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Results: 1 to 20 of 140


The limited ability of posaconazole to cure both acute and chronic Trypanosoma cruzi infections revealed by highly sensitive in vivo imaging.

Fortes Francisco A, Lewis MD, Jayawardhana S, Taylor MC, Chatelain E, Kelly JM.

Antimicrob Agents Chemother. 2015 May 26. pii: AAC.00520-15. [Epub ahead of print]


The Trypanosoma cruzi vitamin C dependent peroxidase confers protection against oxidative stress but is not a determinant of virulence.

Taylor MC, Lewis MD, Fortes Francisco A, Wilkinson SR, Kelly JM.

PLoS Negl Trop Dis. 2015 Apr 13;9(4):e0003707. doi: 10.1371/journal.pntd.0003707. eCollection 2015 Apr.


Metabolic engineering of medium-chain fatty acid biosynthesis in Nicotiana benthamiana plant leaf lipids.

Reynolds KB, Taylor MC, Zhou XR, Vanhercke T, Wood CC, Blanchard CL, Singh SP, Petrie JR.

Front Plant Sci. 2015 Mar 24;6:164. doi: 10.3389/fpls.2015.00164. eCollection 2015.


Systematic investigation of drip stains on apparel fabrics: The effects of prior-laundering, fibre content and fabric structure on final stain appearance.

de Castro TC, Taylor MC, Kieser JA, Carr DJ, Duncan W.

Forensic Sci Int. 2015 May;250:98-109. doi: 10.1016/j.forsciint.2015.03.004. Epub 2015 Mar 17.


Experimental and computational investigation of the trajectories of blood drops ejected from the nose.

Geoghegan PH, Spence CJ, Wilhelm J, Kabaliuk N, Taylor MC, Jermy MC.

Int J Legal Med. 2015 Mar 15. [Epub ahead of print]


Synthesis, biological profiling and mechanistic studies of 4-aminoquinoline-based heterodimeric compounds with dual trypanocidal-antiplasmodial activity.

Sola I, Castellà S, Viayna E, Galdeano C, Taylor MC, Gbedema SY, Pérez B, Clos MV, Jones DC, Fairlamb AH, Wright CW, Kelly JM, Muñoz-Torrero D.

Bioorg Med Chem. 2015 Jan 24. pii: S0968-0896(15)00047-4. doi: 10.1016/j.bmc.2015.01.031. [Epub ahead of print]


Atmospheric hydrogen scavenging: from enzymes to ecosystems.

Greening C, Constant P, Hards K, Morales S, Oakeshott JG, Russell RJ, Taylor MC, Berney M, Conrad R, Cook GM.

Appl Environ Microbiol. 2014 Dec 12. pii: AEM.03364-14. [Epub ahead of print]


Visualization of the air ejected from the temporary cavity in brain and tissue simulants during gunshot wounding.

Lazarjan MS, Geoghegan PH, Taylor MC, Jermy MC.

Forensic Sci Int. 2015 Jan;246:104-9. doi: 10.1016/j.forsciint.2014.11.005. Epub 2014 Nov 15.


Synthesis and antiprotozoal activity of oligomethylene- and p-phenylene-bis(methylene)-linked bis(+)-huprines.

Sola I, Artigas A, Taylor MC, Gbedema SY, Pérez B, Clos MV, Wright CW, Kelly JM, Muñoz-Torrero D.

Bioorg Med Chem Lett. 2014 Dec 1;24(23):5435-8.


TrypanoCyc: a community-led biochemical pathways database for Trypanosoma brucei.

Shameer S, Logan-Klumpler FJ, Vinson F, Cottret L, Merlet B, Achcar F, Boshart M, Berriman M, Breitling R, Bringaud F, Bütikofer P, Cattanach AM, Bannerman-Chukualim B, Creek DJ, Crouch K, de Koning HP, Denise H, Ebikeme C, Fairlamb AH, Ferguson MA, Ginger ML, Hertz-Fowler C, Kerkhoven EJ, Mäser P, Michels PA, Nayak A, Nes DW, Nolan DP, Olsen C, Silva-Franco F, Smith TK, Taylor MC, Tielens AG, Urbaniak MD, van Hellemond JJ, Vincent IM, Wilkinson SR, Wyllie S, Opperdoes FR, Barrett MP, Jourdan F.

Nucleic Acids Res. 2015 Jan;43(Database issue):D637-44. doi: 10.1093/nar/gku944. Epub 2014 Oct 9.


A new experimental model for assessing drug efficacy against Trypanosoma cruzi infection based on highly sensitive in vivo imaging.

Lewis MD, Francisco AF, Taylor MC, Kelly JM.

J Biomol Screen. 2015 Jan;20(1):36-43. doi: 10.1177/1087057114552623. Epub 2014 Oct 8.


Bioluminescence imaging of chronic Trypanosoma cruzi infections reveals tissue-specific parasite dynamics and heart disease in the absence of locally persistent infection.

Lewis MD, Fortes Francisco A, Taylor MC, Burrell-Saward H, McLatchie AP, Miles MA, Kelly JM.

Cell Microbiol. 2014 Sep;16(9):1285-300. doi: 10.1111/cmi.12297. Epub 2014 May 1.


Optimizing bioluminescence imaging to study protozoan parasite infections.

Taylor MC, Kelly JM.

Trends Parasitol. 2014 Apr;30(4):161-2. doi: 10.1016/ Epub 2014 Jan 28.


Benznidazole-resistance in Trypanosoma cruzi: evidence that distinct mechanisms can act in concert.

Campos MC, Leon LL, Taylor MC, Kelly JM.

Mol Biochem Parasitol. 2014 Jan;193(1):17-9. doi: 10.1016/j.molbiopara.2014.01.002. Epub 2014 Jan 23.


Highly sensitive in vivo imaging of Trypanosoma brucei expressing "red-shifted" luciferase.

McLatchie AP, Burrell-Saward H, Myburgh E, Lewis MD, Ward TH, Mottram JC, Croft SL, Kelly JM, Taylor MC.

PLoS Negl Trop Dis. 2013 Nov 21;7(11):e2571. doi: 10.1371/journal.pntd.0002571. eCollection 2013 Nov.


The impact of local black residents' socioeconomic status on white residents' racial views.

Taylor MC, Reyes AM.

Soc Sci Res. 2014 Jan;43:16-29. doi: 10.1016/j.ssresearch.2013.08.001. Epub 2013 Aug 17.


In vivo imaging of trypanosome-brain interactions and development of a rapid screening test for drugs against CNS stage trypanosomiasis.

Myburgh E, Coles JA, Ritchie R, Kennedy PG, McLatchie AP, Rodgers J, Taylor MC, Barrett MP, Brewer JM, Mottram JC.

PLoS Negl Trop Dis. 2013 Aug 22;7(8):e2384. doi: 10.1371/journal.pntd.0002384. eCollection 2013.


An E/Z conformational behaviour study on the trypanocidal action of lipophilic spiro carbocyclic 2,6-diketopiperazine-1-acetohydroxamic acids.

Tsatsaroni A, Zoidis G, Zoumpoulakis P, Tsotinis A, Taylor MC, Kelly JM, Fytas G.

Tetrahedron Lett. 2013 Jun 19;54(25):3238-3240.


Evidence that transport of iron from the lysosome to the cytosol in African trypanosomes is mediated by a mucolipin orthologue.

Taylor MC, McLatchie AP, Kelly JM.

Mol Microbiol. 2013 Aug;89(3):420-32. doi: 10.1111/mmi.12285. Epub 2013 Jun 27.

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