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Page 1
Mirikizumab Regulates Genes Involved in Ulcerative Colitis Disease Activity and Anti-TNF Resistance: Results From a Phase 2 Study.
Clin Transl Gastroenterol. 2023 Jul 1;14(7):e00578. doi: 10.14309/ctg.0000000000000578.
Clin Transl Gastroenterol. 2023.
PMID: 36881820
Free PMC article.
Clinical Trial.
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance.
Aschenbrenner D, Quaranta M, Banerjee S, Ilott N, Jansen J, Steere B, Chen YH, Ho S, Cox K, Arancibia-Cárcamo CV, Coles M, Gaffney E, Travis SP, Denson L, Kugathasan S, Schmitz J, Powrie F, Sansom SN, Uhlig HH.
Aschenbrenner D, et al. Among authors: steere b.
Gut. 2021 Jun;70(6):1023-1036. doi: 10.1136/gutjnl-2020-321731. Epub 2020 Oct 9.
Gut. 2021.
PMID: 33037057
Free PMC article.
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Generation and Characterization of Mirikizumab, a Humanized Monoclonal Antibody Targeting the p19 Subunit of IL-23.
Steere B, Beidler C, Martin A, Bright S, Kikly K, Benschop RJ.
Steere B, et al.
J Pharmacol Exp Ther. 2023 Nov;387(2):180-187. doi: 10.1124/jpet.122.001512. Epub 2023 Sep 15.
J Pharmacol Exp Ther. 2023.
PMID: 37714687
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Mirikizumab-Induced Transcriptome Changes in Ulcerative Colitis Patient Biopsies at Week 12 Are Maintained Through Week 52.
Johnson T, Steere B, Zhang P, Zang Y, Higgs R, Milch C, Reinisch W, Panés J, Huang K, D'Haens G, Krishnan V.
Johnson T, et al. Among authors: steere b.
Clin Transl Gastroenterol. 2023 Nov 1;14(11):e00630. doi: 10.14309/ctg.0000000000000630.
Clin Transl Gastroenterol. 2023.
PMID: 37594044
Free PMC article.
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Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1.
Dumaual CM, Steere BA, Walls CD, Wang M, Zhang ZY, Randall SK.
Dumaual CM, et al. Among authors: steere ba.
PLoS One. 2013 Sep 3;8(9):e72977. doi: 10.1371/journal.pone.0072977. eCollection 2013.
PLoS One. 2013.
PMID: 24019887
Free PMC article.
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Prediction of in vivo clearance and associated variability of CYP2C19 substrates by genotypes in populations utilizing a pharmacogenetics-based mechanistic model.
Steere B, Baker JA, Hall SD, Guo Y.
Steere B, et al.
Drug Metab Dispos. 2015 Jun;43(6):870-83. doi: 10.1124/dmd.114.061523. Epub 2015 Apr 6.
Drug Metab Dispos. 2015.
PMID: 25845826
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