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2018 4
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Page 1
Cytotoxic Polyhydroxysteroidal Glycosides from Starfish Culcita novaeguineae.
Lu Y, Li H, Wang M, Liu Y, Feng Y, Liu K, Tang H. Lu Y, et al. Mar Drugs. 2018 Mar 13;16(3):92. doi: 10.3390/md16030092. Mar Drugs. 2018. PMID: 29534028 Free PMC article.
Four new polyhydroxysteroidal glycosides-culcinosides A-D (1, 2, 4, and 7)-along with three known compounds-echinasteroside C (3), linckoside F (5), and linckoside L3 (6)-were isolated from the ethanol extract of starfish Culcita novaeguineae collected from the Xisha Islan …
Four new polyhydroxysteroidal glycosides-culcinosides A-D (1, 2, 4, and 7)-along with three known compounds-echinasteroside C (3), linckosid …
Six New Polyhydroxysteroidal Glycosides, Anthenosides S1 - S6, from the Starfish Anthenea sibogae.
Kicha AA, Ha DT, Ivanchina NV, Malyarenko TV, Kalinovsky AI, Dmitrenok PS, Ermakova SP, Malyarenko OS, Hung NA, Thuy TTT, Long PQ. Kicha AA, et al. Chem Biodivers. 2018 Mar;15(3):e1700553. doi: 10.1002/cbdv.201700553. Epub 2018 Mar 2. Chem Biodivers. 2018. PMID: 29356326
All new compounds have a 5alpha-cholest-8(14)-ene-3alpha,6beta,7beta,16alpha-tetrahydroxysteroidal nucleus and differ from majority of starfish glycosides in positions of carbohydrate moieties at C(7) and C(16) (1 - 4, 6) or only at C(16) (5). The 4-O-methyl-beta-d-glucopy …
All new compounds have a 5alpha-cholest-8(14)-ene-3alpha,6beta,7beta,16alpha-tetrahydroxysteroidal nucleus and differ from majority of st …
Bioactive asterosaponins from the starfish Culcita novaeguineae.
Tang HF, Yi YH, Li L, Sun P, Zhang SQ, Zhao YP. Tang HF, et al. J Nat Prod. 2005 Mar;68(3):337-41. doi: 10.1021/np0401617. J Nat Prod. 2005. PMID: 15787432
Two new sulfated steroidal pentaglycosides (asterosaponins), novaeguinosides I (2) and II (3), along with the known regularoside B (1) were isolated from the starfish Culcita novaeguineae. Their structures were elucidated by extensive NMR techniques as well as chemical evi …
Two new sulfated steroidal pentaglycosides (asterosaponins), novaeguinosides I (2) and II (3), along with the known regularoside B (1) were …
Polar steroid derivatives from the Vietnamese starfish Astropecten polyacanthus.
Vien LT, Hanh TTH, Hong PT, Thanh NV, Huong TT, Cuong NX, Nam NH, Thung DC, Kiem PV, Minh CV. Vien LT, et al. Nat Prod Res. 2018 Jan;32(1):54-59. doi: 10.1080/14786419.2017.1329733. Epub 2017 May 16. Nat Prod Res. 2018. PMID: 28511566
Five polar steroid derivatives, including one new glycosylated polyhydroxysteroid namely polyacanthoside A (1), were isolated from the water-soluble materials from the MeOH extract of the Vietnamese starfish Astropecten polyacanthus using various chromatographic separation …
Five polar steroid derivatives, including one new glycosylated polyhydroxysteroid namely polyacanthoside A (1), were isolated from the water …
Cytotoxic sterols and saponins from the starfish Certonardoa semiregularis.
Wang W, Hong J, Lee CO, Im KS, Choi JS, Jung JH. Wang W, et al. J Nat Prod. 2004 Apr;67(4):584-91. doi: 10.1021/np030427u. J Nat Prod. 2004. PMID: 15104487
Eleven new polyhydroxysterols (1-11) and eight new saponins (12-19) were isolated from the brine shrimp active fraction of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical derivatization. ...
Eleven new polyhydroxysterols (1-11) and eight new saponins (12-19) were isolated from the brine shrimp active fraction of the starfish …
Polyhydroxysteroidal glycosides from the starfish Anthenea chinensis.
Ma N, Tang HF, Qiu F, Lin HW, Tian XR, Yao MN. Ma N, et al. J Nat Prod. 2010 Apr 23;73(4):590-7. doi: 10.1021/np9007188. J Nat Prod. 2010. PMID: 20184290
Ten new polyhydroxysteroidal glycosides, anthenosides B-K (2-11), were isolated from the ethanol extract of the starfish Anthenea chinensis. Their structures were elucidated by extensive spectroscopic studies and chemical evidence. ...
Ten new polyhydroxysteroidal glycosides, anthenosides B-K (2-11), were isolated from the ethanol extract of the starfish Anthenea chi …
Alkyl and alkoxyethyl antineoplastic phospholipids.
Koufaki M, Polychroniou V, Calogeropoulou T, Tsotinis A, Drees M, Fiebig HH, LeClerc S, Hendriks HR, Makriyannis A. Koufaki M, et al. J Med Chem. 1996 Jun 21;39(13):2609-14. doi: 10.1021/jm9509152. J Med Chem. 1996. PMID: 8691459
The cytotoxic activity of these compounds (9-19) was evaluated in vitro against a panel of six human tumor xenografts and in two biochemical, mechanism-based screens (cdc2 kinase and cdc25 phosphatase). Analogs 13, 14, 17, and 19 showed activity in the in vitro tests. ...I …
The cytotoxic activity of these compounds (9-19) was evaluated in vitro against a panel of six human tumor xenografts and in two biochemical …
Renal histology and MRI in a 25-year-old Japanese man with nephronophthisis 4
.
Takada D, Sekine A, Yabuuchi J, Kogure Y, Ueno T, Yamanouchi M, Sumida K, Suwabe T, Hayami N, Hoshino J, Takaichi K, Kinowaki K, Fujii T, Ohashi K, Mori T, Sohara E, Uchida S, Ubara Y. Takada D, et al. Clin Nephrol. 2018 Mar;89(3):223-228. doi: 10.5414/CN109175. Clin Nephrol. 2018. PMID: 29162218
Renal biopsy demonstrated interstitial fibrosis, especially at the corticomedullary junction. The residual tubular system showed starfish-like disruption. Tubules with cystic dilation were mainly the distal loop of Henle and the distal tubules since immunohistochemical sta …
Renal biopsy demonstrated interstitial fibrosis, especially at the corticomedullary junction. The residual tubular system showed starfish …
Bioactive sterols from the starfish Certonardoa semiregularis.
Wang W, Li F, Park Y, Hong J, Lee CO, Kong JY, Shin S, Im KS, Jung JH. Wang W, et al. J Nat Prod. 2003 Mar;66(3):384-91. doi: 10.1021/np020507i. J Nat Prod. 2003. PMID: 12662097
Thirteen new polyhydroxysterols (1-5, 7-12, 14, 15) and two known polyhydroxysterols (6, 13) were isolated from the brine shrimp active fraction of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical derivat …
Thirteen new polyhydroxysterols (1-5, 7-12, 14, 15) and two known polyhydroxysterols (6, 13) were isolated from the brine shrimp active frac …
Asterosaponins and glycosylated polyhydroxysteroids from the starfish Culcita novaeguineae and their cytotoxic activities.
Ngoan BT, Hanh TT, Vien le T, Diep CN, Thao NP, Thao do T, Thanh NV, Cuong NX, Nam NH, Thung do C, Kiem PV, Kim YH, Minh CV. Ngoan BT, et al. J Asian Nat Prod Res. 2015;17(10):1010-7. doi: 10.1080/10286020.2015.1041930. Epub 2015 May 22. J Asian Nat Prod Res. 2015. PMID: 26001122
Using combined chromatographic methods, two asterosaponins (compounds 1 and 2), including a new compound novaeguinoside E (compound 1), and six glycosylated polyhydroxysteroids (compounds 3-8) were isolated from a methanol extract of the starfish Culcita novaeguineae. Thei …
Using combined chromatographic methods, two asterosaponins (compounds 1 and 2), including a new compound novaeguinoside E (compound 1), and …
21 results