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Further characterisation of transmissible spongiform encephalopathy phenotypes after inoculation of cattle with two temporally separated sources of sheep scrapie from Great Britain.

Konold T, Nonno R, Spiropoulos J, Chaplin MJ, Stack MJ, Hawkins SA, Cawthraw S, Wilesmith JW, Wells GA, Agrimi U, Di Bari MA, Andréoletti O, Espinosa JC, Aguilar-Calvo P, Torres JM.

BMC Res Notes. 2015 Jul 24;8:312. doi: 10.1186/s13104-015-1260-3.


Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?

Simmons MM, Chaplin MJ, Vickery CM, Simon S, Davis L, Denyer M, Lockey R, Stack MJ, O'Connor MJ, Bishop K, Gough KC, Maddison BC, Thorne L, Spiropoulos J.

J Clin Microbiol. 2015 Aug;53(8):2593-604. doi: 10.1128/JCM.00508-15. Epub 2015 Jun 3.


The pathological and molecular but not clinical phenotypes are maintained after second passage of experimental atypical bovine spongiform encephalopathy in cattle.

Konold T, Phelan LJ, Clifford D, Chaplin MJ, Cawthraw S, Stack MJ, Simmons MM.

BMC Vet Res. 2014 Oct 2;10:243. doi: 10.1186/s12917-014-0243-2.


Overexpression of chimaeric murine/ovine PrP (A136H154Q171) in transgenic mice facilitates transmission and differentiation of ruminant prions.

Griffiths PC, Plater JM, Chave A, Jayasena D, Tout AC, Rice PB, Vickery CM, Spiropoulos J, Stack MJ, Windl O.

J Gen Virol. 2013 Nov;94(Pt 11):2577-86. doi: 10.1099/vir.0.051581-0. Epub 2013 Jun 12.


Unsuccessful oral transmission of scrapie from British sheep to cattle.

Konold T, Spiropoulos J, Chaplin MJ, Stack MJ, Hawkins SA, Wilesmith JW, Wells GA.

Vet Rec. 2013 Aug 3;173(5):118. doi: 10.1136/vr.101286. Epub 2013 May 30. No abstract available.


Four BSE cases with an L-BSE molecular profile in cattle from Great Britain.

Stack MJ, Chaplin MJ, Davis LA, Everitt S, Simmons MM, Windl O, Hope J, Burke P.

Vet Rec. 2013 Jan 19;172(3):70. doi: 10.1136/vr.101158. Epub 2012 Dec 18.


Bovine spongiform encephalopathy: the effect of oral exposure dose on attack rate and incubation period in cattle - an update.

Konold T, Arnold ME, Austin AR, Cawthraw S, Hawkins SA, Stack MJ, Simmons MM, Sayers AR, Dawson M, Wilesmith JW, Wells GA.

BMC Res Notes. 2012 Dec 5;5:674. doi: 10.1186/1756-0500-5-674.


Minimal involvement of the circumventricular organs in the pathogenesis of spontaneously arising and experimentally induced classical bovine spongiform encephalopathy.

Sisó S, Martin S, Konold T, Hawkins SA, Thurston L, Simmons MM, Stack MJ, Jeffrey M, González L.

J Comp Pathol. 2012 Aug-Oct;147(2-3):305-15. doi: 10.1016/j.jcpa.2012.01.008. Epub 2012 Apr 18.


Experimental H-type and L-type bovine spongiform encephalopathy in cattle: observation of two clinical syndromes and diagnostic challenges.

Konold T, Bone GE, Clifford D, Chaplin MJ, Cawthraw S, Stack MJ, Simmons MM.

BMC Vet Res. 2012 Mar 8;8:22. doi: 10.1186/1746-6148-8-22.


Studies of the transmissibility of the agent of bovine spongiform encephalopathy to the domestic chicken.

Moore J, Hawkins SA, Austin AR, Konold T, Green RB, Blamire IW, Dexter I, Stack MJ, Chaplin MJ, Langeveld JP, Simmons MM, Spencer YI, Webb PR, Dawson M, Wells GA.

BMC Res Notes. 2011 Nov 17;4:501. doi: 10.1186/1756-0500-4-501.


Detection and localisation of PrP(Sc) in the liver of sheep infected with scrapie and bovine spongiform encephalopathy.

Everest SJ, Ramsay AM, Chaplin MJ, Everitt S, Stack MJ, Neale MH, Jeffrey M, Moore SJ, Bellworthy SJ, Terry LA.

PLoS One. 2011 May 12;6(5):e19737. doi: 10.1371/journal.pone.0019737.


Experimental bovine spongiform encephalopathy: detection of PrP(Sc) in the small intestine relative to exposure dose and age.

Stack MJ, Moore SJ, Vidal-Diez A, Arnold ME, Jones EM, Spencer YI, Webb P, Spiropoulos J, Powell L, Bellerby P, Thurston L, Cooper J, Chaplin MJ, Davis LA, Everitt S, Focosi-Snyman R, Hawkins SA, Simmons MM, Wells GA.

J Comp Pathol. 2011 Aug-Oct;145(2-3):289-301. doi: 10.1016/j.jcpa.2011.01.010. Epub 2011 Mar 8.


Bovine spongiform encephalopathy: investigation of phenotypic variation among passive surveillance cases.

Stack MJ, Moore SJ, Davis A, Webb PR, Bradshaw JM, Lee YH, Chaplin M, Focosi-Snyman R, Thurston L, Spencer YI, Hawkins SA, Arnold ME, Simmons MM, Wells GA.

J Comp Pathol. 2011 May;144(4):277-88. doi: 10.1016/j.jcpa.2010.10.007. Epub 2010 Dec 9.


Relationship between clinical signs and postmortem test status in cattle experimentally infected with the bovine spongiform encephalopathy agent.

Konold T, Sayers AR, Sach A, Bone GE, van Winden S, Wells GA, Simmons MM, Stack MJ, Wear A, Hawkins SA.

BMC Vet Res. 2010 Dec 9;6:53. doi: 10.1186/1746-6148-6-53.


Third atypical BSE case in Great Britain with an H-type molecular profile.

Stack MJ, Focosi-Snyman R, Cawthraw S, Davis L, Chaplin MJ, Burke PJ.

Vet Rec. 2009 Nov 14;165(20):605-6. No abstract available.


Immunohistochemical and biochemical characteristics of BSE and CWD in experimentally infected European red deer (Cervus elaphus elaphus).

Martin S, Jeffrey M, González L, Sisó S, Reid HW, Steele P, Dagleish MP, Stack MJ, Chaplin MJ, Balachandran A.

BMC Vet Res. 2009 Jul 27;5:26. doi: 10.1186/1746-6148-5-26.


The Thrsp null mouse (Thrsp(tm1cnm)) and diet-induced obesity.

Anderson GW, Zhu Q, Metkowski J, Stack MJ, Gopinath S, Mariash CN.

Mol Cell Endocrinol. 2009 Apr 10;302(1):99-107. doi: 10.1016/j.mce.2009.01.005. Epub 2009 Jan 20.


Bone marrow infectivity in cattle exposed to the bovine spongiform encephalopathy agent.

Sohn HJ, Lee YH, Green RB, Spencer YI, Hawkins SA, Stack MJ, Konold T, Wells GA, Matthews D, Cho IS, Joo YS.

Vet Rec. 2009 Feb 28;164(9):272-3. No abstract available.


Detection of pathologic prion protein in the olfactory bulb of natural and experimental bovine spongiform encephalopathy affected cattle in Great Britain.

Lee YH, Simmons MM, Hawkins SA, Spencer YI, Webb P, Stack MJ, Wells GA.

Vet Pathol. 2009 Jan;46(1):59-62. doi: 10.1354/vp.46-1-59.


Poxviral disease in red squirrels Sciurus vulgaris in the UK: spatial and temporal trends of an emerging threat.

Sainsbury AW, Deaville R, Lawson B, Cooley WA, Farelly SS, Stack MJ, Duff P, McInnes CJ, Gurnell J, Russell PH, Rushton SP, Pfeiffer DU, Nettleton P, Lurz PW.

Ecohealth. 2008 Sep;5(3):305-16. doi: 10.1007/s10393-008-0191-z. Epub 2008 Oct 16.

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