Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2008 1
2017 2
2019 2
2020 1
2021 1
2022 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

8 results

Results by year

Filters applied: . Clear all
Page 1
CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability.
Mircetic J, Camgöz A, Abohawya M, Ding L, Dietzel J, Tobar SG, Paszkowski-Rogacz M, Seidlitz T, Schmäche T, Mehnert MC, Sidorova O, Weitz J, Buchholz F, Stange DE. Mircetic J, et al. Among authors: buchholz f. Small Methods. 2023 Jun;7(6):e2201605. doi: 10.1002/smtd.202201605. Epub 2023 Mar 12. Small Methods. 2023. PMID: 36908010
However, their application in new, more physiologically relevant culturing systems like patient-derived organoids (PDOs) has been much slower. ...De-repression of NDRG1 by KDM1A inhibitors (KDM1Ai) causes inhibition of Wnt signaling and a strong G1 cell cycle arrest …
However, their application in new, more physiologically relevant culturing systems like patient-derived organoids (PDOs) has been muc …
Systems biology of mammalian cell division.
Kittler R, Pelletier L, Buchholz F. Kittler R, et al. Among authors: buchholz f. Cell Cycle. 2008 Jul 15;7(14):2123-8. doi: 10.4161/cc.7.14.6322. Epub 2008 May 21. Cell Cycle. 2008. PMID: 18635956 Review.
High-throughput screening technologies allow the identification of genes and proteins essential for mammalian cell division. However, the underlying complexity and connectivity of different biological processes, such as signal transduction, transcription, tra …
High-throughput screening technologies allow the identification of genes and proteins essential for mammalian cell division …
A Tug-of-War between Cell Shape and Polarity Controls Division Orientation to Ensure Robust Patterning in the Mouse Blastocyst.
Niwayama R, Moghe P, Liu YJ, Fabrèges D, Buchholz F, Piel M, Hiiragi T. Niwayama R, et al. Among authors: buchholz f. Dev Cell. 2019 Dec 2;51(5):564-574.e6. doi: 10.1016/j.devcel.2019.10.012. Epub 2019 Nov 14. Dev Cell. 2019. PMID: 31735668 Free PMC article.
Oriented cell division patterns tissues by modulating cell position and fate. ...Here, we systematically characterize cell division, volume, and shape changes during mouse pre-implantation development by in toto live imaging. ...
Oriented cell division patterns tissues by modulating cell position and fate. ...Here, we systematically characterize …
Correction of a Factor VIII genomic inversion with designer-recombinases.
Lansing F, Mukhametzyanova L, Rojo-Romanos T, Iwasawa K, Kimura M, Paszkowski-Rogacz M, Karpinski J, Grass T, Sonntag J, Schneider PM, Günes C, Hoersten J, Schmitt LT, Rodriguez-Muela N, Knöfler R, Takebe T, Buchholz F. Lansing F, et al. Among authors: buchholz f. Nat Commun. 2022 Jan 20;13(1):422. doi: 10.1038/s41467-022-28080-7. Nat Commun. 2022. PMID: 35058465 Free PMC article.
The Paf1 complex positively regulates enhancer activity in mouse embryonic stem cells.
Ding L, Paszkowski-Rogacz M, Mircetic J, Chakraborty D, Buchholz F. Ding L, et al. Among authors: buchholz f. Life Sci Alliance. 2020 Dec 29;4(3):e202000792. doi: 10.26508/lsa.202000792. Print 2021 Mar. Life Sci Alliance. 2020. PMID: 33376128 Free PMC article.
However, regulation of Paf1C-mediated promoter-proximal pausing is complex and context dependent. In fact, in cancer cell lines, opposing models of Paf1Cs' role in RNAPII pause-release control have been proposed. ...Depletion of Paf1C attenuates the expression of genes reg …
However, regulation of Paf1C-mediated promoter-proximal pausing is complex and context dependent. In fact, in cancer cell lines, oppo …
ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator.
Jahn A, Rane G, Paszkowski-Rogacz M, Sayols S, Bluhm A, Han CT, Draškovič I, Londoño-Vallejo JA, Kumar AP, Buchholz F, Butter F, Kappei D. Jahn A, et al. Among authors: buchholz f. EMBO Rep. 2017 Jun;18(6):929-946. doi: 10.15252/embr.201744095. Epub 2017 May 12. EMBO Rep. 2017. PMID: 28500257 Free PMC article.
Comparative RNAi Screens in Isogenic Human Stem Cells Reveal SMARCA4 as a Differential Regulator.
Güneş C, Paszkowski-Rogacz M, Rahmig S, Khattak S, Camgöz A, Wermke M, Dahl A, Bornhäuser M, Waskow C, Buchholz F. Güneş C, et al. Among authors: buchholz f. Stem Cell Reports. 2019 May 14;12(5):1084-1098. doi: 10.1016/j.stemcr.2019.03.012. Epub 2019 Apr 25. Stem Cell Reports. 2019. PMID: 31031192 Free PMC article.
Large-scale RNAi screens are a powerful approach to identify functions of genes in a cell-type-specific manner. For model organisms, genetically identical (isogenic) cells from different cell types are readily available, making comparative studies meaningful. ...Our …
Large-scale RNAi screens are a powerful approach to identify functions of genes in a cell-type-specific manner. For model organisms, …
The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo.
Korotkevich E, Niwayama R, Courtois A, Friese S, Berger N, Buchholz F, Hiiragi T. Korotkevich E, et al. Among authors: buchholz f. Dev Cell. 2017 Feb 6;40(3):235-247.e7. doi: 10.1016/j.devcel.2017.01.006. Dev Cell. 2017. PMID: 28171747 Free PMC article.
While cell polarity and adhesion play key roles, the decisive cue driving this lineage segregation remains elusive. Here, to study symmetry breaking, we use a reduced system in which isolated blastomeres recapitulate the first lineage segregation. We find that in the 8- …
While cell polarity and adhesion play key roles, the decisive cue driving this lineage segregation remains elusive. Here, to study sy …