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Results: 1 to 20 of 77

1.

Ruthenium complexes as inhibitors of the aldo-keto reductases AKR1C1-1C3.

Traven K, Sinreih M, Stojan J, Seršen S, Kljun J, Bezenšek J, Stanovnik B, Turel I, Rižner TL.

Chem Biol Interact. 2014 Nov 18. pii: S0009-2797(14)00354-8. doi: 10.1016/j.cbi.2014.11.005. [Epub ahead of print]

PMID:
25446855
[PubMed - as supplied by publisher]
2.

Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.

Brus B, Košak U, Turk S, Pišlar A, Coquelle N, Kos J, Stojan J, Colletier JP, Gobec S.

J Med Chem. 2014 Oct 9;57(19):8167-79. doi: 10.1021/jm501195e. Epub 2014 Sep 29.

PMID:
25226236
[PubMed - indexed for MEDLINE]
3.

Cytochrome P450 monooxygenase CYP53 family in fungi: comparative structural and evolutionary analysis and its role as a common alternative anti-fungal drug target.

Jawallapersand P, Mashele SS, Kovačič L, Stojan J, Komel R, Pakala SB, Kraševec N, Syed K.

PLoS One. 2014 Sep 15;9(9):e107209. doi: 10.1371/journal.pone.0107209. eCollection 2014.

PMID:
25222113
[PubMed - in process]
Free PMC Article
4.

Exploring the aryl esterase catalysis of paraoxonase-1 through solvent kinetic isotope effects and phosphonate-based isosteric analogues of the tetrahedral reaction intermediate.

Bavec A, Knez D, Makovec T, Stojan J, Gobec S, Goličnik M.

Biochimie. 2014 Nov;106:184-6. doi: 10.1016/j.biochi.2014.08.011. Epub 2014 Aug 30.

PMID:
25180809
[PubMed - in process]
5.

Medical school handoff education improves postgraduate trainee performance and confidence.

Stojan JN, Schiller JH, Mullan P, Fitzgerald JT, Christner J, Ross PT, Middlemas S, Haftel H, Stansfield RB, Lypson ML.

Med Teach. 2014 Aug 26:1-8. [Epub ahead of print]

PMID:
25155969
[PubMed - as supplied by publisher]
6.

Intestinal cell barrier function in vitro is severely compromised by keratin 8 and 18 mutations identified in patients with inflammatory bowel disease.

Zupancic T, Stojan J, Lane EB, Komel R, Bedina-Zavec A, Liovic M.

PLoS One. 2014 Jun 10;9(6):e99398. doi: 10.1371/journal.pone.0099398. eCollection 2014.

PMID:
24915158
[PubMed - in process]
Free PMC Article
7.

Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53).

Korošec B, Sova M, Turk S, Kraševec N, Novak M, Lah L, Stojan J, Podobnik B, Berne S, Zupanec N, Bunc M, Gobec S, Komel R.

J Appl Microbiol. 2014 Apr;116(4):955-66. doi: 10.1111/jam.12417. Epub 2014 Jan 2.

PMID:
24314266
[PubMed - indexed for MEDLINE]
8.

Training may impact shift work mentality in students.

Stojan JN, Schiller JH, Fitzgerald JT, Lypson ML.

Med Educ. 2013 Nov;47(11):1126-7. doi: 10.1111/medu.12321. No abstract available.

PMID:
24117568
[PubMed - indexed for MEDLINE]
9.

Discovery of the first inhibitors of bacterial enzyme D-aspartate ligase from Enterococcus faecium (Aslfm).

Škedelj V, Perdih A, Brvar M, Kroflič A, Dubbée V, Savage V, O'Neill AJ, Solmajer T, Bešter-Rogač M, Blanot D, Hugonnet JE, Magnet S, Arthur M, Mainardi JL, Stojan J, Zega A.

Eur J Med Chem. 2013 Sep;67:208-20. doi: 10.1016/j.ejmech.2013.06.017. Epub 2013 Jun 28.

PMID:
23867605
[PubMed - indexed for MEDLINE]
10.

The significance of low substrate concentration measurements for mechanistic interpretation in cholinesterases.

Stojan J.

Chem Biol Interact. 2013 Mar 25;203(1):44-50. doi: 10.1016/j.cbi.2012.12.005. Epub 2012 Dec 29.

PMID:
23279886
[PubMed - indexed for MEDLINE]
11.

Virtual screening yields inhibitors of novel antifungal drug target, benzoate 4-monooxygenase.

Berne S, Podobnik B, Zupanec N, Novak M, Kraševec N, Turk S, Korošec B, Lah L, Šuligoj E, Stojan J, Gobec S, Komel R.

J Chem Inf Model. 2012 Nov 26;52(11):3053-63. doi: 10.1021/ci3004418. Epub 2012 Nov 8.

PMID:
23092521
[PubMed - indexed for MEDLINE]
12.

Kinetics of Torpedo californica acetylcholinesterase inhibition by bisnorcymserine and crystal structure of the complex with its leaving group.

Bartolucci C, Stojan J, Yu QS, Greig NH, Lamba D.

Biochem J. 2012 Jun 1;444(2):269-77. doi: 10.1042/BJ20111675.

PMID:
22390827
[PubMed - indexed for MEDLINE]
Free Article
13.

Insights into subtle conformational differences in the substrate-binding loop of fungal 17β-hydroxysteroid dehydrogenase: a combined structural and kinetic approach.

Cassetta A, Krastanova I, Kristan K, Brunskole Švegelj M, Lamba D, Lanišnik Rižner T, Stojan J.

Biochem J. 2012 Jan 1;441(1):151-60. doi: 10.1042/BJ20110567.

PMID:
21929506
[PubMed - indexed for MEDLINE]
Free Article
14.

ENZO: a web tool for derivation and evaluation of kinetic models of enzyme catalyzed reactions.

Bevc S, Konc J, Stojan J, Hodošček M, Penca M, Praprotnik M, Janežič D.

PLoS One. 2011;6(7):e22265. doi: 10.1371/journal.pone.0022265. Epub 2011 Jul 19.

PMID:
21818304
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The versatility of the fungal cytochrome P450 monooxygenase system is instrumental in xenobiotic detoxification.

Lah L, Podobnik B, Novak M, Korošec B, Berne S, Vogelsang M, Kraševec N, Zupanec N, Stojan J, Bohlmann J, Komel R.

Mol Microbiol. 2011 Sep;81(5):1374-89. doi: 10.1111/j.1365-2958.2011.07772.x. Epub 2011 Aug 2.

PMID:
21810122
[PubMed - indexed for MEDLINE]
16.

Mechanism of stereoselective interaction between butyrylcholinesterase and ethopropazine enantiomers.

Sinko G, Kovarik Z, Reiner E, Simeon-Rudolf V, Stojan J.

Biochimie. 2011 Oct;93(10):1797-807. doi: 10.1016/j.biochi.2011.06.023. Epub 2011 Jun 29.

PMID:
21740955
[PubMed - indexed for MEDLINE]
17.

Novel inhibitors of trihydroxynaphthalene reductase with antifungal activity identified by ligand-based and structure-based virtual screening.

Brunskole Svegelj M, Turk S, Brus B, Lanisnik Rizner T, Stojan J, Gobec S.

J Chem Inf Model. 2011 Jul 25;51(7):1716-24. doi: 10.1021/ci2001499. Epub 2011 Jun 21.

PMID:
21667970
[PubMed - indexed for MEDLINE]
18.

The role of Ala231 and Trp227 in the substrate specificities of fungal 17β-hydroxysteroid dehydrogenase and trihydroxynaphthalene reductase: Steroids versus smaller substrates.

Svegelj MB, Stojan J, Rižner TL.

J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):92-8. doi: 10.1016/j.jsbmb.2011.03.019. Epub 2011 Mar 23.

PMID:
21439381
[PubMed - indexed for MEDLINE]
19.

Non-productive binding of butyryl(thio)choline in the active site of vertebrate acetylcholinesterase.

Stojan J.

Chem Biol Interact. 2010 Sep 6;187(1-3):128-34. doi: 10.1016/j.cbi.2010.05.001. Epub 2010 May 7.

PMID:
20452336
[PubMed - indexed for MEDLINE]
20.

Localization and properties of cholinesterases in the common prawn (Palaemon serratus): A kinetic-histochemical study.

Frasco MF, Erzen I, Stojan J, Guilhermino L.

Biol Bull. 2010 Feb;218(1):1-5.

PMID:
20203248
[PubMed - indexed for MEDLINE]
Free Article

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