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Results: 1 to 20 of 103

1.

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge.

Chen KW, Groß CJ, Sotomayor FV, Stacey KJ, Tschopp J, Sweet MJ, Schroder K.

Cell Rep. 2014 Jul 24;8(2):570-82. doi: 10.1016/j.celrep.2014.06.028. Epub 2014 Jul 17.

PMID:
25043180
[PubMed - in process]
2.

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling.

Luo L, Wall AA, Yeo JC, Condon ND, Norwood SJ, Schoenwaelder S, Chen KW, Jackson S, Jenkins BJ, Hartland EL, Schroder K, Collins BM, Sweet MJ, Stow JL.

Nat Commun. 2014 Jul 15;5:4407. doi: 10.1038/ncomms5407.

PMID:
25022365
[PubMed - in process]
3.

Experimental antibiotic treatment identifies potential pathogens of white band disease in the endangered Caribbean coral Acropora cervicornis.

Sweet MJ, Croquer A, Bythell JC.

Proc Biol Sci. 2014 Aug 7;281(1788). pii: 20140094. doi: 10.1098/rspb.2014.0094.

PMID:
24943374
[PubMed - in process]
Free Article
4.

Interferon Regulatory Factor 6 Differentially Regulates Toll-like Receptor 2-dependent Chemokine Gene Expression in Epithelial Cells.

Kwa MQ, Nguyen T, Huynh J, Ramnath D, De Nardo D, Lam PY, Reynolds EC, Hamilton JA, Sweet MJ, Scholz GM.

J Biol Chem. 2014 Jul 11;289(28):19758-68. doi: 10.1074/jbc.M114.584540. Epub 2014 May 28.

PMID:
24872416
[PubMed - in process]
5.

Towards selective lysophospholipid GPCR modulators.

Archbold JK, Martin JL, Sweet MJ.

Trends Pharmacol Sci. 2014 May;35(5):219-26. doi: 10.1016/j.tips.2014.03.004. Epub 2014 Apr 16.

PMID:
24746475
[PubMed - indexed for MEDLINE]
6.

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis.

Schroder WA, Major LD, Le TT, Gardner J, Sweet MJ, Janciauskiene S, Suhrbier A.

Cancer Med. 2014 Jun;3(3):500-13. doi: 10.1002/cam4.229. Epub 2014 Mar 19.

PMID:
24644264
[PubMed - in process]
Free PMC Article
7.

Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.

Yu CH, Nguyen TT, Irvine KM, Sweet MJ, Frazer IH, Blumenthal A.

Eur J Immunol. 2014 May;44(5):1480-90. doi: 10.1002/eji.201343959. Epub 2014 Mar 7.

PMID:
24643512
[PubMed - indexed for MEDLINE]
8.

Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice.

Koulis C, Chen YC, Hausding C, Ahrens I, Kyaw TS, Tay C, Allen T, Jandeleit-Dahm K, Sweet MJ, Akira S, Bobik A, Peter K, Agrotis A.

Arterioscler Thromb Vasc Biol. 2014 Mar;34(3):516-25. doi: 10.1161/ATVBAHA.113.302407. Epub 2014 Jan 16.

PMID:
24436372
[PubMed - indexed for MEDLINE]
9.

The TLR signalling adaptor TRIF/TICAM-1 has an N-terminal helical domain with structural similarity to IFIT proteins.

Ullah MO, Ve T, Mangan M, Alaidarous M, Sweet MJ, Mansell A, Kobe B.

Acta Crystallogr D Biol Crystallogr. 2013 Dec;69(Pt 12):2420-30. doi: 10.1107/S0907444913022385. Epub 2013 Nov 19.

PMID:
24311583
[PubMed - indexed for MEDLINE]
10.

Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB.

Alaidarous M, Ve T, Casey LW, Valkov E, Ericsson DJ, Ullah MO, Schembri MA, Mansell A, Sweet MJ, Kobe B.

J Biol Chem. 2014 Jan 10;289(2):654-68. doi: 10.1074/jbc.M113.523274. Epub 2013 Nov 21.

PMID:
24265315
[PubMed - indexed for MEDLINE]
11.

Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.

Alaidarous M, Ve T, Ullah MO, Valkov E, Mansell A, Schembri MA, Sweet MJ, Kobe B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1167-70. doi: 10.1107/S1744309113024408. Epub 2013 Sep 28.

PMID:
24100574
[PubMed - indexed for MEDLINE]
12.

Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a.

Seow V, Lim J, Iyer A, Suen JY, Ariffin JK, Hohenhaus DM, Sweet MJ, Fairlie DP.

J Immunol. 2013 Oct 15;191(8):4308-16. doi: 10.4049/jimmunol.1301355. Epub 2013 Sep 16.

PMID:
24043889
[PubMed - indexed for MEDLINE]
13.

An mRNA atlas of G protein-coupled receptor expression during primary human monocyte/macrophage differentiation and lipopolysaccharide-mediated activation identifies targetable candidate regulators of inflammation.

Hohenhaus DM, Schaale K, Le Cao KA, Seow V, Iyer A, Fairlie DP, Sweet MJ.

Immunobiology. 2013 Nov;218(11):1345-53. doi: 10.1016/j.imbio.2013.07.001. Epub 2013 Jul 15.

PMID:
23948647
[PubMed - indexed for MEDLINE]
14.

Algae as reservoirs for coral pathogens.

Sweet MJ, Bythell JC, Nugues MM.

PLoS One. 2013 Jul 31;8(7):e69717. doi: 10.1371/journal.pone.0069717. Print 2013.

PMID:
23936086
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Histone deacetylase 7 promotes Toll-like receptor 4-dependent proinflammatory gene expression in macrophages.

Shakespear MR, Hohenhaus DM, Kelly GM, Kamal NA, Gupta P, Labzin LI, Schroder K, Garceau V, Barbero S, Iyer A, Hume DA, Reid RC, Irvine KM, Fairlie DP, Sweet MJ.

J Biol Chem. 2013 Aug 30;288(35):25362-74. doi: 10.1074/jbc.M113.496281. Epub 2013 Jul 12.

PMID:
23853092
[PubMed - indexed for MEDLINE]
16.

Crystallization and X-ray diffraction analysis of the N-terminal domain of the Toll-like receptor signalling adaptor protein TRIF/TICAM-1.

Ullah MO, Ve T, Dkhar J, Alaidarous M, Ericsson DJ, Sweet MJ, Mansell A, Kobe B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jul;69(Pt 7):766-70. doi: 10.1107/S174430911301419X. Epub 2013 Jun 28.

PMID:
23832204
[PubMed - indexed for MEDLINE]
17.

An antioxidant role for catecholate siderophores in Salmonella.

Achard ME, Chen KW, Sweet MJ, Watts RE, Schroder K, Schembri MA, McEwan AG.

Biochem J. 2013 Sep 15;454(3):543-9.

PMID:
23805839
[PubMed - indexed for MEDLINE]
18.

Metal ions in macrophage antimicrobial pathways: emerging roles for zinc and copper.

Stafford SL, Bokil NJ, Achard ME, Kapetanovic R, Schembri MA, McEwan AG, Sweet MJ.

Biosci Rep. 2013 Jul 16;33(4). pii: e00049. doi: 10.1042/BSR20130014. Review.

PMID:
23738776
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized.

Chen KE, Richards AA, Caradoc-Davies TT, Vajjhala PR, Robin G, Lua LH, Hill JM, Schroder K, Sweet MJ, Kellie S, Kobe B, Martin J.

Acta Crystallogr D Biol Crystallogr. 2013 May;69(Pt 5):774-84. doi: 10.1107/S0907444913001558. Epub 2013 Apr 11.

PMID:
23633586
[PubMed - indexed for MEDLINE]
20.

Differences in the repertoire, regulation and function of Toll-like Receptors and inflammasome-forming Nod-like Receptors between human and mouse.

Ariffin JK, Sweet MJ.

Curr Opin Microbiol. 2013 Jun;16(3):303-10. doi: 10.1016/j.mib.2013.03.002. Epub 2013 Mar 26.

PMID:
23540353
[PubMed - indexed for MEDLINE]

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