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Results: 1 to 20 of 127

1.

The mu-subunit of Plasmodium falciparum clathrin-associated adaptor protein 2 modulates in vitro parasite response to artemisinin and quinine.

Henriques G, van Schalkwyk DA, Burrow R, Warhurst DC, Thompson E, Baker DA, Fidock DA, Hallett R, Flueck C, Sutherland CJ.

Antimicrob Agents Chemother. 2015 Feb 17. pii: AAC.04067-14. [Epub ahead of print]

PMID:
25691625
[PubMed - as supplied by publisher]
2.

Temporal trends in prevalence of Plasmodium falciparum drug resistance alleles over two decades of changing antimalarial policy in coastal Kenya.

Okombo J, Kamau AW, Marsh K, Sutherland CJ, Ochola-Oyier LI.

Int J Parasitol Drugs Drug Resist. 2014 Aug 7;4(3):152-63. doi: 10.1016/j.ijpddr.2014.07.003. eCollection 2014 Dec.

PMID:
25516825
[PubMed]
Free PMC Article
3.

Identification and Deconvolution of Cross-Resistance Signals from Antimalarial Compounds Using Multidrug-Resistant Plasmodium falciparum Strains.

Chugh M, Scheurer C, Sax S, Bilsland E, van Schalkwyk DA, Wicht KJ, Hofmann N, Sharma A, Bashyam S, Singh S, Oliver SG, Egan TJ, Malhotra P, Sutherland CJ, Beck HP, Wittlin S, Spangenberg T, Ding XC.

Antimicrob Agents Chemother. 2015 Feb;59(2):1110-8. doi: 10.1128/AAC.03265-14. Epub 2014 Dec 8.

PMID:
25487796
[PubMed - in process]
Free Article
4.

Detection of single-nucleotide polymorphisms in Plasmodium falciparum by PCR primer extension and lateral flow immunoassay.

Moers AP, Hallett RL, Burrow R, Schallig HD, Sutherland CJ, van Amerongen A.

Antimicrob Agents Chemother. 2015 Jan;59(1):365-71. doi: 10.1128/AAC.03395-14. Epub 2014 Nov 3.

PMID:
25367901
[PubMed - in process]
5.

Alternatively spliced transcripts and novel pseudogenes of the Plasmodium falciparum resistance-associated locus pfcrt detected in East African malaria patients.

Gadalla NB, Malmberg M, Adam I, Oguike MC, Beshir K, Elzaki SE, Mukhtar I, Gadalla AA, Warhurst DC, Ngasala B, Mårtensson A, El-Sayed BB, Gil JP, Sutherland CJ.

J Antimicrob Chemother. 2015 Jan;70(1):116-23. doi: 10.1093/jac/dku358. Epub 2014 Sep 24.

PMID:
25253286
[PubMed - in process]
Free PMC Article
6.

Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.

Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TM, Ménard D, Adam I, Ademowo G, Arze C, Baliraine FN, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé AA, El-Sayed BB, Eshetu T, Eyase F, Falade C, Faucher JF, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel JR, Kironde F, Kofoed PE, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya SL, Nzila A, Oguike M, Otienoburu SD, Ogutu B, Ouédraogo JB, Piola P, Rombo L, Schramm B, Somé AF, Thwing J, Ursing J, Wong RP, Zeynudin A, Zongo I, Plowe CV, Sibley CH; ASAQ Molecular Marker Study Group; WWARN AL.

Am J Trop Med Hyg. 2014 Oct;91(4):833-43. doi: 10.4269/ajtmh.14-0031. Epub 2014 Jul 21.

PMID:
25048375
[PubMed - in process]
Free PMC Article
7.

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.

Henriques G, Hallett RL, Beshir KB, Gadalla NB, Johnson RE, Burrow R, van Schalkwyk DA, Sawa P, Omar SA, Clark TG, Bousema T, Sutherland CJ.

J Infect Dis. 2014 Dec 15;210(12):2001-8. doi: 10.1093/infdis/jiu358. Epub 2014 Jul 3.

PMID:
24994911
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A barcode of organellar genome polymorphisms identifies the geographic origin of Plasmodium falciparum strains.

Preston MD, Campino S, Assefa SA, Echeverry DF, Ocholla H, Amambua-Ngwa A, Stewart LB, Conway DJ, Borrmann S, Michon P, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Pain A, Bousema T, Drakeley CJ, Fairhurst RM, Sutherland CJ, Roper C, Clark TG.

Nat Commun. 2014 Jun 13;5:4052. doi: 10.1038/ncomms5052.

PMID:
24923250
[PubMed - in process]
Free PMC Article
9.

Detection of persistent Plasmodium spp. infections in Ugandan children after artemether-lumefantrine treatment.

Betson M, Sousa-Figueiredo JC, Atuhaire A, Arinaitwe M, Adriko M, Mwesigwa G, Nabonge J, Kabatereine NB, Sutherland CJ, Stothard JR.

Parasitology. 2014 Dec;141(14):1880-90. doi: 10.1017/S003118201400033X. Epub 2014 May 16.

PMID:
24837880
[PubMed - in process]
Free PMC Article
10.

African origin of the malaria parasite Plasmodium vivax.

Liu W, Li Y, Shaw KS, Learn GH, Plenderleith LJ, Malenke JA, Sundararaman SA, Ramirez MA, Crystal PA, Smith AG, Bibollet-Ruche F, Ayouba A, Locatelli S, Esteban A, Mouacha F, Guichet E, Butel C, Ahuka-Mundeke S, Inogwabini BI, Ndjango JB, Speede S, Sanz CM, Morgan DB, Gonder MK, Kranzusch PJ, Walsh PD, Georgiev AV, Muller MN, Piel AK, Stewart FA, Wilson ML, Pusey AE, Cui L, Wang Z, Färnert A, Sutherland CJ, Nolder D, Hart JA, Hart TB, Bertolani P, Gillis A, LeBreton M, Tafon B, Kiyang J, Djoko CF, Schneider BS, Wolfe ND, Mpoudi-Ngole E, Delaporte E, Carter R, Culleton RL, Shaw GM, Rayner JC, Peeters M, Hahn BH, Sharp PM.

Nat Commun. 2014;5:3346. doi: 10.1038/ncomms4346.

PMID:
24557500
[PubMed - in process]
Free PMC Article
11.

Persistent detection of Plasmodium falciparum, P. malariae, P. ovale curtisi and P. ovale wallikeri after ACT treatment of asymptomatic Ghanaian school-children.

Dinko B, Oguike MC, Larbi JA, Bousema T, Sutherland CJ.

Int J Parasitol Drugs Drug Resist. 2013 Jan 19;3:45-50. doi: 10.1016/j.ijpddr.2013.01.001. eCollection 2013 Dec.

PMID:
24533292
[PubMed]
Free PMC Article
12.

Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections.

Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD.

Malar J. 2014 Feb 11;13:53. doi: 10.1186/1475-2875-13-53.

PMID:
24517452
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

estMOI: estimating multiplicity of infection using parasite deep sequencing data.

Assefa SA, Preston MD, Campino S, Ocholla H, Sutherland CJ, Clark TG.

Bioinformatics. 2014 May 1;30(9):1292-4. doi: 10.1093/bioinformatics/btu005. Epub 2014 Jan 17.

PMID:
24443379
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

PlasmoView: a web-based resource to visualise global Plasmodium falciparum genomic variation.

Preston MD, Assefa SA, Ocholla H, Sutherland CJ, Borrmann S, Nzila A, Michon P, Hien TT, Bousema T, Drakeley CJ, Zongo I, Ouédraogo JB, Djimde AA, Doumbo OK, Nosten F, Fairhurst RM, Conway DJ, Roper C, Clark TG.

J Infect Dis. 2014 Jun 1;209(11):1808-15. doi: 10.1093/infdis/jit812. Epub 2013 Dec 12.

PMID:
24338354
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection.

Nwakanma DC, Duffy CW, Amambua-Ngwa A, Oriero EC, Bojang KA, Pinder M, Drakeley CJ, Sutherland CJ, Milligan PJ, Macinnis B, Kwiatkowski DP, Clark TG, Greenwood BM, Conway DJ.

J Infect Dis. 2014 Apr 1;209(7):1126-35. doi: 10.1093/infdis/jit618. Epub 2013 Nov 21.

PMID:
24265439
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Repeat polymorphisms in the low-complexity regions of Plasmodium falciparum ABC transporters and associations with in vitro antimalarial responses.

Okombo J, Abdi AI, Kiara SM, Mwai L, Pole L, Sutherland CJ, Nzila A, Ochola-Oyier LI.

Antimicrob Agents Chemother. 2013 Dec;57(12):6196-204. doi: 10.1128/AAC.01465-13. Epub 2013 Sep 30.

PMID:
24080667
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Genetic marker suitable for identification and genotyping of Plasmodium ovale curtisi and Plasmodium ovale wallikeri.

Tanomsing N, Imwong M, Sutherland CJ, Dolecek C, Hien TT, Nosten F, Day NP, White NJ, Snounou G.

J Clin Microbiol. 2013 Dec;51(12):4213-6. doi: 10.1128/JCM.01527-13. Epub 2013 Sep 25.

PMID:
24068009
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Culture-adapted Plasmodium falciparum isolates from UK travellers: in vitro drug sensitivity, clonality and drug resistance markers.

van Schalkwyk DA, Burrow R, Henriques G, Gadalla NB, Beshir KB, Hasford C, Wright SG, Ding XC, Chiodini PL, Sutherland CJ.

Malar J. 2013 Sep 13;12:320. doi: 10.1186/1475-2875-12-320.

PMID:
24028570
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Residual Plasmodium falciparum parasitemia in Kenyan children after artemisinin-combination therapy is associated with increased transmission to mosquitoes and parasite recurrence.

Beshir KB, Sutherland CJ, Sawa P, Drakeley CJ, Okell L, Mweresa CK, Omar SA, Shekalaghe SA, Kaur H, Ndaro A, Chilongola J, Schallig HD, Sauerwein RW, Hallett RL, Bousema T.

J Infect Dis. 2013 Dec 15;208(12):2017-24. doi: 10.1093/infdis/jit431. Epub 2013 Aug 14.

PMID:
23945376
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Selection of pfdhfr/pfdhps alleles and declining artesunate/sulphadoxine-pyrimethamine efficacy against Plasmodium falciparum eight years after deployment in eastern Sudan.

Gadalla NB, Abdallah TM, Atwal S, Sutherland CJ, Adam I.

Malar J. 2013 Jul 19;12:255. doi: 10.1186/1475-2875-12-255.

PMID:
23870667
[PubMed - indexed for MEDLINE]
Free PMC Article
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