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Year Number of Results
1987 2
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2007 1
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2012 7
2013 5
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99 results

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Page 1
Sulfuretin exerts anti-depressive effects in the lipopolysaccharide-induced depressive mouse models.
Sun X, Jiang X, Li X, Qi Z, Lu Y. Sun X, et al. Physiol Behav. 2022 Jun 1;250:113800. doi: 10.1016/j.physbeh.2022.113800. Epub 2022 Apr 5. Physiol Behav. 2022. PMID: 35395250
SL327 was used to block the ERK pathway in mice to evaluate the interaction between Sulfuretin and the ERK pathway. Mice were treated with Sulfuretin for 14 days before lipopolysaccharide (LPS) injection (0.83 mg/kg/day, i.p.) for two days. ...Blocking the p-ERK sig …
SL327 was used to block the ERK pathway in mice to evaluate the interaction between Sulfuretin and the ERK pathway. Mice were treated …
Sulfuretin exerts diversified functions in the processing of amyloid precursor protein.
Chen J, Luo B, Zhong BR, Li KY, Wen QX, Song L, Xiang XJ, Zhou GF, Hu LT, Deng XJ, Ma YL, Chen GJ. Chen J, et al. Genes Dis. 2020 Nov 21;8(6):867-881. doi: 10.1016/j.gendis.2020.11.008. eCollection 2021 Nov. Genes Dis. 2020. PMID: 34522714 Free PMC article.
Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and inflammation. ...We found that sulfuretin increased the levels of the immature but not the mature form of ADAM10 protein. ...
Sulfuretin is a flavonoid that protects cell from damage induced by reactive oxygen species and inflammation. ...We found that sul …
Characterization of sulfuretin as a depigmenting agent.
Zhou Z, Hou J, Xiong J, Li M. Zhou Z, et al. Fundam Clin Pharmacol. 2019 Apr;33(2):208-215. doi: 10.1111/fcp.12414. Epub 2018 Sep 30. Fundam Clin Pharmacol. 2019. PMID: 30216535
When tested in melanoma B16 cells treated with forskolin or alpha-MSH, sulfuretin inhibited the cellular melanogenesis. Sulfuretin also showed direct inhibitory effect on tyrosinase activity in vitro. In human primary melanocytes, the inhibitory effect of sulfure …
When tested in melanoma B16 cells treated with forskolin or alpha-MSH, sulfuretin inhibited the cellular melanogenesis. Sulfuretin …
Sulfuretin Prevents Obesity and Metabolic Diseases in Diet Induced Obese Mice.
Kim S, Song NJ, Chang SH, Bahn G, Choi Y, Rhee DK, Yun UJ, Choi J, Lee J, Yoo JH, Shin D, Park KM, Kang H, Lee S, Ku JM, Cho YS, Park KW. Kim S, et al. Biomol Ther (Seoul). 2019 Jan 1;27(1):107-116. doi: 10.4062/biomolther.2018.090. Biomol Ther (Seoul). 2019. PMID: 30130954 Free PMC article.
Sulfuretin elevated Atf3 mRNA and protein levels in white adipose tissue and adipocytes. Consistently, deficiency of Atf3 promoted lipid accumulation and the expression of adipocyte markers. Sulfuretin's but not resveratrol's anti-adipogenic effects were diminished …
Sulfuretin elevated Atf3 mRNA and protein levels in white adipose tissue and adipocytes. Consistently, deficiency of Atf3 promoted li …
Sulfuretin Attenuates MPP+-Induced Neurotoxicity through Akt/GSK3beta and ERK Signaling Pathways.
Pariyar R, Lamichhane R, Jung HJ, Kim SY, Seo J. Pariyar R, et al. Int J Mol Sci. 2017 Dec 19;18(12):2753. doi: 10.3390/ijms18122753. Int J Mol Sci. 2017. PMID: 29257079 Free PMC article.
Pharmacological inhibitors of PI3K/Akt and ERK abolished the cytoprotective effects of sulfuretin against MPP+. An inhibitor of GSK3beta mimicked sulfuretin-induced protection against MPP+. ...Our findings suggest that sulfuretin might be one of the potential …
Pharmacological inhibitors of PI3K/Akt and ERK abolished the cytoprotective effects of sulfuretin against MPP+. An inhibitor of GSK3b …
Sulfuretin induces osteoblast differentiation through activation of TGF-beta signaling.
Song NJ, Kwon SM, Kim S, Yoon HJ, Seo CR, Jang B, Chang SH, Ku JM, Lee JS, Park KM, Hong JW, Kim GH, Park KW. Song NJ, et al. Mol Cell Biochem. 2015 Dec;410(1-2):55-63. doi: 10.1007/s11010-015-2537-5. Epub 2015 Aug 11. Mol Cell Biochem. 2015. PMID: 26260053
Pro-osteogenic effects of sulfuretin were consistently observed in freshly isolated primary bone marrow cells. ...Together, these data indicate that the pro-osteogenic effects of sulfuretin are mediated through activation of TGF-beta signaling, further supporting th …
Pro-osteogenic effects of sulfuretin were consistently observed in freshly isolated primary bone marrow cells. ...Together, these dat …
Sulfuretin alleviates atopic dermatitis-like symptoms in mice via suppressing Th2 cell activity.
Jiang P, Sun H. Jiang P, et al. Immunol Res. 2018 Oct;66(5):611-619. doi: 10.1007/s12026-018-9025-4. Immunol Res. 2018. PMID: 30159861
Mechanistic study suggested sulfuretin attenuated Th2 cytokine production by suppressing GATA3 expression. Our results demonstrate that sulfuretin could be used as therapeutic application for treating AD....
Mechanistic study suggested sulfuretin attenuated Th2 cytokine production by suppressing GATA3 expression. Our results demonstrate th …
Sulfuretin, a major flavonoid isolated from Rhus verniciflua, ameliorates experimental arthritis in mice.
Lee YR, Hwang JK, Koh HW, Jang KY, Lee JH, Park JW, Park BH. Lee YR, et al. Life Sci. 2012 May 22;90(19-20):799-807. doi: 10.1016/j.lfs.2012.04.015. Epub 2012 Apr 12. Life Sci. 2012. PMID: 22521292
AIM: Sulfuretin, a major flavonoid isolated from Rhus verniciflua, is known to have anti-inflammatory effects. However, the mechanisms underlying the anti-inflammatory effect of sulfuretin on rheumatoid arthritis have not been elucidated. In this study we investigat …
AIM: Sulfuretin, a major flavonoid isolated from Rhus verniciflua, is known to have anti-inflammatory effects. However, the mechanism …
Sulfuretin promotes osteoblastic differentiation in primary cultured osteoblasts and in vivo bone healing.
Auh QS, Park KR, Yun HM, Lim HC, Kim GH, Lee DS, Kim YC, Oh H, Kim EC. Auh QS, et al. Oncotarget. 2016 Nov 29;7(48):78320-78330. doi: 10.18632/oncotarget.12460. Oncotarget. 2016. PMID: 27713171 Free PMC article.
The expression levels of Runx2, BMP-2, and phospho-Smad1/5/8 were upregulated by sulfuretin. Moreover, sulfuretin increased phosphorylation of Akt, mTOR, ERK, and JNK. Furthermore, sulfuretin treatment increased mRNA expression of Wnt ligands, phosphorylation …
The expression levels of Runx2, BMP-2, and phospho-Smad1/5/8 were upregulated by sulfuretin. Moreover, sulfuretin increased ph …
Sulfuretin attenuates allergic airway inflammation in mice.
Song MY, Jeong GS, Lee HS, Kwon KS, Lee SM, Park JW, Kim YC, Park BH. Song MY, et al. Biochem Biophys Res Commun. 2010 Sep 10;400(1):83-8. doi: 10.1016/j.bbrc.2010.08.014. Epub 2010 Aug 7. Biochem Biophys Res Commun. 2010. PMID: 20696133
We isolated sulfuretin from R. verniciflua. Sulfuretin was delivered intraperitoneally after the last ovalbumin challenge. ...The protective effect of sulfuretin was mediated by the inhibition of the NF-kappaB signaling pathway. ...
We isolated sulfuretin from R. verniciflua. Sulfuretin was delivered intraperitoneally after the last ovalbumin challenge. ... …
99 results