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Superior protection elicited by live-attenuated vaccines in the murine model of paratuberculosis.

Ghosh P, Shippy DC, Talaat AM.

Vaccine. 2015 Nov 5. pii: S0264-410X(15)01572-8. doi: 10.1016/j.vaccine.2015.10.116. [Epub ahead of print]


Protection by novel vaccine candidates, Mycobacterium tuberculosis ΔmosR and ΔechA7, against challenge with a Mycobacterium tuberculosis Beijing strain.

Marcus SA, Steinberg H, Talaat AM.

Vaccine. 2015 Oct 13;33(42):5633-9. doi: 10.1016/j.vaccine.2015.08.084. Epub 2015 Sep 9.


Virtual Screening for UDP-Galactopyranose Mutase Ligands Identifies a New Class of Antimycobacterial Agents.

Kincaid VA, London N, Wangkanont K, Wesener DA, Marcus SA, Héroux A, Nedyalkova L, Talaat AM, Forest KT, Shoichet BK, Kiessling LL.

ACS Chem Biol. 2015 Oct 16;10(10):2209-18. doi: 10.1021/acschembio.5b00370. Epub 2015 Aug 17.


A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis Infection.

Franklin RK, Marcus SA, Talaat AM, KuKanich BK, Sullivan R, Krugner-Higby LA, Heath TD.

Drug Metab Dispos. 2015 Aug;43(8):1236-45. doi: 10.1124/dmd.115.063602. Epub 2015 Jun 1.


Ecology and genomic features of infection with Mycobacterium avium subspecies paratuberculosis in Egypt.

Amin AS, Hsu CY, Darwish SF, Ghosh P, AbdEl-Fatah EM, Behour TS, Talaat AM.

Microbiology. 2015 Apr;161(Pt 4):807-18. doi: 10.1099/mic.0.000051. Epub 2015 Feb 8.


Controlling Johne's disease: vaccination is the way forward.

Bannantine JP, Talaat AM.

Front Cell Infect Microbiol. 2015 Jan 21;5:2. doi: 10.3389/fcimb.2015.00002. eCollection 2015. No abstract available.


A rational framework for evaluating the next generation of vaccines against Mycobacterium avium subspecies paratuberculosis.

Bannantine JP, Hines ME 2nd, Bermudez LE, Talaat AM, Sreevatsan S, Stabel JR, Chang YF, Coussens PM, Barletta RG, Davis WC, Collins DM, Gröhn YT, Kapur V.

Front Cell Infect Microbiol. 2014 Sep 9;4:126. doi: 10.3389/fcimb.2014.00126. eCollection 2014. Review.


Predictive role of urinary neutrophil gelatinase-associated lipocalin in lupus nephritis.

Elewa EA, El Tokhy MA, Fathy SE, Talaat AM.

Lupus. 2015 Feb;24(2):138-46. doi: 10.1177/0961203314550225. Epub 2014 Sep 8.


Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model.

Chirakul S, Bartpho T, Wongsurawat T, Taweechaisupapong S, Karoonutaisiri N, Talaat AM, Wongratanacheewin S, Ernst RK, Sermswan RW.

PLoS One. 2014 Aug 11;9(8):e104313. doi: 10.1371/journal.pone.0104313. eCollection 2014.


Evaluation of eight live attenuated vaccine candidates for protection against challenge with virulent Mycobacterium avium subspecies paratuberculosis in mice.

Bannantine JP, Everman JL, Rose SJ, Babrak L, Katani R, Barletta RG, Talaat AM, Gröhn YT, Chang YF, Kapur V, Bermudez LE.

Front Cell Infect Microbiol. 2014 Jul 1;4:88. doi: 10.3389/fcimb.2014.00088. eCollection 2014.


Screening of Mycobacterium avium subsp. paratuberculosis mutants for attenuation in a bovine monocyte-derived macrophage model.

Lamont EA, Talaat AM, Coussens PM, Bannantine JP, Grohn YT, Katani R, Li LL, Kapur V, Sreevatsan S.

Front Cell Infect Microbiol. 2014 Jun 30;4:87. doi: 10.3389/fcimb.2014.00087. eCollection 2014.


Virulence and immunity orchestrated by the global gene regulator sigL in Mycobacterium avium subsp. paratuberculosis.

Ghosh P, Steinberg H, Talaat AM.

Infect Immun. 2014 Jul;82(7):3066-75. doi: 10.1128/IAI.00001-14. Epub 2014 May 5.


Evaluation of novel oral vaccine candidates and validation of a caprine model of Johne's disease.

Hines ME 2nd, Turnquist SE, Ilha MR, Rajeev S, Jones AL, Whittington L, Bannantine JP, Barletta RG, Gröhn YT, Katani R, Talaat AM, Li L, Kapur V.

Front Cell Infect Microbiol. 2014 Mar 4;4:26. doi: 10.3389/fcimb.2014.00026. eCollection 2014.


A murine oral model for Mycobacterium avium subsp. paratuberculosis infection and immunomodulation with Lactobacillus casei ATCC 334.

Cooney MA, Steele JL, Steinberg H, Talaat AM.

Front Cell Infect Microbiol. 2014 Feb 5;4:11. doi: 10.3389/fcimb.2014.00011. eCollection 2014.


Key role for the alternative sigma factor, SigH, in the intracellular life of Mycobacterium avium subsp. paratuberculosis during macrophage stress.

Ghosh P, Wu CW, Talaat AM.

Infect Immun. 2013 Jun;81(6):2242-57. doi: 10.1128/IAI.01273-12. Epub 2013 Apr 8.


Single-cell elemental analysis of bacteria: quantitative analysis of polyphosphates in Mycobacterium tuberculosis.

Ward SK, Heintz JA, Albrecht RM, Talaat AM.

Front Cell Infect Microbiol. 2012 May 24;2:63. doi: 10.3389/fcimb.2012.00063. eCollection 2012.


Genomic islands as a marker to differentiate between clinical and environmental Burkholderia pseudomallei.

Bartpho T, Wongsurawat T, Wongratanacheewin S, Talaat AM, Karoonuthaisiri N, Sermswan RW.

PLoS One. 2012;7(6):e37762. doi: 10.1371/journal.pone.0037762. Epub 2012 Jun 1.


Genome sequencing of ovine isolates of Mycobacterium avium subspecies paratuberculosis offers insights into host association.

Bannantine JP, Wu CW, Hsu C, Zhou S, Schwartz DC, Bayles DO, Paustian ML, Alt DP, Sreevatsan S, Kapur V, Talaat AM.

BMC Genomics. 2012 Mar 12;13:89. doi: 10.1186/1471-2164-13-89.


Genome-wide analysis of the emerging infection with Mycobacterium avium subspecies paratuberculosis in the Arabian camels (Camelus dromedarius).

Ghosh P, Hsu C, Alyamani EJ, Shehata MM, Al-Dubaib MA, Al-Naeem A, Hashad M, Mahmoud OM, Alharbi KB, Al-Busadah K, Al-Swailem AM, Talaat AM.

PLoS One. 2012;7(2):e31947. doi: 10.1371/journal.pone.0031947. Epub 2012 Feb 29.

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