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Results: 1 to 20 of 37


Accelerated progression of chronic lymphocytic leukemia in Eμ-TCL1 mice expressing catalytically inactive RAG1.

Nganga VK, Palmer VL, Naushad H, Kassmeier MD, Anderson DK, Perry GA, Schabla NM, Swanson PC.

Blood. 2013 May 9;121(19):3855-66, S1-16. doi: 10.1182/blood-2012-08-446732. Epub 2013 Mar 15.


Vitamin C promotes maturation of T-cells.

Manning J, Mitchell B, Appadurai DA, Shakya A, Pierce LJ, Wang H, Nganga V, Swanson PC, May JM, Tantin D, Spangrude GJ.

Antioxid Redox Signal. 2013 Dec 10;19(17):2054-67. doi: 10.1089/ars.2012.4988. Epub 2013 Feb 5.


Smoke-induced signal molecules in bone marrow cells from altered low-density lipoprotein receptor-related protein 5 mice.

Ma D, Li Y, Hackfort B, Zhao Y, Xiao J, Swanson PC, Lappe J, Xiao P, Cullen D, Akhter M, Recker R, Xiao GG.

J Proteome Res. 2012 Jul 6;11(7):3548-60. doi: 10.1021/pr2012158. Epub 2012 Jun 4.


Real-time monitoring of RAG-catalyzed DNA cleavage unveils dynamic changes in coding end association with the coding end complex.

Wang G, Dhar K, Swanson PC, Levitus M, Chang Y.

Nucleic Acids Res. 2012 Jul;40(13):6082-96. doi: 10.1093/nar/gks255. Epub 2012 Mar 20.


VprBP binds full-length RAG1 and is required for B-cell development and V(D)J recombination fidelity.

Kassmeier MD, Mondal K, Palmer VL, Raval P, Kumar S, Perry GA, Anderson DK, Ciborowski P, Jackson S, Xiong Y, Swanson PC.

EMBO J. 2012 Feb 15;31(4):945-58. doi: 10.1038/emboj.2011.455. Epub 2011 Dec 13.


Mechanistic basis for RAG discrimination between recombination sites and the off-target sites of human lymphomas.

Shimazaki N, Askary A, Swanson PC, Lieber MR.

Mol Cell Biol. 2012 Jan;32(2):365-75. doi: 10.1128/MCB.06187-11. Epub 2011 Nov 7.


Accumulation of B1-like B cells in transgenic mice over-expressing catalytically inactive RAG1 in the periphery.

Hassaballa AE, Palmer VL, Anderson DK, Kassmeier MD, Nganga VK, Parks KW, Volkmer DL, Perry GA, Swanson PC.

Immunology. 2011 Dec;134(4):469-86. doi: 10.1111/j.1365-2567.2011.03509.x.


N-acetylcysteine increases the frequency of bone marrow pro-B/pre-B cells, but does not reverse cigarette smoking-induced loss of this subset.

Palmer VL, Kassmeier MD, Willcockson J, Akhter MP, Cullen DM, Swanson PC.

PLoS One. 2011;6(9):e24804. doi: 10.1371/journal.pone.0024804. Epub 2011 Sep 16.


V(D)J recombination: mechanisms of initiation.

Schatz DG, Swanson PC.

Annu Rev Genet. 2011;45:167-202. doi: 10.1146/annurev-genet-110410-132552. Epub 2011 Aug 19. Review.


Cigarette smoke-induced effects on bone marrow B-cell subsets and CD4+:CD8+ T-cell ratios are reversed by smoking cessation: influence of bone mass on immune cell response to and recovery from smoke exposure.

Fusby JS, Kassmeier MD, Palmer VL, Perry GA, Anderson DK, Hackfort BT, Alvarez GK, Cullen DM, Akhter MP, Swanson PC.

Inhal Toxicol. 2010 Aug;22(9):785-96. doi: 10.3109/08958378.2010.483258.


Early steps of V(D)J rearrangement: insights from biochemical studies of RAG-RSS complexes.

Swanson PC, Kumar S, Raval P.

Adv Exp Med Biol. 2009;650:1-15. Review.


Molecular mechanism underlying RAG1/RAG2 synaptic complex formation.

Shlyakhtenko LS, Gilmore J, Kriatchko AN, Kumar S, Swanson PC, Lyubchenko YL.

J Biol Chem. 2009 Jul 31;284(31):20956-65. doi: 10.1074/jbc.M109.028977. Epub 2009 Jun 5.


HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex.

Zhang M, Swanson PC.

BMC Mol Biol. 2009 Mar 24;10:24. doi: 10.1186/1471-2199-10-24.


Full-length RAG1 promotes contact with coding and intersignal sequences in RAG protein complexes bound to recombination signals paired in cis.

Kumar S, Swanson PC.

Nucleic Acids Res. 2009 Apr;37(7):2211-26. doi: 10.1093/nar/gkp047. Epub 2009 Feb 20.


A biochemically defined system for coding joint formation in V(D)J recombination.

Lu H, Shimazaki N, Raval P, Gu J, Watanabe G, Schwarz K, Swanson PC, Lieber MR.

Mol Cell. 2008 Aug 22;31(4):485-97. doi: 10.1016/j.molcel.2008.05.029.


HMG-box domain stimulation of RAG1/2 cleavage activity is metal ion dependent.

Kriatchko AN, Bergeron S, Swanson PC.

BMC Mol Biol. 2008 Apr 1;9:32. doi: 10.1186/1471-2199-9-32.


Evidence for Ku70/Ku80 association with full-length RAG1.

Raval P, Kriatchko AN, Kumar S, Swanson PC.

Nucleic Acids Res. 2008 Apr;36(6):2060-72. doi: 10.1093/nar/gkn049. Epub 2008 Feb 14.


V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies.

Zhang M, Swanson PC.

J Biol Chem. 2008 Mar 14;283(11):6717-27. doi: 10.1074/jbc.M710301200. Epub 2008 Jan 9.


Fluorescence resonance energy transfer analysis of recombination signal sequence configuration in the RAG1/2 synaptic complex.

Ciubotaru M, Kriatchko AN, Swanson PC, Bright FV, Schatz DG.

Mol Cell Biol. 2007 Jul;27(13):4745-58. Epub 2007 Apr 30.

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