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Items: 1 to 20 of 234

1.

Choroidal Thickness Changes in Age-Related Macular Degeneration and Polypoidal Choroidal Vasculopathy: A 12-Month Prospective Study.

Ting DS, Ng WY, Ng SR, Tan SP, Yeo IY, Mathur R, Chan CM, Tan AC, Tan GS, Wong TY, Cheung CM.

Am J Ophthalmol. 2015 Dec 29. pii: S0002-9394(15)30029-5. doi: 10.1016/j.ajo.2015.12.024. [Epub ahead of print]

PMID:
26743619
2.

Early biliary decompression versus conservative treatment in acute biliary pancreatitis (APEC trial): study protocol for a randomized controlled trial.

Schepers NJ, Bakker OJ, Besselink MG, Bollen TL, Dijkgraaf MG, van Eijck CH, Fockens P, van Geenen EJ, van Grinsven J, Hallensleben ND, Hansen BE, van Santvoort HC, Timmer R, Anten MP, Bolwerk CJ, van Delft F, van Dullemen HM, Erkelens GW, van Hooft JE, Laheij R, van der Hulst RW, Jansen JM, Kubben FJ, Kuiken SD, Perk LE, de Ridder RJ, Rijk MC, Römkens TE, Schoon EJ, Schwartz MP, Spanier BW, Tan AC, Thijs WJ, Venneman NG, Vleggaar FP, van de Vrie W, Witteman BJ, Gooszen HG, Bruno MJ; Dutch Pancreatitis Study Group.

Trials. 2016 Jan 5;17(1):5. doi: 10.1186/s13063-015-1132-0.

3.

A pilot study of cetuximab and the hedgehog inhibitor IPI-926 in recurrent/metastatic head and neck squamous cell carcinoma.

Bowles DW, Keysar SB, Eagles JR, Wang G, Glogowska MJ, McDermott JD, Le PN, Gao D, Ray CE, Rochon PJ, Roop DR, Tan AC, Serracino HS, Jimeno A.

Oral Oncol. 2016 Feb;53:74-9. doi: 10.1016/j.oraloncology.2015.11.014. Epub 2015 Dec 15.

PMID:
26705064
4.

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

Towers CG, Guarnieri AL, Micalizzi DS, Harrell JC, Gillen AE, Kim J, Wang CA, Oliphant MU, Drasin DJ, Guney MA, Kabos P, Sartorius CA, Tan AC, Perou CM, Espinosa JM, Ford HL.

Nat Commun. 2015 Dec 21;6:10077. doi: 10.1038/ncomms10077.

5.

An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.

Ryall KA, Kim J, Klauck PJ, Shin J, Yoo M, Ionkina A, Pitts TM, Tentler JJ, Diamond JR, Eckhardt S, Heasley LE, Kang J, Tan AC.

BMC Genomics. 2015 Dec 9;16 Suppl 12:S2. doi: 10.1186/1471-2164-16-S12-S2. Epub 2015 Dec 9.

6.

Expanding the computational toolbox for interrogating cancer kinomes.

Tan AC, Ryall KA, Huang PH.

Pharmacogenomics. 2016 Jan;17(2):95-7. doi: 10.2217/pgs.15.154. Epub 2015 Dec 15. No abstract available.

7.

Exploring example models of cross-sector, sessional employment of pharmacists to improve medication management and pharmacy support in rural hospitals.

Tan AC, Emmerton LM, Hattingh L, La Caze A.

Rural Remote Health. 2015 Oct-Dec;15(4):3441. Epub 2015 Nov 26.

8.

A quantitative analysis of therapeutic cancer vaccines in phase 2 or phase 3 trial.

Tan AC, Goubier A, Kohrt HE.

J Immunother Cancer. 2015 Nov 17;3:48. doi: 10.1186/s40425-015-0093-x. eCollection 2015. Review.

9.

Aging-associated inflammation promotes selection for adaptive oncogenic events in B cell progenitors.

Henry CJ, Casás-Selves M, Kim J, Zaberezhnyy V, Aghili L, Daniel AE, Jimenez L, Azam T, McNamee EN, Clambey ET, Klawitter J, Serkova NJ, Tan AC, Dinarello CA, DeGregori J.

J Clin Invest. 2015 Dec;125(12):4666-80. doi: 10.1172/JCI83024. Epub 2015 Nov 9.

PMID:
26551682
10.

Author Response: Use of Clopidogrel and Poor Visual Outcome.

Jung JJ, Chae B, Tan AC, Patel SN, Freund KB.

Invest Ophthalmol Vis Sci. 2015 Nov;56(12):7052. doi: 10.1167/iovs.15-18289. No abstract available.

PMID:
26529039
11.

Inactivated Influenza Vaccine That Provides Rapid, Innate-Immune-System-Mediated Protection and Subsequent Long-Term Adaptive Immunity.

Chua BY, Wong CY, Mifsud EJ, Edenborough KM, Sekiya T, Tan AC, Mercuri F, Rockman S, Chen W, Turner SJ, Doherty PC, Kelso A, Brown LE, Jackson DC.

MBio. 2015 Oct 27;6(6):e01024-15. doi: 10.1128/mBio.01024-15.

12.

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts.

Lieu CH, Klauck PJ, Henthorn PK, Tentler JJ, Tan AC, Spreafico A, Selby HM, Britt BC, Bagby SM, Arcaroli JJ, Messersmith WA, Pitts TM, Eckhardt SG.

Oncotarget. 2015 Oct 27;6(33):34561-72. doi: 10.18632/oncotarget.5949.

13.

Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC.

Singleton KR, Hinz TK, Kleczko EK, Marek LA, Kwak J, Harp T, Kim J, Tan AC, Heasley LE.

Cancer Res. 2015 Oct 15;75(20):4398-406. doi: 10.1158/0008-5472.CAN-15-0509. Epub 2015 Sep 10.

PMID:
26359452
14.

Mapping the pulmonary environment of animals protected from virulent H1N1 influenza infection using the TLR-2 agonist Pam2Cys.

Mifsud EJ, Tan AC, Reading PC, Jackson DC.

Immunol Cell Biol. 2015 Aug 14. doi: 10.1038/icb.2015.81. [Epub ahead of print]

PMID:
26272554
15.

Identifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition data.

Ryall KA, Shin J, Yoo M, Hinz TK, Kim J, Kang J, Heasley LE, Tan AC.

Bioinformatics. 2015 Dec 1;31(23):3799-806. doi: 10.1093/bioinformatics/btv427. Epub 2015 Jul 23.

PMID:
26206305
16.

A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.

Arcaroli JJ, Tai WM, McWilliams R, Bagby S, Blatchford PJ, Varella-Garcia M, Purkey A, Quackenbush KS, Song EK, Pitts TM, Gao D, Lieu C, McManus M, Tan AC, Zheng X, Zhang Q, Ozeck M, Olson P, Jiang ZQ, Kopetz S, Jimeno A, Keysar S, Eckhardt G, Messersmith WA.

Int J Cancer. 2016 Jan 1;138(1):195-205. doi: 10.1002/ijc.29676. Epub 2015 Jul 22.

17.

iCOSSY: An Online Tool for Context-Specific Subnetwork Discovery from Gene Expression Data.

Saha A, Jeon M, Tan AC, Kang J.

PLoS One. 2015 Jul 6;10(7):e0131656. doi: 10.1371/journal.pone.0131656. eCollection 2015.

18.

Combined inhibition of MEK and Aurora A kinase in KRAS/PIK3CA double-mutant colorectal cancer models.

Davis SL, Robertson KM, Pitts TM, Tentler JJ, Bradshaw-Pierce EL, Klauck PJ, Bagby SM, Hyatt SL, Selby HM, Spreafico A, Ecsedy JA, Arcaroli JJ, Messersmith WA, Tan AC, Eckhardt SG.

Front Pharmacol. 2015 Jun 16;6:120. doi: 10.3389/fphar.2015.00120. eCollection 2015.

19.

Reducing the impact of influenza-associated secondary pneumococcal infections.

Mifsud EJ, Tan AC, Short KR, Brown LE, Chua BY, Jackson DC.

Immunol Cell Biol. 2016 Jan;94(1):101-8. doi: 10.1038/icb.2015.71. Epub 2015 Jul 21.

PMID:
26134269
20.

Mammary epithelial cell phagocytosis downstream of TGF-β3 is characterized by adherens junction reorganization.

Fornetti J, Flanders KC, Henson PM, Tan AC, Borges VF, Schedin P.

Cell Death Differ. 2016 Feb;23(2):185-96. doi: 10.1038/cdd.2015.82. Epub 2015 Jun 26.

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