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Items: 1 to 20 of 131

1.

TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target.

Ullah MO, Sweet MJ, Mansell A, Kellie S, Kobe B.

J Leukoc Biol. 2016 May 9. pii: jlb.2RI1115-531R. [Epub ahead of print] Review.

PMID:
27162325
2.

Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.

Seow V, Lim J, Cotterell AJ, Yau MK, Xu W, Lohman RJ, Kok WM, Stoermer MJ, Sweet MJ, Reid RC, Suen JY, Fairlie DP.

Sci Rep. 2016 Apr 20;6:24575. doi: 10.1038/srep24575.

3.

The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists.

Chen KW, Bezbradica JS, Groß CJ, Wall AA, Sweet MJ, Stow JL, Schroder K.

Eur J Immunol. 2016 Apr;46(4):1004-10. doi: 10.1002/eji.201545943. Epub 2016 Feb 1.

PMID:
27062120
4.

Influence of Resource Availability on the Foraging Strategies of the Triangle Butterflyfish Chaetodon triangulum in the Maldives.

Chandler JF, Burn D, Berggren P, Sweet MJ.

PLoS One. 2016 Mar 21;11(3):e0151923. doi: 10.1371/journal.pone.0151923. eCollection 2016.

5.

Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases.

Das Gupta K, Shakespear MR, Iyer A, Fairlie DP, Sweet MJ.

Clin Transl Immunology. 2016 Jan 29;5(1):e62. doi: 10.1038/cti.2015.46. eCollection 2016 Jan. Review.

6.

Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages.

Kapetanovic R, Bokil NJ, Achard ME, Ong CL, Peters KM, Stocks CJ, Phan MD, Monteleone M, Schroder K, Irvine KM, Saunders BM, Walker MJ, Stacey KJ, McEwan AG, Schembri MA, Sweet MJ.

FASEB J. 2016 May;30(5):1901-12. doi: 10.1096/fj.201500061. Epub 2016 Feb 2.

PMID:
26839376
7.

The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression.

Ariffin JK, Kapetanovic R, Schaale K, Gatica-Andrades M, Blumenthal A, Schroder K, Sweet MJ.

J Leukoc Biol. 2016 Jan 27. pii: jlb.2AB0815-339R. [Epub ahead of print]

PMID:
26819317
8.

Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen.

Ravasi T, Mavromatis CH, Bokil NJ, Schembri MA, Sweet MJ.

Methods Mol Biol. 2016;1390:145-58. doi: 10.1007/978-1-4939-3335-8_10.

PMID:
26803628
9.

Baseline coral disease surveys within three marine parks in Sabah, Borneo.

Miller J, Sweet MJ, Wood E, Bythell J.

PeerJ. 2015 Nov 3;3:e1391. doi: 10.7717/peerj.1391. eCollection 2015.

10.

Histone Deacetylase Inhibitors Promote Mitochondrial Reactive Oxygen Species Production and Bacterial Clearance by Human Macrophages.

Ariffin JK, das Gupta K, Kapetanovic R, Iyer A, Reid RC, Fairlie DP, Sweet MJ.

Antimicrob Agents Chemother. 2015 Dec 28;60(3):1521-9. doi: 10.1128/AAC.01876-15.

PMID:
26711769
11.

Analysis of the N-terminal region of human MLKL, as well as two distinct MLKL isoforms, reveals new insights into necroptotic cell death.

Arnež KH, Kindlova M, Bokil NJ, Murphy JM, Sweet MJ, Gunčar G.

Biosci Rep. 2015 Dec 24;36(1):e00291. doi: 10.1042/BSR20150246.

12.

Age-Related Shifts in Bacterial Diversity in a Reef Coral.

Williams AD, Brown BE, Putchim L, Sweet MJ.

PLoS One. 2015 Dec 23;10(12):e0144902. doi: 10.1371/journal.pone.0144902. eCollection 2015.

13.

Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer.

D'Souza C, Henriques ST, Wang CK, Cheneval O, Chan LY, Bokil NJ, Sweet MJ, Craik DJ.

Biochemistry. 2016 Jan 19;55(2):396-405. doi: 10.1021/acs.biochem.5b00529. Epub 2016 Jan 6.

PMID:
26685975
14.

Differential Anti-inflammatory Activity of HDAC Inhibitors in Human Macrophages and Rat Arthritis.

Lohman RJ, Iyer A, Fairlie TJ, Cotterell A, Gupta P, Reid RC, Vesey DA, Sweet MJ, Fairlie DP.

J Pharmacol Exp Ther. 2016 Feb;356(2):387-96. doi: 10.1124/jpet.115.229328. Epub 2015 Dec 10.

PMID:
26660228
15.
16.

The role of H4 flagella in Escherichia coli ST131 virulence.

Kakkanat A, Totsika M, Schaale K, Duell BL, Lo AW, Phan MD, Moriel DG, Beatson SA, Sweet MJ, Ulett GC, Schembri MA.

Sci Rep. 2015 Nov 9;5:16149. doi: 10.1038/srep16149.

17.

Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1-Independent Mechanism.

Stammler D, Eigenbrod T, Menz S, Frick JS, Sweet MJ, Shakespear MR, Jantsch J, Siegert I, Wölfle S, Langer JD, Oehme I, Schaefer L, Fischer A, Knievel J, Heeg K, Dalpke AH, Bode KA.

J Immunol. 2015 Dec 1;195(11):5421-31. doi: 10.4049/jimmunol.1501195. Epub 2015 Oct 30.

PMID:
26519528
18.

Deletion of Wntless in myeloid cells exacerbates liver fibrosis and the ductular reaction in chronic liver injury.

Irvine KM, Clouston AD, Gadd VL, Miller GC, Wong WY, Melino M, Maradana MR, MacDonald K, Lang RA, Sweet MJ, Blumenthal A, Powell EE.

Fibrogenesis Tissue Repair. 2015 Oct 15;8:19. doi: 10.1186/s13069-015-0036-7. eCollection 2015.

19.

Uropathogenic Escherichia coli Engages CD14-Dependent Signaling to Enable Bladder-Macrophage-Dependent Control of Acute Urinary Tract Infection.

Carey AJ, Sullivan MJ, Duell BL, Crossman DK, Chattopadhyay D, Brooks AJ, Tan CK, Crowley M, Sweet MJ, Schembri MA, Ulett GC.

J Infect Dis. 2016 Feb 15;213(4):659-68. doi: 10.1093/infdis/jiv424. Epub 2015 Aug 30.

PMID:
26324782
20.

TLR3 drives IRF6-dependent IL-23p19 expression and p19/EBI3 heterodimer formation in keratinocytes.

Ramnath D, Tunny K, Hohenhaus DM, Pitts CM, Bergot AS, Hogarth PM, Hamilton JA, Kapetanovic R, Sturm RA, Scholz GM, Sweet MJ.

Immunol Cell Biol. 2015 Oct;93(9):771-9. doi: 10.1038/icb.2015.77. Epub 2015 Aug 25.

PMID:
26303210
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