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Results: 1 to 20 of 84

1.

Vitamin D Modulates Expression of the Airway Smooth Muscle Transcriptome in Fatal Asthma.

Himes BE, Koziol-White C, Johnson M, Nikolos C, Jester W, Klanderman B, Litonjua AA, Tantisira KG, Truskowski K, MacDonald K, Panettieri RA Jr, Weiss ST.

PLoS One. 2015 Jul 24;10(7):e0134057. doi: 10.1371/journal.pone.0134057. eCollection 2015.

2.

Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese.

Strunk RC, Colvin R, Bacharier LB, Fuhlbrigge A, Forno E, Arbelaez AM, Tantisira KG; Childhood Asthma Management Program Research Group.

J Allergy Clin Immunol Pract. 2015 Jul 8. pii: S2213-2198(15)00254-8. doi: 10.1016/j.jaip.2015.05.009. [Epub ahead of print]

PMID:
26164807
3.

Asthma Pharmacogenomics: 2015 Update.

Davis JS, Weiss ST, Tantisira KG.

Curr Allergy Asthma Rep. 2015 Jul;15(7):544. doi: 10.1007/s11882-015-0544-y.

PMID:
26143396
4.

Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma.

Dahlin A, Litonjua A, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Tantisira KG.

PLoS One. 2015 Jun 17;10(6):e0129385. doi: 10.1371/journal.pone.0129385. eCollection 2015.

5.

CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies.

McGeachie MJ, Wu AC, Tse SM, Clemmer GL, Sordillo J, Himes BE, Lasky-Su J, Chase RP, Martinez FD, Weeke P, Shaffer CM, Xu H, Denny JC, Roden DM, Panettieri RA Jr, Raby BA, Weiss ST, Tantisira KG.

J Allergy Clin Immunol. 2015 Jun 12. pii: S0091-6749(15)00646-6. doi: 10.1016/j.jaci.2015.04.039. [Epub ahead of print]

PMID:
26073756
6.

Genome-wide association study of leukotriene modifier response in asthma.

Dahlin A, Litonjua A, Irvin CG, Peters SP, Lima JJ, Kubo M, Tamari M, Tantisira KG.

Pharmacogenomics J. 2015 Jun 2. doi: 10.1038/tpj.2015.34. [Epub ahead of print]

PMID:
26031901
7.

Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

Park HW, Ge B, Tse S, Grundberg E, Pastinen T, Kelly HW, Tantisira KG.

J Allergy Clin Immunol. 2015 May 26. pii: S0091-6749(15)00574-6. doi: 10.1016/j.jaci.2015.04.014. [Epub ahead of print]

PMID:
26025128
8.

Measuring the corticosteroid responsiveness endophenotype in asthmatic patients.

Clemmer GL, Wu AC, Rosner B, McGeachie MJ, Litonjua AA, Tantisira KG, Weiss ST.

J Allergy Clin Immunol. 2015 Aug;136(2):274-281.e8. doi: 10.1016/j.jaci.2015.03.029. Epub 2015 May 5.

PMID:
25951964
9.

ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.

Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard EG, Palmer CN, Maitland-van der Zee AH.

Clin Exp Allergy. 2015 Jun;45(6):1051-9. doi: 10.1111/cea.12492.

PMID:
25616159
10.

Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma.

Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R.

Pharmacogenomics J. 2015 Jan 20. doi: 10.1038/tpj.2014.83. [Epub ahead of print]

PMID:
25601762
11.

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.

Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL.

Hum Mol Genet. 2015 Jun 1;24(11):3005-20. doi: 10.1093/hmg/ddv001. Epub 2015 Jan 12.

PMID:
25586491
12.

Genome-wide association study of short-acting ╬▓2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.

Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG; SHARP Investigators.

Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. doi: 10.1164/rccm.201408-1426OC.

PMID:
25562107
13.

Genomic architecture of pharmacological efficacy and adverse events.

Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA.

Pharmacogenomics. 2014 Dec;15(16):2025-48. doi: 10.2217/pgs.14.144. Review.

PMID:
25521360
14.

Fetal lung and placental methylation is associated with in utero nicotine exposure.

Chhabra D, Sharma S, Kho AT, Gaedigk R, Vyhlidal CA, Leeder JS, Morrow J, Carey VJ, Weiss ST, Tantisira KG, DeMeo DL.

Epigenetics. 2014 Nov;9(11):1473-84. doi: 10.4161/15592294.2014.971593.

PMID:
25482056
15.

Pharmacogenomics in asthma therapy: where are we and where do we go?

Park HW, Tantisira KG, Weiss ST.

Annu Rev Pharmacol Toxicol. 2015;55:129-47. doi: 10.1146/annurev-pharmtox-010814-124543. Epub 2014 Sep 29.

PMID:
25292431
16.

Genome-wide interrogation of longitudinal FEV1 in children with asthma.

Wu K, Gamazon ER, Im HK, Geeleher P, White SR, Solway J, Clemmer GL, Weiss ST, Tantisira KG, Cox NJ, Ratain MJ, Huang RS.

Am J Respir Crit Care Med. 2014 Sep 15;190(6):619-27. doi: 10.1164/rccm.201403-0460OC.

PMID:
25221879
17.

Glucocorticoid genes and the developmental origins of asthma susceptibility and treatment response.

Sharma S, Kho AT, Chhabra D, Qiu W, Gaedigk R, Vyhlidal CA, Leeder JS, Barraza-Villarreal A, London SJ, Gilliland F, Raby BA, Weiss ST, Tantisira KG.

Am J Respir Cell Mol Biol. 2015 May;52(5):543-53. doi: 10.1165/rcmb.2014-0109OC.

PMID:
25192440
18.

RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells.

Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri RA Jr, Tantisira KG, Weiss ST, Lu Q.

PLoS One. 2014 Jun 13;9(6):e99625. doi: 10.1371/journal.pone.0099625. eCollection 2014.

19.

Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis.

Qiu W, Rogers AJ, Damask A, Raby BA, Klanderman BJ, Duan QL, Tyagi S, Niu S, Anderson C, Cahir-Mcfarland E, Mariani TJ, Carey V, Tantisira KG.

Hum Mol Genet. 2014 Sep 15;23(18):5017-24. doi: 10.1093/hmg/ddu191. Epub 2014 Apr 25.

PMID:
24770851
20.

The genomic origins of asthma.

Sharma S, Chhabra D, Kho AT, Hayden LP, Tantisira KG, Weiss ST.

Thorax. 2014 May;69(5):481-7. doi: 10.1136/thoraxjnl-2014-205166. Epub 2014 Mar 25. Review.

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