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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1810 1
1816 2
1817 3
1852 2
1858 1
1866 1
1867 1
1872 1
1880 1
1882 1
1883 1
1884 1
1885 1
1886 2
1888 1
1890 1
1891 1
1892 1
1894 1
1895 1
1896 5
1897 3
1898 2
1899 2
1900 2
1901 3
1903 2
1905 1
1906 2
1908 1
1909 3
1912 1
1913 3
1914 3
1915 5
1916 1
1917 2
1918 8
1919 1
1920 4
1921 4
1922 6
1923 4
1924 4
1925 3
1926 5
1928 3
1929 5
1930 2
1931 4
1932 2
1933 4
1934 2
1935 3
1936 7
1937 7
1938 2
1939 10
1940 2
1941 3
1942 2
1943 6
1944 5
1945 125
1946 451
1947 387
1948 314
1949 282
1950 391
1951 490
1952 580
1953 612
1954 650
1955 619
1956 722
1957 840
1958 904
1959 917
1960 927
1961 1030
1962 1079
1963 1515
1964 2094
1965 1988
1966 2024
1967 2811
1968 3277
1969 3639
1970 3847
1971 4309
1972 4444
1973 4528
1974 4840
1975 5675
1976 5633
1977 5836
1978 6059
1979 6825
1980 7548
1981 7913
1982 8460
1983 9080
1984 10119
1985 10757
1986 11254
1987 11551
1988 12367
1989 13695
1990 14920
1991 15500
1992 16817
1993 17333
1994 18899
1995 19260
1996 20324
1997 20475
1998 22563
1999 23362
2000 26207
2001 28309
2002 29263
2003 30892
2004 32506
2005 34949
2006 38018
2007 39622
2008 41343
2009 42469
2010 44844
2011 47321
2012 50726
2013 52154
2014 52621
2015 53082
2016 52665
2017 52623
2018 53429
2019 54890
2020 59428
2021 61300
2022 58081
2023 54180
2024 22575

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1,364,616 results

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Page 1
Transporter-Mediated Drug Delivery.
Gyimesi G, Hediger MA. Gyimesi G, et al. Molecules. 2023 Jan 24;28(3):1151. doi: 10.3390/molecules28031151. Molecules. 2023. PMID: 36770817 Free PMC article. Review.
Transmembrane transport of small organic and inorganic molecules is one of the cornerstones of cellular metabolism. Among transmembrane transporters, solute carrier (SLC) proteins form the largest, albeit very diverse, superfamily with over 400 members. ...
Transmembrane transport of small organic and inorganic molecules is one of the cornerstones of cellular metabolism. Among transmembra …
Sucrose transporter in rice.
Wu Y, Fang W, Peng W, Jiang M, Chen G, Xiong F. Wu Y, et al. Plant Signal Behav. 2021 Nov 2;16(11):1952373. doi: 10.1080/15592324.2021.1952373. Epub 2021 Jul 16. Plant Signal Behav. 2021. PMID: 34269147 Free PMC article. Review.
Based on the literature, we highlight recent findings to summarize phloem loading by sucrose transport in rice. In rice, sucrose transporters, OsSUTs (sucrose transporters) and OsSWEETs (sugars are eventually exported transporters) import sucrose and e …
Based on the literature, we highlight recent findings to summarize phloem loading by sucrose transport in rice. In rice, sucrose t …
Transporter Specificity: A Tale of Loosened Elevator-Sliding.
Diallinas G. Diallinas G. Trends Biochem Sci. 2021 Sep;46(9):708-717. doi: 10.1016/j.tibs.2021.03.007. Epub 2021 Apr 23. Trends Biochem Sci. 2021. PMID: 33903007 Review.
Elevator-type transporters are a group of proteins translocating nutrients and metabolites across cell membranes. Despite structural and functional differences, elevator-type transporters use a common mechanism of substrate translocation via reversible moveme …
Elevator-type transporters are a group of proteins translocating nutrients and metabolites across cell membranes. Despite stru …
Transporter oligomerization: form and function.
Alguel Y, Cameron AD, Diallinas G, Byrne B. Alguel Y, et al. Biochem Soc Trans. 2016 Dec 15;44(6):1737-1744. doi: 10.1042/BST20160217. Biochem Soc Trans. 2016. PMID: 27913684 Free PMC article. Review.
Transporters are integral membrane proteins with central roles in the efficient movement of molecules across biological membranes. Many transporters exist as oligomers in the membrane. Depending on the individual transport protein, …
Transporters are integral membrane proteins with central roles in the efficient movement of molecules across biologi …
Transporter and its engineering for secondary metabolites.
Lv H, Li J, Wu Y, Garyali S, Wang Y. Lv H, et al. Appl Microbiol Biotechnol. 2016 Jul;100(14):6119-6130. doi: 10.1007/s00253-016-7605-6. Epub 2016 May 21. Appl Microbiol Biotechnol. 2016. PMID: 27209041 Review.
Secondary metabolites possess a lot of biological activities, and to achieve their functions, transmembrane transportation is crucial. ...Here, we have summarized the recent progresses for representative secondary metabolite transporters and also the strategi …
Secondary metabolites possess a lot of biological activities, and to achieve their functions, transmembrane transportation is …
Potentiating SLC transporter activity: Emerging drug discovery opportunities.
Rives ML, Javitch JA, Wickenden AD. Rives ML, et al. Biochem Pharmacol. 2017 Jul 1;135:1-11. doi: 10.1016/j.bcp.2017.02.010. Epub 2017 Feb 16. Biochem Pharmacol. 2017. PMID: 28214518 Review.
The two main transporter superfamilies are ATP-binding cassette (ABC) transporters that primarily function as efflux transporters, and the solute carrier (SLC) transporters. SLC transporters encompass 52 gene families with almost 400 different h …
The two main transporter superfamilies are ATP-binding cassette (ABC) transporters that primarily function as efflux transp …
Membrane transporter research in times of countless structures.
Seeger MA. Seeger MA. Biochim Biophys Acta Biomembr. 2018 Apr;1860(4):804-808. doi: 10.1016/j.bbamem.2017.08.009. Epub 2017 Aug 31. Biochim Biophys Acta Biomembr. 2018. PMID: 28867210 Free article. Review.
Structural biology has advanced our understanding of membrane proteins like no other scientific discipline in the past two decades and the number of high resolution membrane transporter structures solved by X-ray crystallography has increased exponenti …
Structural biology has advanced our understanding of membrane proteins like no other scientific discipline in the past two dec …
Xenobiotic transporter-adaptor network.
Kato Y. Kato Y. Drug Metab Pharmacokinet. 2007 Dec;22(6):401-8. doi: 10.2133/dmpk.22.401. Drug Metab Pharmacokinet. 2007. PMID: 18159127 Free article. Review.
So-called adaptor proteins that directly interact with the transporters include PDZ domain-containing proteins (PSD95, Dlg and ZO1). ...This review article summarizes recent evidence on the interactions of xenobiotic transporters with adaptor protei …
So-called adaptor proteins that directly interact with the transporters include PDZ domain-containing proteins (PSD95, …
The Important Role of Transporter Structures in Drug Disposition, Efficacy, and Toxicity.
Fu T, Zeng S, Zheng Q, Zhu F. Fu T, et al. Drug Metab Dispos. 2023 Oct;51(10):1316-1323. doi: 10.1124/dmd.123.001275. Epub 2023 Jun 9. Drug Metab Dispos. 2023. PMID: 37295948 Review.
SLC transporters are important drug targets involved in the uptake of a broad range of compounds across the membrane. ...P-glycoprotein and serotonin transporter were used as examples to reveal the pivotal role of structure in transport mechanisms, dru …
SLC transporters are important drug targets involved in the uptake of a broad range of compounds across the membrane. ...P-gly …
Transporter structure and mechanism.
DeFelice LJ. DeFelice LJ. Trends Neurosci. 2004 Jun;27(6):352-9. doi: 10.1016/j.tins.2004.04.007. Trends Neurosci. 2004. PMID: 15165740 Review.
This article describes the configuration and implied transport mechanism of the bacterial lactose transporter and compares its structure and function with those of other transporters and those of ion channels. This juxtaposition of transporters and cha …
This article describes the configuration and implied transport mechanism of the bacterial lactose transporter and compares its …
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