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Results: 1 to 20 of 76

1.

ST13 polymorphisms and their effect on exacerbations in steroid-treated asthmatic children and young adults.

Vijverberg SJ, Koster ES, Tavendale R, Leusink M, Koenderman L, Raaijmakers JA, Postma DS, Koppelman GH, Turner SW, Mukhopadhyay S, Tse SM, Tantisira KG, Hawcutt DB, Francis B, Pirmohamed M, Pino-Yanes M, Eng C, Burchard EG, Palmer CN, Maitland-van der Zee AH.

Clin Exp Allergy. 2015 Jan 23. doi: 10.1111/cea.12492. [Epub ahead of print]

PMID:
25616159
2.

Pharmacodynamic genome-wide association study identifies new responsive loci for glucocorticoid intervention in asthma.

Wang Y, Tong C, Wang Z, Wang Z, Mauger D, Tantisira KG, Israel E, Szefler SJ, Chinchilli VM, Boushey HA, Lazarus SC, Lemanske RF, Wu R.

Pharmacogenomics J. 2015 Jan 20. doi: 10.1038/tpj.2014.83. [Epub ahead of print]

PMID:
25601762
3.

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in Asthma.

Sharma A, Menche J, Huang CC, Ort T, Zhou X, Kitsak M, Sahni N, Thibault D, Voung L, Guo F, Ghiassian SD, Gulbahce N, Baribaud F, Tocker J, Dobrin R, Barnathan E, Liu H, Panettieri RA Jr, Tantisira KG, Qiu W, Raby BA, Silverman EK, Vidal M, Weiss ST, Barabási AL.

Hum Mol Genet. 2015 Jan 12. pii: ddv001. [Epub ahead of print]

PMID:
25586491
4.

Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.

Israel E, Lasky-Su J, Markezich A, Damask A, Szefler SJ, Schuemann B, Klanderman B, Sylvia J, Kazani S, Wu R, Martinez F, Boushey HA, Chinchilli VM, Mauger D, Weiss ST, Tantisira KG; SHARP Investigators.

Am J Respir Crit Care Med. 2015 Mar 1;191(5):530-7. doi: 10.1164/rccm.201408-1426OC.

PMID:
25562107
5.

Genomic architecture of pharmacological efficacy and adverse events.

Chhibber A, Kroetz DL, Tantisira KG, McGeachie M, Cheng C, Plenge R, Stahl E, Sadee W, Ritchie MD, Pendergrass SA.

Pharmacogenomics. 2014 Dec;15(16):2025-48. doi: 10.2217/pgs.14.144.

PMID:
25521360
6.

Fetal lung and placental methylation is associated with in utero nicotine exposure.

Chhabra D, Sharma S, Kho AT, Gaedigk R, Vyhlidal CA, Leeder JS, Morrow J, Carey VJ, Weiss ST, Tantisira KG, DeMeo DL.

Epigenetics. 2014;9(11):1473-84. doi: 10.4161/15592294.2014.971593.

PMID:
25482056
7.

Pharmacogenomics in asthma therapy: where are we and where do we go?

Park HW, Tantisira KG, Weiss ST.

Annu Rev Pharmacol Toxicol. 2015;55:129-47. doi: 10.1146/annurev-pharmtox-010814-124543. Epub 2014 Sep 29.

PMID:
25292431
8.

Genome-wide interrogation of longitudinal FEV1 in children with asthma.

Wu K, Gamazon ER, Im HK, Geeleher P, White SR, Solway J, Clemmer GL, Weiss ST, Tantisira KG, Cox NJ, Ratain MJ, Huang RS.

Am J Respir Crit Care Med. 2014 Sep 15;190(6):619-27. doi: 10.1164/rccm.201403-0460OC.

PMID:
25221879
9.

Glucocorticoid Genes and the Developmental Origins of Asthma Susceptibility and Treatment Response.

Sharma S, Kho AT, Chhabra D, Qiu W, Gaedigk R, Vyhlidal CA, Leeder JS, Barraza-Villarreal A, London SJ, Gilliland F, Raby BA, Weiss ST, Tantisira KG.

Am J Respir Cell Mol Biol. 2014 Sep 5. [Epub ahead of print]

PMID:
25192440
10.

RNA-Seq transcriptome profiling identifies CRISPLD2 as a glucocorticoid responsive gene that modulates cytokine function in airway smooth muscle cells.

Himes BE, Jiang X, Wagner P, Hu R, Wang Q, Klanderman B, Whitaker RM, Duan Q, Lasky-Su J, Nikolos C, Jester W, Johnson M, Panettieri RA Jr, Tantisira KG, Weiss ST, Lu Q.

PLoS One. 2014 Jun 13;9(6):e99625. doi: 10.1371/journal.pone.0099625. eCollection 2014.

11.

Pharmacogenomics: novel loci identification via integrating gene differential analysis and eQTL analysis.

Qiu W, Rogers AJ, Damask A, Raby BA, Klanderman BJ, Duan QL, Tyagi S, Niu S, Anderson C, Cahir-Mcfarland E, Mariani TJ, Carey V, Tantisira KG.

Hum Mol Genet. 2014 Sep 15;23(18):5017-24. doi: 10.1093/hmg/ddu191. Epub 2014 Apr 25.

PMID:
24770851
12.

The genomic origins of asthma.

Sharma S, Chhabra D, Kho AT, Hayden LP, Tantisira KG, Weiss ST.

Thorax. 2014 May;69(5):481-7. doi: 10.1136/thoraxjnl-2014-205166. Epub 2014 Mar 25. Review.

PMID:
24668408
13.

Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids.

Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG.

J Allergy Clin Immunol. 2014 Mar;133(3):664-9.e5. doi: 10.1016/j.jaci.2013.12.1042. Epub 2014 Jan 31.

14.

Vitamin D related genes in lung development and asthma pathogenesis.

Kho AT, Sharma S, Qiu W, Gaedigk R, Klanderman B, Niu S, Anderson C, Leeder JS, Weiss ST, Tantisira KG.

BMC Med Genomics. 2013 Nov 5;6:47. doi: 10.1186/1755-8794-6-47.

15.

ITGB5 and AGFG1 variants are associated with severity of airway responsiveness.

Himes BE, Qiu W, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Nieuwenhuis MA, Postma DS, Vonk JM, Rafaels N, Hansel NN, Barnes K, Raby B, Tantisira KG, Weiss ST.

BMC Med Genet. 2013 Aug 28;14:86. doi: 10.1186/1471-2350-14-86.

16.

Diagnostic accuracy of the bronchodilator response in children.

Tse SM, Gold DR, Sordillo JE, Hoffman EB, Gillman MW, Rifas-Shiman SL, Fuhlbrigge AL, Tantisira KG, Weiss ST, Litonjua AA.

J Allergy Clin Immunol. 2013 Sep;132(3):554-559.e5. doi: 10.1016/j.jaci.2013.03.031. Epub 2013 May 14.

17.

Polygenic heritability estimates in pharmacogenetics: focus on asthma and related phenotypes.

McGeachie MJ, Stahl EA, Himes BE, Pendergrass SA, Lima JJ, Irvin CG, Peters SP, Ritchie MD, Plenge RM, Tantisira KG.

Pharmacogenet Genomics. 2013 Jun;23(6):324-8. doi: 10.1097/FPC.0b013e3283607acf.

18.

A genome-wide association study of bronchodilator response in asthmatics.

Duan QL, Lasky-Su J, Himes BE, Qiu W, Litonjua AA, Damask A, Lazarus R, Klanderman B, Irvin CG, Peters SP, Hanrahan JP, Lima JJ, Martinez FD, Mauger D, Chinchilli VM, Soto-Quiros M, Avila L, Celedón JC, Lange C, Weiss ST, Tantisira KG.

Pharmacogenomics J. 2014 Feb;14(1):41-7. doi: 10.1038/tpj.2013.5. Epub 2013 Mar 19.

19.

Integration of mouse and human genome-wide association data identifies KCNIP4 as an asthma gene.

Himes BE, Sheppard K, Berndt A, Leme AS, Myers RA, Gignoux CR, Levin AM, Gauderman WJ, Yang JJ, Mathias RA, Romieu I, Torgerson DG, Roth LA, Huntsman S, Eng C, Klanderman B, Ziniti J, Senter-Sylvia J, Szefler SJ, Lemanske RF Jr, Zeiger RS, Strunk RC, Martinez FD, Boushey H, Chinchilli VM, Israel E, Mauger D, Koppelman GH, Postma DS, Nieuwenhuis MA, Vonk JM, Lima JJ, Irvin CG, Peters SP, Kubo M, Tamari M, Nakamura Y, Litonjua AA, Tantisira KG, Raby BA, Bleecker ER, Meyers DA, London SJ, Barnes KC, Gilliland FD, Williams LK, Burchard EG, Nicolae DL, Ober C, DeMeo DL, Silverman EK, Paigen B, Churchill G, Shapiro SD, Weiss ST.

PLoS One. 2013;8(2):e56179. doi: 10.1371/journal.pone.0056179. Epub 2013 Feb 14.

20.

Cotinine in human placenta predicts induction of gene expression in fetal tissues.

Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS.

Drug Metab Dispos. 2013 Feb;41(2):305-11. doi: 10.1124/dmd.112.049999. Epub 2012 Dec 3.

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