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Results: 1 to 20 of 56

1.

The SH2 domain regulates c-Abl kinase activation by a cyclin-like mechanism and remodulation of the hinge motion.

Dölker N, Górna MW, Sutto L, Torralba AS, Superti-Furga G, Gervasio FL.

PLoS Comput Biol. 2014 Oct 9;10(10):e1003863. doi: 10.1371/journal.pcbi.1003863. eCollection 2014 Oct.

PMID:
25299346
[PubMed - in process]
Free PMC Article
2.

The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production.

Eberle CA, Zayas M, Stukalov A, Pichlmair A, Alvisi G, Müller AC, Bennett KL, Bartenschlager R, Superti-Furga G.

Virology. 2014 Aug;462-463:34-41. doi: 10.1016/j.virol.2014.05.016. Epub 2014 Jun 14.

PMID:
25092459
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Building and exploring an integrated human kinase network: global organization and medical entry points.

Colinge J, César-Razquin A, Huber K, Breitwieser FP, Májek P, Superti-Furga G.

J Proteomics. 2014 Jul 31;107:113-27. doi: 10.1016/j.jprot.2014.03.028. Epub 2014 Apr 3.

PMID:
24704859
[PubMed - in process]
Free PMC Article
4.

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.

Huber KV, Salah E, Radic B, Gridling M, Elkins JM, Stukalov A, Jemth AS, Göktürk C, Sanjiv K, Strömberg K, Pham T, Berglund UW, Colinge J, Bennett KL, Loizou JI, Helleday T, Knapp S, Superti-Furga G.

Nature. 2014 Apr 10;508(7495):222-7. doi: 10.1038/nature13194. Epub 2014 Apr 2.

PMID:
24695225
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

IFITs: Emerging Roles as Key Anti-Viral Proteins.

Vladimer GI, Górna MW, Superti-Furga G.

Front Immunol. 2014 Mar 10;5:94. doi: 10.3389/fimmu.2014.00094. eCollection 2014. Review.

PMID:
24653722
[PubMed]
Free PMC Article
6.

Virulence factor NSs of rift valley fever virus recruits the F-box protein FBXO3 to degrade subunit p62 of general transcription factor TFIIH.

Kainulainen M, Habjan M, Hubel P, Busch L, Lau S, Colinge J, Superti-Furga G, Pichlmair A, Weber F.

J Virol. 2014 Mar;88(6):3464-73. doi: 10.1128/JVI.02914-13. Epub 2014 Jan 8.

PMID:
24403578
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection.

Liehl P, Zuzarte-Luís V, Chan J, Zillinger T, Baptista F, Carapau D, Konert M, Hanson KK, Carret C, Lassnig C, Müller M, Kalinke U, Saeed M, Chora AF, Golenbock DT, Strobl B, Prudêncio M, Coelho LP, Kappe SH, Superti-Furga G, Pichlmair A, Vigário AM, Rice CM, Fitzgerald KA, Barchet W, Mota MM.

Nat Med. 2014 Jan;20(1):47-53. doi: 10.1038/nm.3424. Epub 2013 Dec 22.

PMID:
24362933
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.

Li J, Bennett K, Stukalov A, Fang B, Zhang G, Yoshida T, Okamoto I, Kim JY, Song L, Bai Y, Qian X, Rawal B, Schell M, Grebien F, Winter G, Rix U, Eschrich S, Colinge J, Koomen J, Superti-Furga G, Haura EB.

Mol Syst Biol. 2013 Nov 5;9:705. doi: 10.1038/msb.2013.61.

PMID:
24189400
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A target-disease network model of second-generation BCR-ABL inhibitor action in Ph+ ALL.

Rix U, Colinge J, Blatt K, Gridling M, Remsing Rix LL, Parapatics K, Cerny-Reiterer S, Burkard TR, Jäger U, Melo JV, Bennett KL, Valent P, Superti-Furga G.

PLoS One. 2013 Oct 10;8(10):e77155. doi: 10.1371/journal.pone.0077155. eCollection 2013.

PMID:
24130846
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Affinity purification strategies for proteomic analysis of transcription factor complexes.

Giambruno R, Grebien F, Stukalov A, Knoll C, Planyavsky M, Rudashevskaya EL, Colinge J, Superti-Furga G, Bennett KL.

J Proteome Res. 2013 Sep 6;12(9):4018-27. doi: 10.1021/pr4003323. Epub 2013 Aug 22.

PMID:
23937658
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The CRAPome: a contaminant repository for affinity purification-mass spectrometry data.

Mellacheruvu D, Wright Z, Couzens AL, Lambert JP, St-Denis NA, Li T, Miteva YV, Hauri S, Sardiu ME, Low TY, Halim VA, Bagshaw RD, Hubner NC, Al-Hakim A, Bouchard A, Faubert D, Fermin D, Dunham WH, Goudreault M, Lin ZY, Badillo BG, Pawson T, Durocher D, Coulombe B, Aebersold R, Superti-Furga G, Colinge J, Heck AJ, Choi H, Gstaiger M, Mohammed S, Cristea IM, Bennett KL, Washburn MP, Raught B, Ewing RM, Gingras AC, Nesvizhskii AI.

Nat Methods. 2013 Aug;10(8):730-6. doi: 10.1038/nmeth.2557. Epub 2013 Jul 7.

PMID:
23921808
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Experimental characterization of the human non-sequence-specific nucleic acid interactome.

Dürnberger G, Bürckstümmer T, Huber K, Giambruno R, Doerks T, Karayel E, Burkard TR, Kaupe I, Müller AC, Schönegger A, Ecker GF, Lohninger H, Bork P, Bennett KL, Superti-Furga G, Colinge J.

Genome Biol. 2013 Jul 31;14(7):R81. doi: 10.1186/gb-2013-14-7-r81.

PMID:
23902751
[PubMed - in process]
Free PMC Article
13.

A miniaturized chemical proteomic approach for target profiling of clinical kinase inhibitors in tumor biopsies.

Chamrád I, Rix U, Stukalov A, Gridling M, Parapatics K, Müller AC, Altiok S, Colinge J, Superti-Furga G, Haura EB, Bennett KL.

J Proteome Res. 2013 Sep 6;12(9):4005-17. doi: 10.1021/pr400309p. Epub 2013 Aug 20.

PMID:
23901793
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

FAM111A mutations result in hypoparathyroidism and impaired skeletal development.

Unger S, Górna MW, Le Béchec A, Do Vale-Pereira S, Bedeschi MF, Geiberger S, Grigelioniene G, Horemuzova E, Lalatta F, Lausch E, Magnani C, Nampoothiri S, Nishimura G, Petrella D, Rojas-Ringeling F, Utsunomiya A, Zabel B, Pradervand S, Harshman K, Campos-Xavier B, Bonafé L, Superti-Furga G, Stevenson B, Superti-Furga A.

Am J Hum Genet. 2013 Jun 6;92(6):990-5. doi: 10.1016/j.ajhg.2013.04.020. Epub 2013 May 16.

PMID:
23684011
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Cell biology: a key driver of therapeutic innovation.

Hantschel O, Superti-Furga G.

J Cell Biol. 2012 Nov 12;199(4):571-5. doi: 10.1083/jcb.201208111.

PMID:
23148230
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

Winter GE, Rix U, Carlson SM, Gleixner KV, Grebien F, Gridling M, Müller AC, Breitwieser FP, Bilban M, Colinge J, Valent P, Bennett KL, White FM, Superti-Furga G.

Nat Chem Biol. 2012 Nov;8(11):905-12. doi: 10.1038/nchembio.1085. Epub 2012 Sep 30.

PMID:
23023260
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The growing arsenal of ATP-competitive and allosteric inhibitors of BCR-ABL.

Hantschel O, Grebien F, Superti-Furga G.

Cancer Res. 2012 Oct 1;72(19):4890-5. doi: 10.1158/0008-5472.CAN-12-1276. Epub 2012 Sep 21. Review.

PMID:
23002203
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Mig6 is a sensor of EGF receptor inactivation that directly activates c-Abl to induce apoptosis during epithelial homeostasis.

Hopkins S, Linderoth E, Hantschel O, Suarez-Henriques P, Pilia G, Kendrick H, Smalley MJ, Superti-Furga G, Ferby I.

Dev Cell. 2012 Sep 11;23(3):547-59. doi: 10.1016/j.devcel.2012.08.001.

PMID:
22975324
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Optimisation of Downscaled Tandem Affinity Purifications to Identify Core Protein Complexes.

Haura EB, Sacco R, Li J, Müller AC, Grebien F, Superti-Furga G, Bennett KL.

J Integr OMICS. 2012 May;2(1):55-68.

PMID:
24077984
[PubMed]
Free PMC Article
20.

Targeting allosteric regulatory modules in oncoproteins: "drugging the undruggable".

Hantschel O, Grebien F, Superti-Furga G.

Oncotarget. 2011 Nov;2(11):828-9. No abstract available.

PMID:
22084171
[PubMed - indexed for MEDLINE]
Free PMC Article

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