Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1961 1
1976 1
1986 1
1995 1
1997 1
1998 1
1999 2
2000 3
2001 2
2002 3
2003 3
2004 1
2005 6
2006 5
2007 7
2008 4
2009 4
2010 12
2011 17
2012 14
2013 10
2014 7
2015 11
2016 10
2017 15
2018 15
2019 15
2020 13
2021 23
2022 22
2023 24
2024 15

Text availability

Article attribute

Article type

Publication date

Search Results

235 results

Results by year

Filters applied: . Clear all
Page 1
Tiliroside Ameliorates Ulcerative Colitis by Restoring the M1/M2 Macrophage Balance via the HIF-1alpha/glycolysis Pathway.
Zhuang H, Lv Q, Zhong C, Cui Y, He L, Zhang C, Yu J. Zhuang H, et al. Front Immunol. 2021 Mar 31;12:649463. doi: 10.3389/fimmu.2021.649463. eCollection 2021. Front Immunol. 2021. PMID: 33868286 Free PMC article.
The macrophage depletion study further showed the protective effect of tiliroside was macrophage dependent in vivo. Mechanistically, our study demonstrated that tiliroside regulated cellular metabolism by inhibiting aerobic glycolysis in LPS and IFNgamma stimulated …
The macrophage depletion study further showed the protective effect of tiliroside was macrophage dependent in vivo. Mechanistically, …
Tiliroside targets TBK1 to induce ferroptosis and sensitize hepatocellular carcinoma to sorafenib.
Yang C, Lu T, Liu M, Yuan X, Li D, Zhang J, Zhou L, Xu M. Yang C, et al. Phytomedicine. 2023 Mar;111:154668. doi: 10.1016/j.phymed.2023.154668. Epub 2023 Jan 15. Phytomedicine. 2023. PMID: 36657316
Finally, subcutaneous xenograft and orthotopic xenograft tumors in nude mice were used to assess the effects of tiliroside in vivo. RESULTS: Tiliroside significantly enhanced the anti-HCC activity of sorafenib without any discernible side effects. Moreover, the comb …
Finally, subcutaneous xenograft and orthotopic xenograft tumors in nude mice were used to assess the effects of tiliroside in vivo. R …
Tiliroside Protects against Lipopolysaccharide-Induced Acute Kidney Injury via Intrarenal Renin-Angiotensin System in Mice.
Yi X, Xu C, Yang J, Zhong C, Yang H, Tang L, Song S, Yu J. Yi X, et al. Int J Mol Sci. 2023 Oct 25;24(21):15556. doi: 10.3390/ijms242115556. Int J Mol Sci. 2023. PMID: 37958538 Free PMC article.
Tiliroside, a natural flavonoid, has various biological activities and improves several inflammatory diseases in rodents. ...This study aimed to evaluate the potential renoprotective effect of Tiliroside on LPS-induced AKI in mice. Male C57BL/6 mice were intraperito …
Tiliroside, a natural flavonoid, has various biological activities and improves several inflammatory diseases in rodents. ...This stu …
Tiliroside attenuates acute kidney injury by inhibiting ferroptosis through the disruption of NRF2-KEAP1 interaction.
Cai F, Li D, Zhou K, Zhang W, Yang Y. Cai F, et al. Phytomedicine. 2024 Apr;126:155407. doi: 10.1016/j.phymed.2024.155407. Epub 2024 Feb 2. Phytomedicine. 2024. PMID: 38340577
METHODS: Possible tiliroside substrates were analyzed using molecular docking. Cisplatin- and ischemia-reperfusion injury (IRI)-induced AKI mouse models and HK2 cells model were constructed to evaluate the protective effects of tiliroside. ...In vitro, tiliroside …
METHODS: Possible tiliroside substrates were analyzed using molecular docking. Cisplatin- and ischemia-reperfusion injury (IRI)-induc …
Tiliroside induces ferroptosis to repress the development of triple-negative breast cancer cells.
Hu C, Zhao JF, Wang YM, Wu XL, Ye L. Hu C, et al. Tissue Cell. 2023 Aug;83:102116. doi: 10.1016/j.tice.2023.102116. Epub 2023 May 16. Tissue Cell. 2023. PMID: 37301139 Free article.
Ferroptosis is a newly found form of non-apoptotic regulated cell death that is essential for the advancement of cancer. Tiliroside (Til), an effective natural flavonoid glycoside of oriental paperbush flower, has been explored as a potential anticancer agent in a few canc …
Ferroptosis is a newly found form of non-apoptotic regulated cell death that is essential for the advancement of cancer. Tiliroside ( …
Tiliroside Combined with Anti-MUC1 Monoclonal Antibody as Promising Anti-Cancer Strategy in AGS Cancer Cells.
Radziejewska I, Supruniuk K, Jakimiuk K, Tomczyk M, Bielawska A, Galicka A. Radziejewska I, et al. Int J Mol Sci. 2023 Aug 22;24(17):13036. doi: 10.3390/ijms241713036. Int J Mol Sci. 2023. PMID: 37685842 Free PMC article.
Such altered glycans influence many cellular activities promoting cancer development. Tiliroside is a glycosidic dietary flavonoid with pharmacological properties, including anti-cancer. In this study, we aim to assess the effect of the combined action of anti-MUC1 and …
Such altered glycans influence many cellular activities promoting cancer development. Tiliroside is a glycosidic dietary flavonoid wi …
Tiliroside suppresses triple-negative breast cancer as a multifunctional CAXII inhibitor.
Han R, Yang H, Ling C, Lu L. Han R, et al. Cancer Cell Int. 2022 Nov 24;22(1):368. doi: 10.1186/s12935-022-02786-6. Cancer Cell Int. 2022. PMID: 36424626 Free PMC article.
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by poor prognosis, early recurrence, and the lack of durable chemotherapy responses and specific targeted treatments. In this preclinical study, we examines Tiliroside (TS, C(30)H( …
Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by poor prognosis, early recurrence, and the la …
Tiliroside as a CAXII inhibitor suppresses liver cancer development and modulates E2Fs/Caspase-3 axis.
Han R, Yang H, Lu L, Lin L. Han R, et al. Sci Rep. 2021 Apr 21;11(1):8626. doi: 10.1038/s41598-021-88133-7. Sci Rep. 2021. PMID: 33883691 Free PMC article.
Liver cancer is the fatal cause of cancer deaths worldwide due to its aggressiveness and lack of effective therapies. Tiliroside (C(30)H(26)O(13)) is an active compound extracted from herb plant Tribulus terrestris L., which has been used as alternative therapy in clinic p …
Liver cancer is the fatal cause of cancer deaths worldwide due to its aggressiveness and lack of effective therapies. Tiliroside (C(3 …
Tiliroside Attenuates NLRP3 Inflammasome Activation in Macrophages and Protects against Acute Lung Injury in Mice.
Zhong C, Yang J, Deng K, Lang X, Zhang J, Li M, Qiu L, Zhong G, Yu J. Zhong C, et al. Molecules. 2023 Nov 10;28(22):7527. doi: 10.3390/molecules28227527. Molecules. 2023. PMID: 38005247 Free PMC article.
Notably, tiliroside potently attenuated lipopolysaccharide (LPS)-induced acute lung injury in mice, which has been known to be NLRP3 inflammasome dependent. For the first time, this study identified that tiliroside is an NLRP3 inflammasome inhibitor and may represen …
Notably, tiliroside potently attenuated lipopolysaccharide (LPS)-induced acute lung injury in mice, which has been known to be NLRP3 …
trans-Tiliroside: A potent alpha-glucosidase inhibitor from the leaves of Elaeagnus angustifolia L.
Yuca H, Özbek H, Demirezer LÖ, Kasil HG, Güvenalp Z. Yuca H, et al. Phytochemistry. 2021 Aug;188:112795. doi: 10.1016/j.phytochem.2021.112795. Epub 2021 May 25. Phytochemistry. 2021. PMID: 34044297
Of the compounds extracted, kaempferol-3-O-(6"-trans-p-coumaroyl)-beta-D-glucopyranoside (trans-tiliroside), exhibited the highest alpha-glucosidase inhibitory activity with an IC(50) value of 2128 63 muM compared to the positive control, acarbose (IC(50) = 6561 207 muM). …
Of the compounds extracted, kaempferol-3-O-(6"-trans-p-coumaroyl)-beta-D-glucopyranoside (trans-tiliroside), exhibited the highest al …
235 results