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Results: 1 to 20 of 275

1.

Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia.

Miyake M, Yamashiro K, Tabara Y, Suda K, Morooka S, Nakanishi H, Khor CC, Chen P, Qiao F, Nakata I, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Meguro A, Kusuhara S, Polasek O, Hayward C, Wright AF, Campbell H, Richardson AJ, Schache M, Takeuchi M, Mackey DA, Hewitt AW, Cuellar G, Shi Y, Huang L, Yang Z, Leung KH, Kao PY, Yap MK, Yip SP, Moriyama M, Ohno-Matsui K, Mizuki N, MacGregor S, Vitart V, Aung T, Saw SM, Tai ES, Wong TY, Cheng CY, Baird PN, Yamada R, Matsuda F; Nagahama Study Group, Yoshimura N.

Nat Commun. 2015 Mar 31;6:6689. doi: 10.1038/ncomms7689.

PMID:
25823570
2.

Corrigendum: New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Cheng CY, Yamashiro K, Jia Chen L, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC.

Nat Commun. 2015 Mar 30;6:6817. doi: 10.1038/ncomms7817. No abstract available.

PMID:
25817435
3.

Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in asian adults.

Lim CC, Teo BW, Tai ES, Lim SC, Chan CM, Sethi S, Wong TY, Sabanayagam C.

PLoS One. 2015 Mar 20;10(3):e0122009. doi: 10.1371/journal.pone.0122009. eCollection 2015.

4.

Aggregate Effects of Intraocular Pressure and Cup-to-Disc Ratio Genetic Variants on Glaucoma in a Multiethnic Asian Population.

Tham YC, Liao J, Vithana EN, Khor CC, Teo YY, Tai ES, Wong TY, Aung T, Cheng CY; International Glaucoma Genetics Consortium.

Ophthalmology. 2015 Mar 4. pii: S0161-6420(15)00097-4. doi: 10.1016/j.ophtha.2015.01.024. [Epub ahead of print]

PMID:
25745874
5.

Relationship between measured average glucose by continuous glucose monitor and HbA1c measured by three different routine laboratory methods.

Loh TP, Sethi SK, Wong MS, Tai ES, Kao SL.

Clin Biochem. 2015 Mar 1. pii: S0009-9120(15)00066-1. doi: 10.1016/j.clinbiochem.2015.02.012. [Epub ahead of print]

PMID:
25738920
6.

Factors associated with psychological distress, behavioral impact and health-related quality of life among patients with type 2 diabetes mellitus.

Co MA, Tan LS, Tai ES, Griva K, Amir M, Chong KJ, Lee YS, Lee J, Khoo EY, Wee HL.

J Diabetes Complications. 2015 Apr;29(3):378-83. doi: 10.1016/j.jdiacomp.2015.01.009. Epub 2015 Jan 24.

PMID:
25666950
7.

Retinal microvascular abnormalities and risk of renal failure in Asian populations.

Yip W, Sabanayagam C, Teo BW, Tay WT, Ikram MK, Tai ES, Chow KY, Wong TY, Cheung CY.

PLoS One. 2015 Feb 6;10(2):e0118076. doi: 10.1371/journal.pone.0118076. eCollection 2015.

8.

Meta-analysis of Genome-Wide Association Studies Identifies Novel Loci Associated With Optic Disc Morphology.

Springelkamp H, Mishra A, Hysi PG, Gharahkhani P, Höhn R, Khor CC, Cooke Bailey JN, Luo X, Ramdas WD, Vithana E, Koh V, Yazar S, Xu L, Forward H, Kearns LS, Amin N, Iglesias AI, Sim KS, van Leeuwen EM, Demirkan A, van der Lee S, Loon SC, Rivadeneira F, Nag A, Sanfilippo PG, Schillert A, de Jong PT, Oostra BA, Uitterlinden AG, Hofman A; NEIGHBORHOOD Consortium, Zhou T, Burdon KP, Spector TD, Lackner KJ, Saw SM, Vingerling JR, Teo YY, Pasquale LR, Wolfs RC, Lemij HG, Tai ES, Jonas JB, Cheng CY, Aung T, Jansonius NM, Klaver CC, Craig JE, Young TL, Haines JL, MacGregor S, Mackey DA, Pfeiffer N, Wong TY, Wiggs JL, Hewitt AW, van Duijn CM, Hammond CJ.

Genet Epidemiol. 2015 Mar;39(3):207-16. doi: 10.1002/gepi.21886. Epub 2015 Jan 28.

PMID:
25631615
9.

Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF, Raghavan S, Lipovich L, Hidalgo B, Fox K, Huffman JE, An P, Lu Y, Rasmussen-Torvik LJ, Grarup N, Ehm MG, Li L, Baldridge AS, Stančáková A, Abrol R, Besse C, Boland A, Bork-Jensen J, Fornage M, Freitag DF, Garcia ME, Guo X, Hara K, Isaacs A, Jakobsdottir J, Lange LA, Layton JC, Li M, Hua Zhao J, Meidtner K, Morrison AC, Nalls MA, Peters MJ, Sabater-Lleal M, Schurmann C, Silveira A, Smith AV, Southam L, Stoiber MH, Strawbridge RJ, Taylor KD, Varga TV, Allin KH, Amin N, Aponte JL, Aung T, Barbieri C, Bihlmeyer NA, Boehnke M, Bombieri C, Bowden DW, Burns SM, Chen Y, Chen YD, Cheng CY, Correa A, Czajkowski J, Dehghan A, Ehret GB, Eiriksdottir G, Escher SA, Farmaki AE, Frånberg M, Gambaro G, Giulianini F, Goddard WA 3rd, Goel A, Gottesman O, Grove ML, Gustafsson S, Hai Y, Hallmans G, Heo J, Hoffmann P, Ikram MK, Jensen RA, Jørgensen ME, Jørgensen T, Karaleftheri M, Khor CC, Kirkpatrick A, Kraja AT, Kuusisto J, Lange EM, Lee IT, Lee WJ, Leong A, Liao J, Liu C, Liu Y, Lindgren CM, Linneberg A, Malerba G, Mamakou V, Marouli E, Maruthur NM, Matchan A, McKean-Cowdin R, McLeod O, Metcalf GA, Mohlke KL, Muzny DM, Ntalla I, Palmer ND, Pasko D, Peter A, Rayner NW, Renström F, Rice K, Sala CF, Sennblad B, Serafetinidis I, Smith JA, Soranzo N, Speliotes EK, Stahl EA, Stirrups K, Tentolouris N, Thanopoulou A, Torres M, Traglia M, Tsafantakis E, Javad S, Yanek LR, Zengini E, Becker DM, Bis JC, Brown JB, Cupples LA, Hansen T, Ingelsson E, Karter AJ, Lorenzo C, Mathias RA, Norris JM, Peloso GM, Sheu WH, Toniolo D, Vaidya D, Varma R, Wagenknecht LE, Boeing H, Bottinger EP, Dedoussis G, Deloukas P, Ferrannini E, Franco OH, Franks PW, Gibbs RA, Gudnason V, Hamsten A, Harris TB, Hattersley AT, Hayward C, Hofman A, Jansson JH, Langenberg C, Launer LJ, Levy D, Oostra BA, O'Donnell CJ, O'Rahilly S, Padmanabhan S, Pankow JS, Polasek O, Province MA, Rich SS, Ridker PM, Rudan I, Schulze MB, Smith BH, Uitterlinden AG, Walker M, Watkins H, Wong TY, Zeggini E; EPIC-InterAct Consortium, Laakso M, Borecki IB, Chasman DI, Pedersen O, Psaty BM, Tai ES, van Duijn CM, Wareham NJ, Waterworth DM, Boerwinkle E, Kao WH, Florez JC, Loos RJ, Wilson JG, Frayling TM, Siscovick DS, Dupuis J, Rotter JI, Meigs JB, Scott RA, Goodarzi MO.

Nat Commun. 2015 Jan 29;6:5897. doi: 10.1038/ncomms6897.

10.

New loci and coding variants confer risk for age-related macular degeneration in East Asians.

Cheng CY, Yamashiro K, Chen LJ, Ahn J, Huang L, Huang L, Cheung CM, Miyake M, Cackett PD, Yeo IY, Laude A, Mathur R, Pang J, Sim KS, Koh AH, Chen P, Lee SY, Wong D, Chan CM, Loh BK, Sun Y, Davila S, Nakata I, Nakanishi H, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Matsuda F, Mori K, Yoneya S, Sakurada Y, Iijima H, Iida T, Honda S, Lai TY, Tam PO, Chen H, Tang S, Ding X, Wen F, Lu F, Zhang X, Shi Y, Zhao P, Zhao B, Sang J, Gong B, Dorajoo R, Yuan JM, Koh WP, van Dam RM, Friedlander Y, Lin Y, Hibberd ML, Foo JN, Wang N, Wong CH, Tan GS, Park SJ, Bhargava M, Gopal L, Naing T, Liao J, Ong PG, Mitchell P, Zhou P, Xie X, Liang J, Mei J, Jin X, Saw SM, Ozaki M, Mizoguchi T, Kurimoto Y, Woo SJ, Chung H, Yu HG, Shin JY, Park DH, Kim IT, Chang W, Sagong M, Lee SJ, Kim HW, Lee JE, Li Y, Liu J, Teo YY, Heng CK, Lim TH, Yang SK, Song K, Vithana EN, Aung T, Bei JX, Zeng YX, Tai ES, Li XX, Yang Z, Park KH, Pang CP, Yoshimura N, Wong TY, Khor CC.

Nat Commun. 2015 Jan 28;6:6063. doi: 10.1038/ncomms7063.

11.

Clinician scientists in public sector hospitals-why and how?

Tai ES.

Ann Acad Med Singapore. 2014 Dec;43(12):566-8. No abstract available.

12.

Anthropometrics indices of obesity, and all-cause and cardiovascular disease-related mortality, in an Asian cohort with type 2 diabetes mellitus.

Lim RB, Chen C, Naidoo N, Gay G, Tang WE, Seah D, Chen R, Tan NC, Lee J, Tai ES, Chia KS, Lim WY.

Diabetes Metab. 2015 Jan 6. pii: S1262-3636(14)00198-0. doi: 10.1016/j.diabet.2014.12.003. [Epub ahead of print]

PMID:
25575429
13.

Establishing the thematic framework for a diabetes-specific health-related quality of life item bank for use in an english-speaking asian population.

Koh O, Lee J, Tan ML, Tai ES, Foo CJ, Chong KJ, Goh SY, Bee YM, Thumboo J, Cheung YB, Singh A, Wee HL.

PLoS One. 2014 Dec 22;9(12):e115654. doi: 10.1371/journal.pone.0115654. eCollection 2014.

14.

Relationship of systemic endothelial function and peripheral arterial stiffness with diabetic retinopathy.

Lim LS, Ling LH, Cheung CM, Ong PG, Gong L, Tai ES, Mathur R, Wong D, Foulds W, Wong TY.

Br J Ophthalmol. 2014 Dec 8. pii: bjophthalmol-2014-306075. doi: 10.1136/bjophthalmol-2014-306075. [Epub ahead of print]

PMID:
25488949
15.

A novel splice-site mutation in ALS2 establishes the diagnosis of juvenile amyotrophic lateral sclerosis in a family with early onset anarthria and generalized dystonias.

Siddiqi S, Foo JN, Vu A, Azim S, Silver DL, Mansoor A, Tay SK, Abbasi S, Hashmi AH, Janjua J, Khalid S, Tai ES, Yeo GW, Khor CC.

PLoS One. 2014 Dec 4;9(12):e113258. doi: 10.1371/journal.pone.0113258. eCollection 2014.

16.

Forecasting the burden of type 2 diabetes in Singapore using a demographic epidemiological model of Singapore.

Phan TP, Alkema L, Tai ES, Tan KH, Yang Q, Lim WY, Teo YY, Cheng CY, Wang X, Wong TY, Chia KS, Cook AR.

BMJ Open Diabetes Res Care. 2014 Jun 11;2(1):e000012. doi: 10.1136/bmjdrc-2013-000012. eCollection 2014.

17.

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.

He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L.

Hum Mol Genet. 2015 Mar 15;24(6):1791-800. doi: 10.1093/hmg/ddu583. Epub 2014 Nov 26.

PMID:
25429064
18.

Associations between disease awareness and health-related quality of life in a multi-ethnic Asian population.

Venkataraman K, Khoo C, Wee HL, Tan CS, Ma S, Heng D, Lee J, Tai ES, Thumboo J.

PLoS One. 2014 Nov 26;9(11):e113802. doi: 10.1371/journal.pone.0113802. eCollection 2014.

19.

Diagnosis of diabetes mellitus using HbA1c in Asians: relationship between HbA1c and retinopathy in a multiethnic Asian population.

Sabanayagam C, Khoo EY, Lye WK, Ikram MK, Lamoureux EL, Cheng CY, Tan ML, Salim A, Lee J, Lim SC, Tavintharan S, Thai AC, Heng D, Ma S, Tai ES, Wong TY.

J Clin Endocrinol Metab. 2015 Feb;100(2):689-96. doi: 10.1210/jc.2014-2498. Epub 2014 Nov 6.

PMID:
25375980
20.

Allele frequencies of variants in ultra conserved elements identify selective pressure on transcription factor binding.

Silla T, Kepp K, Tai ES, Goh L, Davila S, Catela Ivkovic T, Calin GA, Voorhoeve PM.

PLoS One. 2014 Nov 4;9(11):e110692. doi: 10.1371/journal.pone.0110692. eCollection 2014.

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