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Rats undernourished in utero have altered Ca2+ signaling and reduced fertility in adulthood.

Muzi-Filho H, Souza AM, Bezerra CG, Boldrini LC, Takiya CM, Oliveira FL, Nesi RT, Valença SS, Silva AM, Zapata-Sudo G, Sudo RT, Einicker-Lamas M, Vieyra A, Lara LS, Cunha VM.

Physiol Rep. 2015 Oct;3(10). pii: e12587. doi: 10.14814/phy2.12587.


P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice.

Vieira FS, Nanini HF, Takiya CM, Coutinho-Silva R.

Mol Cell Endocrinol. 2015 Oct 23. pii: S0303-7207(15)30109-X. doi: 10.1016/j.mce.2015.10.008. [Epub ahead of print]


Adipose Tissue-Derived Mesenchymal Stromal Cells Protect Mice Infected with Trypanosoma cruzi from Cardiac Damage through Modulation of Anti-parasite Immunity.

Mello DB, Ramos IP, Mesquita FC, Brasil GV, Rocha NN, Takiya CM, Lima AP, Campos de Carvalho AC, Goldenberg RS, Carvalho AB.

PLoS Negl Trop Dis. 2015 Aug 6;9(8):e0003945. doi: 10.1371/journal.pntd.0003945. eCollection 2015 Aug.


The Effects of Dasatinib in Experimental Acute Respiratory Distress Syndrome Depend on Dose and Etiology.

Oliveira GP, Silva JD, Marques PS, Gonçalves-de-Albuquerque CF, Santos HL, Vascocellos AP, Takiya CM, Morales MM, Pelosi P, Mócsai A, de Castro-Faria-Neto HC, Rocco PR.

Cell Physiol Biochem. 2015;36(4):1644-58.


The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis.

Santana PT, Benjamim CF, Martinez CG, Kurtenbach E, Takiya CM, Coutinho-Silva R.

J Innate Immun. 2015;7(4):417-27. doi: 10.1159/000371388. Epub 2015 Feb 13.


Regulation of aryl hydrocarbon receptor interacting protein (AIP) protein expression by MiR-34a in sporadic somatotropinomas.

Dénes J, Kasuki L, Trivellin G, Colli LM, Takiya CM, Stiles CE, Barry S, de Castro M, Gadelha MR, Korbonits M.

PLoS One. 2015 Feb 6;10(2):e0117107. doi: 10.1371/journal.pone.0117107. eCollection 2015.


Laceration in rat gastrocnemius. Following-up muscle repairing by ultrasound biomicroscopy (in vivo), contractility test (ex vivo) and histopathology.

Ferreira Filho CM, Silva AM, Sudo RT, Takiya CM, Machado JC.

Acta Cir Bras. 2015 Jan;30(1):13-23. doi: 10.1590/S0102-86502015001000003.


Dopamine receptor subtype 2 expression profile in nonfunctioning pituitary adenomas and in vivo response to cabergoline therapy.

Vieira Neto L, Wildemberg LE, Moraes AB, Colli LM, Kasuki L, Marques NV, Gasparetto EL, de Castro M, Takiya CM, Gadelha MR.

Clin Endocrinol (Oxf). 2015 May;82(5):739-46. doi: 10.1111/cen.12684. Epub 2015 Jan 8.


Early withdrawal of calcineurin inhibitor from a sirolimus-based immunosuppression stabilizes fibrosis and the transforming growth factor-β signalling pathway in kidney transplant.

Rivelli RF, Gonçalves RT, Leite M Jr, Santos MA, Delgado AG, Cardoso LR, Takiya CM.

Nephrology (Carlton). 2015 Mar;20(3):168-76. doi: 10.1111/nep.12368.


P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.

Monção-Ribeiro LC, Faffe DS, Santana PT, Vieira FS, da Graça CL, Marques-da-Silva C, Machado MN, Caruso-Neves C, Zin WA, Borojevic R, Takiya CM, Coutinho-Silva R.

PLoS One. 2014 Oct 13;9(10):e110185. doi: 10.1371/journal.pone.0110185. eCollection 2014.


5-Lypoxygenase products are involved in renal tubulointerstitial injury induced by albumin overload in proximal tubules in mice.

Landgraf SS, Silva LS, Peruchetti DB, Sirtoli GM, Moraes-Santos F, Portella VG, Silva-Filho JL, Pinheiro CS, Abreu TP, Takiya CM, Benjamin CF, Pinheiro AA, Canetti C, Caruso-Neves C.

PLoS One. 2014 Oct 10;9(10):e107549. doi: 10.1371/journal.pone.0107549. eCollection 2014.


Infusion of bone marrow mononuclear cells reduces lung fibrosis but not inflammation in the late stages of murine silicosis.

Lopes-Pacheco M, Ventura TG, de Oliveira HD, Monção-Ribeiro LC, Gutfilen B, de Souza SA, Rocco PR, Borojevic R, Morales MM, Takiya CM.

PLoS One. 2014 Oct 9;9(10):e109982. doi: 10.1371/journal.pone.0109982. eCollection 2014.


The protective role of fucosylated chondroitin sulfate, a distinct glycosaminoglycan, in a murine model of streptozotocin-induced diabetic nephropathy.

Gomes CL, Leão CL, Venturotti C, Barreira AL, Guimarães G, Fonseca RJ, Fortunato RS, Mourão PA, Delgado AG, Takiya CM, Leite M Jr.

PLoS One. 2014 Sep 5;9(9):e106929. doi: 10.1371/journal.pone.0106929. eCollection 2014.


Apoptosis-inducing effects of Melissa officinalis L. essential oil in glioblastoma multiforme cells.

Queiroz RM, Takiya CM, Guimarães LP, Rocha Gda G, Alviano DS, Blank AF, Alviano CS, Gattass CR.

Cancer Invest. 2014 Jul;32(6):226-35. doi: 10.3109/07357907.2014.905587. Epub 2014 Apr 18.


Mice rescued from severe malaria are protected against renal injury during a second kidney insult.

Abreu TP, Silva LS, Takiya CM, Souza MC, Henriques MG, Pinheiro AA, Caruso-Neves C.

PLoS One. 2014 Apr 15;9(4):e93634. doi: 10.1371/journal.pone.0093634. eCollection 2014.


Mesenchymal stem cells do not prevent antibody responses against human α-L-iduronidase when used to treat mucopolysaccharidosis type I.

Martin PK, Stilhano RS, Samoto VY, Takiya CM, Peres GB, da Silva Michelacci YM, da Silva FH, Pereira VG, D'Almeida V, Marques FL, Otake AH, Chammas R, Han SW.

PLoS One. 2014 Mar 18;9(3):e92420. doi: 10.1371/journal.pone.0092420. eCollection 2014.


The reciprocal interactions between astrocytes and prostate cancer cells represent an early event associated with brain metastasis.

de Oliveira Barros EG, Palumbo A Jr, Mello PL, de Mattos RM, da Silva JH, Pontes B, Viana NB, do Amaral RF, Lima FR, da Costa NM, Palmero CY, Miranda-Alves L, Takiya CM, Nasciutti LE.

Clin Exp Metastasis. 2014 Feb 1. [Epub ahead of print]


Intravenous glutamine administration reduces lung and distal organ injury in malnourished rats with sepsis.

de Oliveira GP, Silva JD, de Araújo CC, Prota LF, Abreu SC, Madeira C, Morales MM, Takiya CM, Diaz BL, Capelozzi VL, Panizzutti R, Pelosi P, Rocco PR.

Shock. 2014 Mar;41(3):222-32. doi: 10.1097/SHK.0000000000000102.


Impact of angiogenic therapy in the treatment of critical lower limb ischemia in an animal model.

Reis PE, de Carvalho LP, Yasumura E, da Silva FH, Garcia BC, Beutel A, Sacramento CB, Baptista-Silva JC, de Campos RR, Takiya CM, Borojevic R, Han SW.

Vasc Endovascular Surg. 2014 Apr;48(3):207-16. doi: 10.1177/1538574413518119. Epub 2014 Jan 6.


Repeated administration of bone marrow-derived cells prevents disease progression in experimental silicosis.

Lopes-Pacheco M, Xisto DG, Ornellas FM, Antunes MA, Abreu SC, Rocco PR, Takiya CM, Morales MM.

Cell Physiol Biochem. 2013;32(6):1681-94. doi: 10.1159/000356603. Epub 2013 Dec 13.

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