Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 35

1.

Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines.

Vartanian S, Bentley C, Brauer MJ, Li L, Shirasawa S, Sasazuki T, Kim JS, Haverty P, Stawiski E, Modrusan Z, Waldman T, Stokoe D.

J Biol Chem. 2013 Jan 25;288(4):2403-13. doi: 10.1074/jbc.M112.394130. Epub 2012 Nov 27.

PMID:
23188824
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Disruption of PH-kinase domain interactions leads to oncogenic activation of AKT in human cancers.

Parikh C, Janakiraman V, Wu WI, Foo CK, Kljavin NM, Chaudhuri S, Stawiski E, Lee B, Lin J, Li H, Lorenzo MN, Yuan W, Guillory J, Jackson M, Rondon J, Franke Y, Bowman KK, Sagolla M, Stinson J, Wu TD, Wu J, Stokoe D, Stern HM, Brandhuber BJ, Lin K, Skelton NJ, Seshagiri S.

Proc Natl Acad Sci U S A. 2012 Nov 20;109(47):19368-73. doi: 10.1073/pnas.1204384109. Epub 2012 Nov 7.

PMID:
23134728
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

Liu J, Lee W, Jiang Z, Chen Z, Jhunjhunwala S, Haverty PM, Gnad F, Guan Y, Gilbert HN, Stinson J, Klijn C, Guillory J, Bhatt D, Vartanian S, Walter K, Chan J, Holcomb T, Dijkgraaf P, Johnson S, Koeman J, Minna JD, Gazdar AF, Stern HM, Hoeflich KP, Wu TD, Settleman J, de Sauvage FJ, Gentleman RC, Neve RM, Stokoe D, Modrusan Z, Seshagiri S, Shames DS, Zhang Z.

Genome Res. 2012 Dec;22(12):2315-27. doi: 10.1101/gr.140988.112. Epub 2012 Oct 2.

PMID:
23033341
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity.

Maurer T, Garrenton LS, Oh A, Pitts K, Anderson DJ, Skelton NJ, Fauber BP, Pan B, Malek S, Stokoe D, Ludlam MJ, Bowman KK, Wu J, Giannetti AM, Starovasnik MA, Mellman I, Jackson PK, Rudolph J, Wang W, Fang G.

Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5299-304. doi: 10.1073/pnas.1116510109. Epub 2012 Mar 19.

PMID:
22431598
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression.

Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, Haas-Kogan DA, McBride S, Marsit CJ, Christensen BC, Nelson HH, Stokoe D, Wiemels JL, Chang SM, Prados MD, Tihan T, Vandenberg SR, Kelsey KT, Berger MS, Wiencke JK.

Neuro Oncol. 2011 Mar;13(3):280-9. doi: 10.1093/neuonc/noq190.

PMID:
21339190
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Zinc finger nucleases as tools to understand and treat human diseases.

Davis D, Stokoe D.

BMC Med. 2010 Jul 1;8:42. doi: 10.1186/1741-7015-8-42. Review.

PMID:
20594338
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Converting cancer mutations into therapeutic opportunities.

O'Brien T, Stokoe D.

EMBO Mol Med. 2009 Sep;1(6-7):297-9. doi: 10.1002/emmm.200900044.

PMID:
20049732
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Activation of PI3K/mTOR pathway occurs in most adult low-grade gliomas and predicts patient survival.

McBride SM, Perez DA, Polley MY, Vandenberg SR, Smith JS, Zheng S, Lamborn KR, Wiencke JK, Chang SM, Prados MD, Berger MS, Stokoe D, Haas-Kogan DA.

J Neurooncol. 2010 Mar;97(1):33-40. doi: 10.1007/s11060-009-0004-4. Epub 2009 Aug 25.

PMID:
19705067
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

EGFR signals to mTOR through PKC and independently of Akt in glioma.

Fan QW, Cheng C, Knight ZA, Haas-Kogan D, Stokoe D, James CD, McCormick F, Shokat KM, Weiss WA.

Sci Signal. 2009 Jan 27;2(55):ra4. doi: 10.1126/scisignal.2000014. Erratum in: Sci Signal. 2009;2(60):er4.

PMID:
19176518
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Phase II study of erlotinib plus temozolomide during and after radiation therapy in patients with newly diagnosed glioblastoma multiforme or gliosarcoma.

Prados MD, Chang SM, Butowski N, DeBoer R, Parvataneni R, Carliner H, Kabuubi P, Ayers-Ringler J, Rabbitt J, Page M, Fedoroff A, Sneed PK, Berger MS, McDermott MW, Parsa AT, Vandenberg S, James CD, Lamborn KR, Stokoe D, Haas-Kogan DA.

J Clin Oncol. 2009 Feb 1;27(4):579-84. doi: 10.1200/JCO.2008.18.9639. Epub 2008 Dec 15.

PMID:
19075262
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Signal transduction molecules in gliomas of all grades.

Ermoian RP, Kaprealian T, Lamborn KR, Yang X, Jelluma N, Arvold ND, Zeidman R, Berger MS, Stokoe D, Haas-Kogan DA.

J Neurooncol. 2009 Jan;91(1):19-26. doi: 10.1007/s11060-008-9683-5. Epub 2008 Sep 1.

PMID:
18759130
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Cell cycle-dependent phosphorylation of human CDC5 regulates RNA processing.

Gräub R, Lancero H, Pedersen A, Chu M, Padmanabhan K, Xu XQ, Spitz P, Chalkley R, Burlingame AL, Stokoe D, Bernstein HS.

Cell Cycle. 2008 Jun 15;7(12):1795-803. Epub 2008 Jun 25.

PMID:
18583928
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Analysis of 3-phosphoinositide-dependent kinase-1 signaling and function in ES cells.

Tamgüney T, Zhang C, Fiedler D, Shokat K, Stokoe D.

Exp Cell Res. 2008 Jul 1;314(11-12):2299-312. doi: 10.1016/j.yexcr.2008.04.006. Epub 2008 Apr 23.

PMID:
18514190
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition.

Torbett NE, Luna-Moran A, Knight ZA, Houk A, Moasser M, Weiss W, Shokat KM, Stokoe D.

Biochem J. 2008 Oct 1;415(1):97-110. doi: 10.1042/BJ20080639.

PMID:
18498248
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Tuberous sclerosis complex proteins 1 and 2 control serum-dependent translation in a TOP-dependent and -independent manner.

Bilanges B, Argonza-Barrett R, Kolesnichenko M, Skinner C, Nair M, Chen M, Stokoe D.

Mol Cell Biol. 2007 Aug;27(16):5746-64. Epub 2007 Jun 11.

PMID:
17562867
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma.

Wiencke JK, Zheng S, Jelluma N, Tihan T, Vandenberg S, Tamgüney T, Baumber R, Parsons R, Lamborn KR, Berger MS, Wrensch MR, Haas-Kogan DA, Stokoe D.

Neuro Oncol. 2007 Jul;9(3):271-9. Epub 2007 May 15.

PMID:
17504928
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

mTOR-independent translational control of the extrinsic cell death pathway by RalA.

Panner A, Nakamura JL, Parsa AT, Rodriguez-Viciana P, Berger MS, Stokoe D, Pieper RO.

Mol Cell Biol. 2006 Oct;26(20):7345-57. Epub 2006 Aug 7.

PMID:
16894031
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.

Fan QW, Knight ZA, Goldenberg DD, Yu W, Mostov KE, Stokoe D, Shokat KM, Weiss WA.

Cancer Cell. 2006 May;9(5):341-9.

PMID:
16697955
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.

Knight ZA, Gonzalez B, Feldman ME, Zunder ER, Goldenberg DD, Williams O, Loewith R, Stokoe D, Balla A, Toth B, Balla T, Weiss WA, Williams RL, Shokat KM.

Cell. 2006 May 19;125(4):733-47. Epub 2006 Apr 27.

PMID:
16647110
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Translational deregulation in PDK-1-/- embryonic stem cells.

Tominaga Y, Tamgüney T, Kolesnichenko M, Bilanges B, Stokoe D.

Mol Cell Biol. 2005 Oct;25(19):8465-75.

PMID:
16166629
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk