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Results: 1 to 20 of 145


Gene therapy using therapeutic and diagnostic recombinant oncolytic vaccinia virus GLV-1h153 for management of colorectal peritoneal carcinomatosis.

Eveno C, Mojica K, Ady JW, Thorek DL, Longo V, Belin LJ, Gholami S, Johnsen C, Zanzonico P, Chen N, Yu T, Szalay AA, Fong Y.

Surgery. 2015 Feb;157(2):331-7. doi: 10.1016/j.surg.2014.09.008.


Antigen profiling analysis of vaccinia virus injected canine tumors: oncolytic virus efficiency predicted by boolean models.

Cecil A, Gentschev I, Adelfinger M, Nolte I, Dandekar T, Szalay AA.

Bioengineered. 2014 Sep-Oct;5(5):319-25. doi: 10.4161/bioe.32227.


A silk-elastinlike protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus.

Price DL, Li P, Chen CH, Wong D, Yu Z, Chen NG, Yu YA, Szalay AA, Cappello J, Fong Y, Wong RJ.

Head Neck. 2014 Sep 22. doi: 10.1002/hed.23877. [Epub ahead of print]


Evaluation of a new recombinant oncolytic vaccinia virus strain GLV-5b451 for feline mammary carcinoma therapy.

Adelfinger M, Gentschev I, Grimm de Guibert J, Weibel S, Langbein-Laugwitz J, Härtl B, Murua Escobar H, Nolte I, Chen NG, Aguilar RJ, Yu YA, Zhang Q, Frentzen A, Szalay AA.

PLoS One. 2014 Aug 5;9(8):e104337. doi: 10.1371/journal.pone.0104337. eCollection 2014.


Inducible gene expression in tumors colonized by modified oncolytic vaccinia virus strains.

Stritzker J, Huppertz S, Zhang Q, Geissinger U, Härtl B, Gentschev I, Szalay AA.

J Virol. 2014 Oct;88(19):11556-67. doi: 10.1128/JVI.00681-14. Epub 2014 Jul 23.


Isolated limb perfusion with melphalan, tumour necrosis factor-alpha and oncolytic vaccinia virus improves tumour targeting and prolongs survival in a rat model of advanced extremity sarcoma.

Pencavel TD, Wilkinson MJ, Mansfield DC, Khan AA, Seth R, Karapanagiotou EM, Roulstone V, Aguilar RJ, Chen NG, Szalay AA, Hayes AJ, Harrington KJ.

Int J Cancer. 2015 Feb 15;136(4):965-76. doi: 10.1002/ijc.29059. Epub 2014 Jul 22.


Oncolytic immunotherapy using recombinant vaccinia virus GLV-1h68 kills sorafenib-resistant hepatocellular carcinoma efficiently.

Ady JW, Heffner J, Mojica K, Johnsen C, Belin LJ, Love D, Chen CT, Pugalenthi A, Klein E, Chen NG, Yu YA, Szalay AA, Fong Y.

Surgery. 2014 Aug;156(2):263-9. doi: 10.1016/j.surg.2014.03.031. Epub 2014 Jun 21.


Characterization of metastasis formation and virotherapy in the human C33A cervical cancer model.

Donat U, Rother J, Schäfer S, Hess M, Härtl B, Kober C, Langbein-Laugwitz J, Stritzker J, Chen NG, Aguilar RJ, Weibel S, Szalay AA.

PLoS One. 2014 Jun 2;9(6):e98533. doi: 10.1371/journal.pone.0098533. eCollection 2014.


Oncolytic virotherapy of canine and feline cancer.

Gentschev I, Patil SS, Petrov I, Cappello J, Adelfinger M, Szalay AA.

Viruses. 2014 May 16;6(5):2122-37. doi: 10.3390/v6052122. Review.


Biotherapeutic approaches to target cancer stem cells.

Duggal R, Minev B, Geissinger U, Wang H, Chen NG, Koka PS, Szalay AA.

J Stem Cells. 2013;8(3-4):135-49. doi: jsc.2014.8.3/4.135. Review.


PEG-pHPMAm-based polymeric micelles loaded with doxorubicin-prodrugs in combination antitumor therapy with oncolytic vaccinia viruses.

Ruiz-Hernández E, Hess M, Melen GJ, Theek B, Talelli M, Shi Y, Ozbakir B, Teunissen EA, Ramírez M, Moeckel D, Kiessling F, Storm G, Scheeren HW, Hennink WE, Szalay AA, Stritzker J, Lammers T.

Polym Chem. 2014 Mar 7;(5):1674-1681.


Oncolytic vaccinia virus in combination with radiation shows synergistic antitumor efficacy in pancreatic cancer.

Dai MH, Liu SL, Chen NG, Zhang TP, You L, Q Zhang F, Chou TC, Szalay AA, Fong Y, Zhao YP.

Cancer Lett. 2014 Mar 28;344(2):282-90. doi: 10.1016/j.canlet.2013.11.007. Epub 2013 Dec 7.


Vaccinia virus GLV-1h153 in combination with 131I shows increased efficiency in treating triple-negative breast cancer.

Gholami S, Chen CH, Lou E, Belin LJ, Fujisawa S, Longo VA, Chen NG, Gönen M, Zanzonico PB, Szalay AA, Fong Y.

FASEB J. 2014 Feb;28(2):676-82. doi: 10.1096/fj.13-237222. Epub 2013 Nov 1.


Optical detection and virotherapy of live metastatic tumor cells in body fluids with vaccinia strains.

Wang H, Chen NG, Minev BR, Zimmermann M, Aguilar RJ, Zhang Q, Sturm JB, Fend F, Yu YA, Cappello J, Lauer UM, Szalay AA.

PLoS One. 2013 Sep 3;8(9):e71105. doi: 10.1371/journal.pone.0071105. eCollection 2013.


An oncolytic vaccinia virus expressing the human sodium iodine symporter prolongs survival and facilitates SPECT/CT imaging in an orthotopic model of malignant pleural mesothelioma.

Belin LJ, Ady JW, Lewis C, Marano D, Gholami S, Mojica K, Eveno C, Longo V, Zanzonico PB, Chen NG, Szalay AA, Fong Y.

Surgery. 2013 Sep;154(3):486-95. doi: 10.1016/j.surg.2013.06.004. Epub 2013 Jul 23.


Vaccinia virus expressing bone morphogenetic protein-4 in novel glioblastoma orthotopic models facilitates enhanced tumor regression and long-term survival.

Duggal R, Geissinger U, Zhang Q, Aguilar J, Chen NG, Binda E, Vescovi AL, Szalay AA.

J Transl Med. 2013 Jun 24;11:155. doi: 10.1186/1479-5876-11-155.


Vaccinia virus-mediated expression of human erythropoietin in tumors enhances virotherapy and alleviates cancer-related anemia in mice.

Nguyen DH, Chen NG, Zhang Q, Le HT, Aguilar RJ, Yu YA, Cappello J, Szalay AA.

Mol Ther. 2013 Nov;21(11):2054-62. doi: 10.1038/mt.2013.149. Epub 2013 Jun 14.


Combination of fractionated irradiation with anti-VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium.

Buckel L, Advani SJ, Frentzen A, Zhang Q, Yu YA, Chen NG, Ehrig K, Stritzker J, Mundt AJ, Szalay AA.

Int J Cancer. 2013 Dec 15;133(12):2989-99. doi: 10.1002/ijc.28296. Epub 2013 Aug 5.


Single-agent combinatorial cancer therapy.

Stritzker J, Szalay AA.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8325-6. doi: 10.1073/pnas.1305832110. Epub 2013 May 10. No abstract available.

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