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BMC Infect Dis. 2012 Nov 14;12:300. doi: 10.1186/1471-2334-12-300.

Aedes albopictus in Lebanon, a potential risk of arboviruses outbreak.

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  • 1Institut Pasteur, Department of Virology, Arboviruses and Insect Vectors, 25-28 rue du Dr Roux, 75724 Paris cedex 15, France.

Abstract

BACKGROUND:

The mosquito Aedes albopictus is undergoing a worldwide expansion with potential consequences on transmission of various arboviruses. This species has been first detected in Lebanon in 2003.

METHODS:

We performed a phylogenetic study of Lebanese specimens and assessed their host preference by detecting human, cat, dog and chicken immunoglobulins in mosquito blood-meals. Their capacity to transmit arboviruses was investigated by providing infectious blood-meals using an artificial feeding system followed by detection of viral particles in mosquito saliva.

RESULTS:

Our results suggest that Lebanese strains are part of the recent wave of Ae. albopictus expansion and are related to some European, African and North American strains. They exhibited a host preference towards humans and an important capacity to transmit arboviruses. Indeed, we showed that Ae. albopictus was able to transmit chikungunya (CHIKV), dengue (DENV) and West-Nile (WNV) viruses. At day 10 after an infectious blood-meal at a titer of 108 MID50/ml, 30% of mosquitoes delivered an average of 515 ± 781 viral particles of CHIKV in saliva collected using a forced salivation technique and 55% with an average of 245 ± 304 viral particles when infected with WNV. Whereas DENV was not found in saliva at day 10 post-infection (pi), an average of 174 ± 455 viral particles was detected in 38.1% of mosquitoes tested at day 21 after an infectious blood-meal at a higher titer of 109 MID50/ml.

CONCLUSION:

These observations suggest that Ae. albopictus around Beirut is a potential vector of the three tested arboviruses.

PMID:
23151056
[PubMed - indexed for MEDLINE]
PMCID:
PMC3519687
Free PMC Article
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