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Items: 1 to 20 of 45

1.

r2VIM: A new variable selection method for random forests in genome-wide association studies.

Szymczak S, Holzinger E, Dasgupta A, Malley JD, Molloy AM, Mills JL, Brody LC, Stambolian D, Bailey-Wilson JE.

BioData Min. 2016 Feb 1;9:7. doi: 10.1186/s13040-016-0087-3. eCollection 2016.

2.

Sparse Modeling Reveals miRNA Signatures for Diagnostics of Inflammatory Bowel Disease.

Hübenthal M, Hemmrich-Stanisak G, Degenhardt F, Szymczak S, Du Z, Elsharawy A, Keller A, Schreiber S, Franke A.

PLoS One. 2015 Oct 14;10(10):e0140155. doi: 10.1371/journal.pone.0140155. eCollection 2015.

3.

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang W, Kelly TN, Saleheen D, Lehne B, Mateo Leach I, Drong AW, Abbott J, Wahl S, Tan ST, Scott WR, Campanella G, Chadeau-Hyam M, Afzal U, Ahluwalia TS, Bonder MJ, Chen P, Dehghan A, Edwards TL, Esko T, Go MJ, Harris SE, Hartiala J, Kasela S, Kasturiratne A, Khor CC, Kleber ME, Li H, Mok ZY, Nakatochi M, Sapari NS, Saxena R, Stewart AF, Stolk L, Tabara Y, Teh AL, Wu Y, Wu JY, Zhang Y, Aits I, Da Silva Couto Alves A, Das S, Dorajoo R, Hopewell JC, Kim YK, Koivula RW, Luan J, Lyytikäinen LP, Nguyen QN, Pereira MA, Postmus I, Raitakari OT, Bryan MS, Scott RA, Sorice R, Tragante V, Traglia M, White J, Yamamoto K, Zhang Y, Adair LS, Ahmed A, Akiyama K, Asif R, Aung T, Barroso I, Bjonnes A, Braun TR, Cai H, Chang LC, Chen CH, Cheng CY, Chong YS, Collins R, Courtney R, Davies G, Delgado G, Do LD, Doevendans PA, Gansevoort RT, Gao YT, Grammer TB, Grarup N, Grewal J, Gu D, Wander GS, Hartikainen AL, Hazen SL, He J, Heng CK, Hixson JE, Hofman A, Hsu C, Huang W, Husemoen LL, Hwang JY, Ichihara S, Igase M, Isono M, Justesen JM, Katsuya T, Kibriya MG, Kim YJ, Kishimoto M, Koh WP, Kohara K, Kumari M, Kwek K, Lee NR, Lee J, Liao J, Lieb W, Liewald DC, Matsubara T, Matsushita Y, Meitinger T, Mihailov E, Milani L, Mills R, Mononen N, Müller-Nurasyid M, Nabika T, Nakashima E, Ng HK, Nikus K, Nutile T, Ohkubo T, Ohnaka K, Parish S, Paternoster L, Peng H, Peters A, Pham ST, Pinidiyapathirage MJ, Rahman M, Rakugi H, Rolandsson O, Rozario MA, Ruggiero D, Sala CF, Sarju R, Shimokawa K, Snieder H, Sparsø T, Spiering W, Starr JM, Stott DJ, Stram DO, Sugiyama T, Szymczak S, Tang WH, Tong L, Trompet S, Turjanmaa V, Ueshima H, Uitterlinden AG, Umemura S, Vaarasmaki M, van Dam RM, van Gilst WH, van Veldhuisen DJ, Viikari JS, Waldenberger M, Wang Y, Wang A, Wilson R, Wong TY, Xiang YB, Yamaguchi S, Ye X, Young RD, Young TL, Yuan JM, Zhou X, Asselbergs FW, Ciullo M, Clarke R, Deloukas P, Franke A, Franks PW, Franks S, Friedlander Y, Gross MD, Guo Z, Hansen T, Jarvelin MR, Jørgensen T, Jukema JW, Kähönen M, Kajio H, Kivimaki M, Lee JY, Lehtimäki T, Linneberg A, Miki T, Pedersen O, Samani NJ, Sørensen TI, Takayanagi R, Toniolo D; BIOS-consortium; CARDIo GRAMplusCD; LifeLines Cohort Study; InterAct Consortium, Ahsan H, Allayee H, Chen YT, Danesh J, Deary IJ, Franco OH, Franke L, Heijman BT, Holbrook JD, Isaacs A, Kim BJ, Lin X, Liu J, März W, Metspalu A, Mohlke KL, Sanghera DK, Shu XO, van Meurs JB, Vithana E, Wickremasinghe AR, Wijmenga C, Wolffenbuttel BH, Yokota M, Zheng W, Zhu D, Vineis P, Kyrtopoulos SA, Kleinjans JC, McCarthy MI, Soong R, Gieger C, Scott J, Teo YY, He J, Elliott P, Tai ES, van der Harst P, Kooner JS, Chambers JC.

Nat Genet. 2015 Nov;47(11):1282-93. doi: 10.1038/ng.3405. Epub 2015 Sep 21.

4.

Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies.

Gemoll T, Epping F, Heinrich L, Fritzsche B, Roblick UJ, Szymczak S, Hartwig S, Depping R, Bruch HP, Thorns C, Lehr S, Paech A, Habermann JK.

Oncotarget. 2015 Jun 30;6(18):16517-26.

5.

Vy-PER: eliminating false positive detection of virus integration events in next generation sequencing data.

Forster M, Szymczak S, Ellinghaus D, Hemmrich G, Rühlemann M, Kraemer L, Mucha S, Wienbrandt L, Stanulla M; UFO Sequencing Consortium within I-BFM Study Group, Franke A.

Sci Rep. 2015 Jul 13;5:11534. doi: 10.1038/srep11534.

6.

A Hereditary Form of Small Intestinal Carcinoid Associated With a Germline Mutation in Inositol Polyphosphate Multikinase.

Sei Y, Zhao X, Forbes J, Szymczak S, Li Q, Trivedi A, Voellinger M, Joy G, Feng J, Whatley M, Jones MS, Harper UL, Marx SJ, Venkatesan AM, Chandrasekharappa SC, Raffeld M, Quezado MM, Louie A, Chen CC, Lim RM, Agarwala R, Schäffer AA, Hughes MS, Bailey-Wilson JE, Wank SA.

Gastroenterology. 2015 Jul;149(1):67-78. doi: 10.1053/j.gastro.2015.04.008. Epub 2015 Apr 9.

PMID:
25865046
7.

Variable selection method for the identification of epistatic models.

Holzinger ER, Szymczak S, Dasgupta A, Malley J, Li Q, Bailey-Wilson JE.

Pac Symp Biocomput. 2015:195-206.

8.

False-positive rates in two-point parametric linkage analysis.

Szymczak S, Simpson CL, Cropp CD, Bailey-Wilson JE.

BMC Proc. 2014 Jun 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S110. doi: 10.1186/1753-6561-8-S1-S110. eCollection 2014.

9.

Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity.

Reuther S, Szymczak S, Raabe A, Borgmann K, Ziegler A, Petersen C, Dikomey E, Hoeller U.

Strahlenther Onkol. 2015 Jan;191(1):59-66. doi: 10.1007/s00066-014-0741-y. Epub 2014 Aug 26.

PMID:
25156511
10.

Whole exome sequencing of distant relatives in multiplex families implicates rare variants in candidate genes for oral clefts.

Bureau A, Parker MM, Ruczinski I, Taub MA, Marazita ML, Murray JC, Mangold E, Noethen MM, Ludwig KU, Hetmanski JB, Bailey-Wilson JE, Cropp CD, Li Q, Szymczak S, Albacha-Hejazi H, Alqosayer K, Field LL, Wu-Chou YH, Doheny KF, Ling H, Scott AF, Beaty TH.

Genetics. 2014 Jul;197(3):1039-44. doi: 10.1534/genetics.114.165225. Epub 2014 May 2.

11.

Risk estimation using probability machines.

Dasgupta A, Szymczak S, Moore JH, Bailey-Wilson JE, Malley JD.

BioData Min. 2014 Mar 1;7(1):2. doi: 10.1186/1756-0381-7-2.

12.

Impact of NICU design on environmental noise.

Szymczak SE, Shellhaas RA.

J Neonatal Nurs. 2014 Apr 1;20(2):77-81.

13.

Chromosomal aneuploidy affects the global proteome equilibrium of colorectal cancer cells.

Gemoll T, Habermann JK, Becker S, Szymczak S, Upender MB, Bruch HP, Hellman U, Ried T, Auer G, Jörnvall H, Roblick UJ.

Anal Cell Pathol (Amst). 2013;36(5-6):149-61. doi: 10.3233/ACP-140088.

14.

Genomewide RNAi screen identifies protein kinase Cb and new members of mitogen-activated protein kinase pathway as regulators of melanoma cell growth and metastasis.

Schönherr M, Bhattacharya A, Kottek T, Szymczak S, Köberle M, Wickenhauser C, Siebolts U, Saalbach A, Koczan D, Magin TM, Simon JC, Kunz M.

Pigment Cell Melanoma Res. 2014 May;27(3):418-30. doi: 10.1111/pcmr.12216. Epub 2014 Jan 31.

PMID:
24406113
15.

Adaptive linear rank tests for eQTL studies.

Szymczak S, Scheinhardt MO, Zeller T, Wild PS, Blankenberg S, Ziegler A.

Stat Med. 2013 Feb 10;32(3):524-37. doi: 10.1002/sim.5593. Epub 2012 Aug 30.

16.

Association of single nucleotide polymorphisms in the genes ATM, GSTP1, SOD2, TGFB1, XPD and XRCC1 with risk of severe erythema after breast conserving radiotherapy.

Raabe A, Derda K, Reuther S, Szymczak S, Borgmann K, Hoeller U, Ziegler A, Petersen C, Dikomey E.

Radiat Oncol. 2012 Apr 26;7:65. doi: 10.1186/1748-717X-7-65.

17.

Deregulation of a distinct set of microRNAs is associated with transformation of gastritis into MALT lymphoma.

Thorns C, Kuba J, Bernard V, Senft A, Szymczak S, Feller AC, Bernd HW.

Virchows Arch. 2012 Apr;460(4):371-7. doi: 10.1007/s00428-012-1215-1. Epub 2012 Mar 7.

PMID:
22395483
18.

Integrating genome-wide genetic variations and monocyte expression data reveals trans-regulated gene modules in humans.

Rotival M, Zeller T, Wild PS, Maouche S, Szymczak S, Schillert A, Castagné R, Deiseroth A, Proust C, Brocheton J, Godefroy T, Perret C, Germain M, Eleftheriadis M, Sinning CR, Schnabel RB, Lubos E, Lackner KJ, Rossmann H, Münzel T, Rendon A; Cardiogenics Consortium, Erdmann J, Deloukas P, Hengstenberg C, Diemert P, Montalescot G, Ouwehand WH, Samani NJ, Schunkert H, Tregouet DA, Ziegler A, Goodall AH, Cambien F, Tiret L, Blankenberg S.

PLoS Genet. 2011 Dec;7(12):e1002367. doi: 10.1371/journal.pgen.1002367. Epub 2011 Dec 1.

19.

Influence of sex and genetic variability on expression of X-linked genes in human monocytes.

Castagné R, Zeller T, Rotival M, Szymczak S, Truong V, Schillert A, Trégouët DA, Münzel T, Ziegler A, Cambien F, Blankenberg S, Tiret L.

Genomics. 2011 Nov;98(5):320-6. doi: 10.1016/j.ygeno.2011.06.009. Epub 2011 Jul 6.

20.

Protein profiling of genomic instability in endometrial cancer.

Gemoll T, Habermann JK, Lahmann J, Szymczak S, Lundgren C, Bündgen NK, Jungbluth T, Nordström B, Becker S, Lomnytska MI, Bruch HP, Ziegler A, Hellman U, Auer G, Roblick UJ, Jörnvall H.

Cell Mol Life Sci. 2012 Jan;69(2):325-33. doi: 10.1007/s00018-011-0752-0. Epub 2011 Jul 8.

PMID:
21739232
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