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Results: 11


Model based engineering of Pichia pastoris central metabolism enhances recombinant protein production.

Nocon J, Steiger MG, Pfeffer M, Sohn SB, Kim TY, Maurer M, Rußmayer H, Pflügl S, Ask M, Haberhauer-Troyer C, Ortmayr K, Hann S, Koellensperger G, Gasser B, Lee SY, Mattanovich D.

Metab Eng. 2014 Jul;24:129-38. doi: 10.1016/j.ymben.2014.05.011. Epub 2014 May 20.


In Pichia pastoris, growth rate regulates protein synthesis and secretion, mating and stress response.

Rebnegger C, Graf AB, Valli M, Steiger MG, Gasser B, Maurer M, Mattanovich D.

Biotechnol J. 2014 Apr;9(4):511-25. doi: 10.1002/biot.201300334. Epub 2014 Jan 14.


Targeting enzymes to the right compartment: metabolic engineering for itaconic acid production by Aspergillus niger.

Blumhoff ML, Steiger MG, Mattanovich D, Sauer M.

Metab Eng. 2013 Sep;19:26-32. doi: 10.1016/j.ymben.2013.05.003. Epub 2013 May 29.


Biochemistry of microbial itaconic acid production.

Steiger MG, Blumhoff ML, Mattanovich D, Sauer M.

Front Microbiol. 2013 Feb 14;4:23. doi: 10.3389/fmicb.2013.00023. eCollection 2013.


U13C cell extract of Pichia pastoris--a powerful tool for evaluation of sample preparation in metabolomics.

Neubauer S, Haberhauer-Troyer C, Klavins K, Russmayer H, Steiger MG, Gasser B, Sauer M, Mattanovich D, Hann S, Koellensperger G.

J Sep Sci. 2012 Nov;35(22):3091-105. doi: 10.1002/jssc.201200447. Epub 2012 Oct 22.


Six novel constitutive promoters for metabolic engineering of Aspergillus niger.

Blumhoff M, Steiger MG, Marx H, Mattanovich D, Sauer M.

Appl Microbiol Biotechnol. 2013 Jan;97(1):259-67. doi: 10.1007/s00253-012-4207-9. Epub 2012 Jun 16.


Synthesis of an antiviral drug precursor from chitin using a saprophyte as a whole-cell catalyst.

Steiger MG, Mach-Aigner AR, Gorsche R, Rosenberg EE, Mihovilovic MD, Mach RL.

Microb Cell Fact. 2011 Dec 5;10:102. doi: 10.1186/1475-2859-10-102.


Transformation system for Hypocrea jecorina (Trichoderma reesei) that favors homologous integration and employs reusable bidirectionally selectable markers.

Steiger MG, Vitikainen M, Uskonen P, Brunner K, Adam G, Pakula T, Penttilä M, Saloheimo M, Mach RL, Mach-Aigner AR.

Appl Environ Microbiol. 2011 Jan;77(1):114-21. doi: 10.1128/AEM.02100-10. Epub 2010 Nov 12.


An accurate normalization strategy for RT-qPCR in Hypocrea jecorina (Trichoderma reesei).

Steiger MG, Mach RL, Mach-Aigner AR.

J Biotechnol. 2010 Jan 1;145(1):30-7. doi: 10.1016/j.jbiotec.2009.10.012. Epub .


Transcriptional regulation of xyr1, encoding the main regulator of the xylanolytic and cellulolytic enzyme system in Hypocrea jecorina.

Mach-Aigner AR, Pucher ME, Steiger MG, Bauer GE, Preis SJ, Mach RL.

Appl Environ Microbiol. 2008 Nov;74(21):6554-62. doi: 10.1128/AEM.01143-08. Epub 2008 Sep 12.


Xyr1 receives the lactose induction signal and regulates lactose metabolism in Hypocrea jecorina.

Stricker AR, Steiger MG, Mach RL.

FEBS Lett. 2007 Aug 21;581(21):3915-20. Epub 2007 Jul 23.

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