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Results: 1 to 20 of 199

1.

A comprehensive evaluation of rodent malaria parasite genomes and gene expression.

Otto TD, Böhme U, Jackson AP, Hunt M, Franke-Fayard B, Hoeijmakers WA, Religa AA, Robertson L, Sanders M, Ogun SA, Cunningham D, Erhart A, Billker O, Khan SM, Stunnenberg HG, Langhorne J, Holder AA, Waters AP, Newbold CI, Pain A, Berriman M, Janse CJ.

BMC Biol. 2014 Oct 30;12(1):86. [Epub ahead of print]

PMID:
25359557
[PubMed - as supplied by publisher]
Free Article
2.

Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity.

Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, Cheng SC, Ratter J, Berentsen K, van der Ent MA, Sharifi N, Janssen-Megens EM, Ter Huurne M, Mandoli A, van Schaik T, Ng A, Burden F, Downes K, Frontini M, Kumar V, Giamarellos-Bourboulis EJ, Ouwehand WH, van der Meer JW, Joosten LA, Wijmenga C, Martens JH, Xavier RJ, Logie C, Netea MG, Stunnenberg HG.

Science. 2014 Sep 26;345(6204):1251086. doi: 10.1126/science.1251086.

PMID:
25258085
[PubMed - indexed for MEDLINE]
3.

Transcriptional diversity during lineage commitment of human blood progenitors.

Chen L, Kostadima M, Martens JH, Canu G, Garcia SP, Turro E, Downes K, Macaulay IC, Bielczyk-Maczynska E, Coe S, Farrow S, Poudel P, Burden F, Jansen SB, Astle WJ, Attwood A, Bariana T, de Bono B, Breschi A, Chambers JC; BRIDGE Consortium, Choudry FA, Clarke L, Coupland P, van der Ent M, Erber WN, Jansen JH, Favier R, Fenech ME, Foad N, Freson K, van Geet C, Gomez K, Guigo R, Hampshire D, Kelly AM, Kerstens HH, Kooner JS, Laffan M, Lentaigne C, Labalette C, Martin T, Meacham S, Mumford A, Nürnberg S, Palumbo E, van der Reijden BA, Richardson D, Sammut SJ, Slodkowicz G, Tamuri AU, Vasquez L, Voss K, Watt S, Westbury S, Flicek P, Loos R, Goldman N, Bertone P, Read RJ, Richardson S, Cvejic A, Soranzo N, Ouwehand WH, Stunnenberg HG, Frontini M, Rendon A.

Science. 2014 Sep 26;345(6204):1251033. doi: 10.1126/science.1251033.

PMID:
25258084
[PubMed - indexed for MEDLINE]
4.

mTOR- and HIF-1α-mediated aerobic glycolysis as metabolic basis for trained immunity.

Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG.

Science. 2014 Sep 26;345(6204):1250684. doi: 10.1126/science.1250684.

PMID:
25258083
[PubMed - indexed for MEDLINE]
5.

Analysis of chromatin-nuclear receptor interactions by laser-chromatin immunoprecipitation.

Benedetti R, Conte M, Carafa V, Della Ventura B, Altucci C, Velotta R, Stunnenberg HG, Altucci L, Nebbioso A.

Methods Mol Biol. 2014;1204:25-34. doi: 10.1007/978-1-4939-1346-6_3.

PMID:
25182758
[PubMed - in process]
6.

A polymorphic enhancer near GREM1 influences bowel cancer risk through differential CDX2 and TCF7L2 binding.

Lewis A, Freeman-Mills L, de la Calle-Mustienes E, Giráldez-Pérez RM, Davis H, Jaeger E, Becker M, Hubner NC, Nguyen LN, Zeron-Medina J, Bond G, Stunnenberg HG, Carvajal JJ, Gomez-Skarmeta JL, Leedham S, Tomlinson I.

Cell Rep. 2014 Aug 21;8(4):983-90. doi: 10.1016/j.celrep.2014.07.020. Epub 2014 Aug 14.

PMID:
25131200
[PubMed - in process]
Free Article
7.

Regulation of DNA methylation patterns by CK2-mediated phosphorylation of Dnmt3a.

Deplus R, Blanchon L, Rajavelu A, Boukaba A, Defrance M, Luciani J, Rothé F, Dedeurwaerder S, Denis H, Brinkman AB, Simmer F, Müller F, Bertin B, Berdasco M, Putmans P, Calonne E, Litchfield DW, de Launoit Y, Jurkowski TP, Stunnenberg HG, Bock C, Sotiriou C, Fraga MF, Esteller M, Jeltsch A, Fuks F.

Cell Rep. 2014 Aug 7;8(3):743-53. doi: 10.1016/j.celrep.2014.06.048. Epub 2014 Jul 24.

PMID:
25066127
[PubMed - in process]
Free Article
8.

Relationship between genome and epigenome--challenges and requirements for future research.

Almouzni G, Altucci L, Amati B, Ashley N, Baulcombe D, Beaujean N, Bock C, Bongcam-Rudloff E, Bousquet J, Braun S, Bressac-de Paillerets B, Bussemakers M, Clarke L, Conesa A, Estivill X, Fazeli A, Grgurević N, Gut I, Heijmans BT, Hermouet S, Houwing-Duistermaat J, Iacobucci I, Ilaš J, Kandimalla R, Krauss-Etschmann S, Lasko P, Lehmann S, Lindroth A, Majdič G, Marcotte E, Martinelli G, Martinet N, Meyer E, Miceli C, Mills K, Moreno-Villanueva M, Morvan G, Nickel D, Niesler B, Nowacki M, Nowak J, Ossowski S, Pelizzola M, Pochet R, Potočnik U, Radwanska M, Raes J, Rattray M, Robinson MD, Roelen B, Sauer S, Schinzer D, Slagboom E, Spector T, Stunnenberg HG, Tiligada E, Torres-Padilla ME, Tsonaka R, Van Soom A, Vidaković M, Widschwendter M.

BMC Genomics. 2014 Jun 18;15:487. doi: 10.1186/1471-2164-15-487.

PMID:
24942464
[PubMed - in process]
Free PMC Article
9.

Genome-wide binding of MBD2 reveals strong preference for highly methylated loci.

Menafra R, Brinkman AB, Matarese F, Franci G, Bartels SJ, Nguyen L, Shimbo T, Wade PA, Hubner NC, Stunnenberg HG.

PLoS One. 2014 Jun 13;9(6):e99603. doi: 10.1371/journal.pone.0099603. eCollection 2014.

PMID:
24927503
[PubMed - in process]
Free PMC Article
10.

Inference of RNA polymerase II transcription dynamics from chromatin immunoprecipitation time course data.

wa Maina C, Honkela A, Matarese F, Grote K, Stunnenberg HG, Reid G, Lawrence ND, Rattray M.

PLoS Comput Biol. 2014 May 15;10(5):e1003598. doi: 10.1371/journal.pcbi.1003598. eCollection 2014 May.

PMID:
24830797
[PubMed - in process]
Free PMC Article
11.

Dual promoter usage as regulatory mechanism of let-7c expression in leukemic and solid tumors.

Pelosi A, Careccia S, Sagrestani G, Nanni S, Manni I, Schinzari V, Martens JH, Farsetti A, Stunnenberg HG, Gentileschi MP, Del Bufalo D, De Maria R, Piaggio G, Rizzo MG.

Mol Cancer Res. 2014 Jun;12(6):878-89. doi: 10.1158/1541-7786.MCR-13-0410. Epub 2014 Mar 17.

PMID:
24637061
[PubMed - in process]
12.

Context-selective death of acute myeloid leukemia cells triggered by the novel hybrid retinoid-HDAC inhibitor MC2392.

De Bellis F, Carafa V, Conte M, Rotili D, Petraglia F, Matarese F, Françoijs KJ, Ablain J, Valente S, Castellano R, Goubard A, Collette Y, Mandoli A, Martens JH, de Thé H, Nebbioso A, Mai A, Stunnenberg HG, Altucci L.

Cancer Res. 2014 Apr 15;74(8):2328-39. doi: 10.1158/0008-5472.CAN-13-2568. Epub 2014 Feb 24.

PMID:
24566867
[PubMed - indexed for MEDLINE]
13.

Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF.

Development. 2014 Feb;141(3):526-37. doi: 10.1242/dev.102681. Epub 2014 Jan 14.

PMID:
24423662
[PubMed - indexed for MEDLINE]
Free Article
14.

The class I-specific HDAC inhibitor MS-275 modulates the differentiation potential of mouse embryonic stem cells.

Franci G, Casalino L, Petraglia F, Miceli M, Menafra R, Radic B, Tarallo V, Vitale M, Scarfò M, Pocsfalvi G, Baldi A, Ambrosino C, Zambrano N, Patriarca E, De Falco S, Minchiotti G, Stunnenberg HG, Altucci L.

Biol Open. 2013 Aug 22;2(10):1070-7. doi: 10.1242/bio.20135587. eCollection 2013.

PMID:
24167717
[PubMed]
Free PMC Article
15.

Genomics meets proteomics: identifying the culprits in disease.

Stunnenberg HG, Hubner NC.

Hum Genet. 2014 Jun;133(6):689-700. doi: 10.1007/s00439-013-1376-2. Epub 2013 Oct 18. Review.

PMID:
24135908
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transcription regulation and chromatin structure in the pluripotent ground state.

Marks H, Stunnenberg HG.

Biochim Biophys Acta. 2014 Mar;1839(3):129-37. doi: 10.1016/j.bbagrm.2013.09.005. Epub 2013 Oct 2. Review.

PMID:
24096207
[PubMed - indexed for MEDLINE]
17.

BLUEPRINT: mapping human blood cell epigenomes.

Martens JH, Stunnenberg HG.

Haematologica. 2013 Oct;98(10):1487-9. doi: 10.3324/haematol.2013.094243. No abstract available.

PMID:
24091925
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.

Neri F, Krepelova A, Incarnato D, Maldotti M, Parlato C, Galvagni F, Matarese F, Stunnenberg HG, Oliviero S.

Cell. 2013 Sep 26;155(1):121-34. doi: 10.1016/j.cell.2013.08.056.

PMID:
24074865
[PubMed - indexed for MEDLINE]
Free Article
19.

CBFB-MYH11/RUNX1 together with a compendium of hematopoietic regulators, chromatin modifiers and basal transcription factors occupies self-renewal genes in inv(16) acute myeloid leukemia.

Mandoli A, Singh AA, Jansen PW, Wierenga AT, Riahi H, Franci G, Prange K, Saeed S, Vellenga E, Vermeulen M, Stunnenberg HG, Martens JH.

Leukemia. 2014 Apr;28(4):770-8. doi: 10.1038/leu.2013.257. Epub 2013 Sep 4.

PMID:
24002588
[PubMed - indexed for MEDLINE]
20.

Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner.

Gupta VK, Scheunemann L, Eisenberg T, Mertel S, Bhukel A, Koemans TS, Kramer JM, Liu KS, Schroeder S, Stunnenberg HG, Sinner F, Magnes C, Pieber TR, Dipt S, Fiala A, Schenck A, Schwaerzel M, Madeo F, Sigrist SJ.

Nat Neurosci. 2013 Oct;16(10):1453-60. doi: 10.1038/nn.3512. Epub 2013 Sep 1.

PMID:
23995066
[PubMed - indexed for MEDLINE]

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