr Res. 2013 Apr;73(4 Pt 2):508-13. doi: 10.1038/pr.2013.19. Epub 2013 Jan 31. Review.

PMID:
23370412
[PubMed - indexed for MEDLINE]
18.

Identification of novel markers in rheumatoid arthritis through integrated analysis of DNA methylation and microRNA expression.

de la Rica L, Urquiza JM, Gómez-Cabrero D, Islam AB, López-Bigas N, Tegnér J, Toes RE, Ballestar E.

J Autoimmun. 2013 Mar;41:6-16. doi: 10.1016/j.jaut.2012.12.005. Epub 2013 Jan 8.

PMID:
23306098
[PubMed - indexed for MEDLINE]
19.

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data.

Teschendorff AE, Marabita F, Lechner M, Bartlett T, Tegner J, Gomez-Cabrero D, Beck S.

Bioinformatics. 2013 Jan 15;29(2):189-96. doi: 10.1093/bioinformatics/bts680. Epub 2012 Nov 21.

PMID:
23175756
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Workflow for generating competing hypothesis from models with parameter uncertainty.

Gomez-Cabrero D, Compte A, Tegner J.

Interface Focus. 2011 Jun 6;1(3):438-49. doi: 10.1098/rsfs.2011.0015. Epub 2011 Mar 30.

PMID:
22670212
[PubMed]
Free PMC Article
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