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Items: 1 to 20 of 107

1.

Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.

Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG.

PLoS One. 2016 Jun 21;11(6):e0158190. doi: 10.1371/journal.pone.0158190. eCollection 2016.

2.

Efficacy and safety of ustekinumab treatment in adults with moderate-to-severe atopic dermatitis.

Khattri S, Brunner PM, Garcet S, Finney R, Cohen SR, Oliva M, Dutt R, Fuentes-Duculan J, Zheng X, Li X, Bonifacio KM, Kunjravia N, Coats I, Cueto I, Gilleaudeau P, Sullivan-Whalen M, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E.

Exp Dermatol. 2016 Jun 15. doi: 10.1111/exd.13112. [Epub ahead of print]

PMID:
27304428
3.

The spectrum of mild-to-severe psoriasis vulgaris is defined by a common activation of IL-17 pathway genes, but with key differences in immune regulatory genes.

Kim J, Bissonnette R, Lee J, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 May 13. pii: S0022-202X(16)31241-6. doi: 10.1016/j.jid.2016.04.032. [Epub ahead of print]

PMID:
27185339
4.

Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris.

Bissonnette R, Suárez-Fariñas M, Li X, Bonifacio KM, Brodmerkel C, Fuentes-Duculan J, Krueger JG.

PLoS One. 2016 May 6;11(5):e0155215. doi: 10.1371/journal.pone.0155215. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0158190.

5.

Tofacitinib attenuates pathologic immune pathways in patients with psoriasis: A randomized phase 2 study.

Krueger J, Clark JD, Suárez-Fariñas M, Fuentes-Duculan J, Cueto I, Wang CQ, Tan H, Wolk R, Rottinghaus ST, Whitley MZ, Valdez H, von Schack D, O'Neil SP, Reddy PS, Tatulych S; A3921147 Study Investigators.

J Allergy Clin Immunol. 2016 Apr;137(4):1079-90. doi: 10.1016/j.jaci.2015.12.1318.

6.

Methotrexate improves pro- and anti-atherogenic genomic expression in psoriatic skin.

Goldminz AM, Suárez-Fariñas M, Wang AC, Dumont N, Krueger JG, Gottlieb AB.

J Dermatol Sci. 2016 Jun;82(3):207-9. doi: 10.1016/j.jdermsci.2016.03.007. Epub 2016 Mar 9. No abstract available.

PMID:
27005302
7.

A mild topical steroid leads to progressive anti-inflammatory effects in the skin of patients with moderate-to-severe atopic dermatitis.

Brunner PM, Khattri S, Garcet S, Finney R, Oliva M, Dutt R, Fuentes-Duculan J, Zheng X, Li X, Bonifacio KM, Kunjravia N, Coats I, Cueto I, Gilleaudeau P, Sullivan-Whalen M, Suárez-Fariñas M, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2016 Feb 29. pii: S0091-6749(16)00136-6. doi: 10.1016/j.jaci.2015.12.1323. [Epub ahead of print]

PMID:
26948076
8.

Molecular and Cellular Profiling of Scalp Psoriasis Reveals Differences and Similarities Compared to Skin Psoriasis.

Ruano J, Suárez-Fariñas M, Shemer A, Oliva M, Guttman-Yassky E, Krueger JG.

PLoS One. 2016 Feb 5;11(2):e0148450. doi: 10.1371/journal.pone.0148450. eCollection 2016.

9.

Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes but Different Regulatory Gene Sets.

Kim J, Oh CH, Jeon J, Baek Y, Ahn J, Kim DJ, Lee HS, Correa da Rosa J, Suárez-Fariñas M, Lowes MA, Krueger JG.

J Invest Dermatol. 2016 Jan;136(1):161-72. doi: 10.1038/JID.2015.378.

PMID:
26763436
10.

The tryptophan metabolism enzyme L-kynureninase is a novel inflammatory factor in psoriasis and other inflammatory diseases.

Harden JL, Lewis SM, Lish SR, Suárez-Fariñas M, Gareau D, Lentini T, Johnson-Huang LM, Krueger JG, Lowes MA.

J Allergy Clin Immunol. 2016 Jun;137(6):1830-40. doi: 10.1016/j.jaci.2015.09.055. Epub 2015 Dec 22.

PMID:
26725996
11.

Biomarkers of alopecia areata disease activity and response to corticosteroid treatment.

Fuentes-Duculan J, Gulati N, Bonifacio KM, Kunjravia N, Zheng X, Suárez-Fariñas M, Shemer A, Guttman-Yassky E, Krueger JG.

Exp Dermatol. 2016 Apr;25(4):282-6. doi: 10.1111/exd.12918. Epub 2016 Mar 3.

PMID:
26661294
12.

Extensive alopecia areata is reversed by IL-12/IL-23p40 cytokine antagonism.

Guttman-Yassky E, Ungar B, Noda S, Suprun M, Shroff A, Dutt R, Khattri S, Min M, Mansouri Y, Zheng X, Estrada YD, Singer GK, Suarez-Farinas M, Krueger JG, Lebwohl MG.

J Allergy Clin Immunol. 2016 Jan;137(1):301-4. doi: 10.1016/j.jaci.2015.11.001. Epub 2015 Nov 20. No abstract available.

PMID:
26607705
13.

A Randomized, Placebo-Controlled Study of SRT2104, a SIRT1 Activator, in Patients with Moderate to Severe Psoriasis.

Krueger JG, Suárez-Fariñas M, Cueto I, Khacherian A, Matheson R, Parish LC, Leonardi C, Shortino D, Gupta A, Haddad J, Vlasuk GP, Jacobson EW.

PLoS One. 2015 Nov 10;10(11):e0142081. doi: 10.1371/journal.pone.0142081. eCollection 2015.

14.

Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways.

Ewald DA, Malajian D, Krueger JG, Workman CT, Wang T, Tian S, Litman T, Guttman-Yassky E, Suárez-Fariñas M.

BMC Med Genomics. 2015 Oct 12;8:60. doi: 10.1186/s12920-015-0133-x.

15.

Petrolatum: Barrier repair and antimicrobial responses underlying this "inert" moisturizer.

Czarnowicki T, Malajian D, Khattri S, Correa da Rosa J, Dutt R, Finney R, Dhingra N, Xiangyu P, Xu H, Estrada YD, Zheng X, Gilleaudeau P, Sullivan-Whalen M, Suaréz-Fariñas M, Shemer A, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2016 Apr;137(4):1091-1102.e7. doi: 10.1016/j.jaci.2015.08.013. Epub 2015 Oct 1.

PMID:
26431582
16.

The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization.

Noda S, Suárez-Fariñas M, Ungar B, Kim SJ, de Guzman Strong C, Xu H, Peng X, Estrada YD, Nakajima S, Honda T, Shin JU, Lee H, Krueger JG, Lee KH, Kabashima K, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1254-64. doi: 10.1016/j.jaci.2015.08.015. Epub 2015 Oct 1.

PMID:
26428954
17.

Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.

Suárez-Fariñas M, Ungar B, Noda S, Shroff A, Mansouri Y, Fuentes-Duculan J, Czernik A, Zheng X, Estrada YD, Xu H, Peng X, Shemer A, Krueger JG, Lebwohl MG, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24.

PMID:
26316095
18.

Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.

Goldstein J, Roth E, Roberts N, Zwick R, Lin S, Fletcher S, Tadeu A, Wu C, Beck A, Zeiss C, Suárez-Fariñas M, Horsley V.

Mol Biol Cell. 2015 Oct 15;26(20):3606-14. doi: 10.1091/mbc.E15-05-0282. Epub 2015 Aug 26.

19.

Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)(+) TH2/TH1 cell imbalance, whereas adults acquire CLA(+) TH22/TC22 cell subsets.

Czarnowicki T, Esaki H, Gonzalez J, Malajian D, Shemer A, Noda S, Talasila S, Berry A, Gray J, Becker L, Estrada Y, Xu H, Zheng X, Suárez-Fariñas M, Krueger JG, Paller AS, Guttman-Yassky E.

J Allergy Clin Immunol. 2015 Oct;136(4):941-951.e3. doi: 10.1016/j.jaci.2015.05.049. Epub 2015 Aug 1.

PMID:
26242300
20.

Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions.

Gulati N, Suárez-Fariñas M, Correa da Rosa J, Krueger JG.

F1000Res. 2015 Jun 11;4:149. doi: 10.12688/f1000research.6581.1. eCollection 2015.

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