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Results: 1 to 20 of 63

1.

E50K-OPTN-induced retinal cell death involves the Rab GTPase-activating protein, TBC1D17 mediated block in autophagy.

Chalasani ML, Kumari A, Radha V, Swarup G.

PLoS One. 2014 Apr 21;9(4):e95758. doi: 10.1371/journal.pone.0095758. eCollection 2014.

PMID:
24752605
[PubMed - in process]
Free PMC Article
2.

IRF-1-binding site in the first intron mediates interferon-γ-induced optineurin promoter activation.

Sudhakar C, Vaibhava V, Swarup G.

Biochem Biophys Res Commun. 2013 Jul 19;437(1):179-84. doi: 10.1016/j.bbrc.2013.06.065. Epub 2013 Jun 27.

PMID:
23811275
[PubMed - indexed for MEDLINE]
3.

A cataract-causing connexin 50 mutant is mislocalized to the ER due to loss of the fourth transmembrane domain and cytoplasmic domain.

Somaraju Chalasani ML, Muppirala M, G Ponnam SP, Kannabiran C, Swarup G.

FEBS Open Bio. 2012 Nov 27;3:22-9. doi: 10.1016/j.fob.2012.11.005. Print 2013.

PMID:
23772370
[PubMed]
Free PMC Article
4.

M98K-OPTN induces transferrin receptor degradation and RAB12-mediated autophagic death in retinal ganglion cells.

Sirohi K, Chalasani ML, Sudhakar C, Kumari A, Radha V, Swarup G.

Autophagy. 2013 Apr;9(4):510-27. doi: 10.4161/auto.23458. Epub 2013 Jan 28.

PMID:
23357852
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Emerging role of tyrosine phosphatase, TCPTP, in the organelles of the early secretory pathway.

Muppirala M, Gupta V, Swarup G.

Biochim Biophys Acta. 2013 May;1833(5):1125-32. doi: 10.1016/j.bbamcr.2013.01.004. Epub 2013 Jan 15. Review.

PMID:
23328081
[PubMed - indexed for MEDLINE]
Free Article
6.

Tyrosine phosphorylation of a SNARE protein, syntaxin 17: implications for membrane trafficking in the early secretory pathway.

Muppirala M, Gupta V, Swarup G.

Biochim Biophys Acta. 2012 Dec;1823(12):2109-19. doi: 10.1016/j.bbamcr.2012.09.003. Epub 2012 Sep 21.

PMID:
23006999
[PubMed - indexed for MEDLINE]
Free Article
7.

Optineurin mediates a negative regulation of Rab8 by the GTPase-activating protein TBC1D17.

Vaibhava V, Nagabhushana A, Chalasani ML, Sudhakar C, Kumari A, Swarup G.

J Cell Sci. 2012 Nov 1;125(Pt 21):5026-39. doi: 10.1242/jcs.102327. Epub 2012 Aug 1.

PMID:
22854040
[PubMed - indexed for MEDLINE]
Free Article
8.

Syntaxin 17 cycles between the ER and ERGIC and is required to maintain the architecture of ERGIC and Golgi.

Muppirala M, Gupta V, Swarup G.

Biol Cell. 2011 Jul;103(7):333-50. doi: 10.1042/BC20110006.

PMID:
21545355
[PubMed - indexed for MEDLINE]
9.

Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation.

Nagabhushana A, Bansal M, Swarup G.

PLoS One. 2011 Mar 7;6(3):e17477. doi: 10.1371/journal.pone.0017477.

PMID:
21408173
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Optineurin, a multifunctional protein involved in glaucoma, amyotrophic lateral sclerosis and antiviral signalling.

Swarup G, Nagabhushana A.

J Biosci. 2010 Dec;35(4):501-5. No abstract available.

PMID:
21289430
[PubMed - indexed for MEDLINE]
Free Article
11.

Regulation of endocytic trafficking of transferrin receptor by optineurin and its impairment by a glaucoma-associated mutant.

Nagabhushana A, Chalasani ML, Jain N, Radha V, Rangaraj N, Balasubramanian D, Swarup G.

BMC Cell Biol. 2010 Jan 19;11:4. doi: 10.1186/1471-2121-11-4.

PMID:
20085643
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Interaction with Sug1 enables Ipaf ubiquitination leading to caspase 8 activation and cell death.

Kumar Y, Radha V, Swarup G.

Biochem J. 2010 Mar 15;427(1):91-104. doi: 10.1042/BJ20091349.

PMID:
20085538
[PubMed - indexed for MEDLINE]
Free Article
13.

Optineurin and its mutants: molecules associated with some forms of glaucoma.

Chalasani ML, Swarup G, Balasubramanian D.

Ophthalmic Res. 2009;42(4):176-84. doi: 10.1159/000232400. Epub 2009 Aug 7. Review.

PMID:
19672125
[PubMed - indexed for MEDLINE]
14.

NF-kappaB mediates tumor necrosis factor alpha-induced expression of optineurin, a negative regulator of NF-kappaB.

Sudhakar C, Nagabhushana A, Jain N, Swarup G.

PLoS One. 2009;4(4):e5114. doi: 10.1371/journal.pone.0005114. Epub 2009 Apr 2.

PMID:
19340308
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Sp1-like sequences mediate human caspase-3 promoter activation by p73 and cisplatin.

Sudhakar C, Jain N, Swarup G.

FEBS J. 2008 May;275(9):2200-13. doi: 10.1111/j.1742-4658.2008.06373.x. Epub 2008 Apr 1.

PMID:
18384375
[PubMed - indexed for MEDLINE]
16.

Focus on molecules: optineurin.

Chalasani ML, Balasubramanian D, Swarup G.

Exp Eye Res. 2008 Jul;87(1):1-2. Epub 2007 Nov 5. No abstract available.

PMID:
18068704
[PubMed - indexed for MEDLINE]
17.

Tumor necrosis factor-alpha-induced caspase-1 gene expression. Role of p73.

Jain N, Sudhakar Ch, Swarup G.

FEBS J. 2007 Sep;274(17):4396-407.

PMID:
17725714
[PubMed - indexed for MEDLINE]
18.

Regulation of p73 by Hck through kinase-dependent and independent mechanisms.

Paliwal P, Radha V, Swarup G.

BMC Mol Biol. 2007 May 30;8:45.

PMID:
17535448
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

C3G is required for c-Abl-induced filopodia and its overexpression promotes filopodia formation.

Radha V, Rajanna A, Mitra A, Rangaraj N, Swarup G.

Exp Cell Res. 2007 Jul 1;313(11):2476-92. Epub 2007 Mar 30. Erratum in: Exp Cell Res. 2007 Sep 10;313(15):3376.

PMID:
17475248
[PubMed - indexed for MEDLINE]
20.

A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

Chalasani ML, Radha V, Gupta V, Agarwal N, Balasubramanian D, Swarup G.

Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1607-14.

PMID:
17389490
[PubMed - indexed for MEDLINE]
Free Article

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