Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 26

1.

Targeted and highly multiplexed detection of microorganisms by employing an ensemble of molecular probes.

Xu W, Krishnakumar S, Miranda M, Jensen MA, Fukushima M, Palm C, Fung E, Davis RW, St Onge RP, Hyman RW.

Appl Environ Microbiol. 2014 Jul;80(14):4153-61. doi: 10.1128/AEM.00666-14. Epub 2014 May 2.

PMID:
24795371
[PubMed - in process]
2.

Mapping the cellular response to small molecules using chemogenomic fitness signatures.

Lee AY, St Onge RP, Proctor MJ, Wallace IM, Nile AH, Spagnuolo PA, Jitkova Y, Gronda M, Wu Y, Kim MK, Cheung-Ong K, Torres NP, Spear ED, Han MK, Schlecht U, Suresh S, Duby G, Heisler LE, Surendra A, Fung E, Urbanus ML, Gebbia M, Lissina E, Miranda M, Chiang JH, Aparicio AM, Zeghouf M, Davis RW, Cherfils J, Boutry M, Kaiser CA, Cummins CL, Trimble WS, Brown GW, Schimmer AD, Bankaitis VA, Nislow C, Bader GD, Giaever G.

Science. 2014 Apr 11;344(6180):208-11. doi: 10.1126/science.1250217. Erratum in: Science. 2014 May 23;344(6186):1255771.

PMID:
24723613
[PubMed - indexed for MEDLINE]
3.

A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system.

Schlecht U, Suresh S, Xu W, Aparicio AM, Chu A, Proctor MJ, Davis RW, Scharfe C, St Onge RP.

BMC Genomics. 2014 Apr 5;15:263. doi: 10.1186/1471-2164-15-263.

PMID:
24708151
[PubMed - in process]
Free PMC Article
4.

PITPs as targets for selectively interfering with phosphoinositide signaling in cells.

Nile AH, Tripathi A, Yuan P, Mousley CJ, Suresh S, Wallace IM, Shah SD, Pohlhaus DT, Temple B, Nislow C, Giaever G, Tropsha A, Davis RW, St Onge RP, Bankaitis VA.

Nat Chem Biol. 2014 Jan;10(1):76-84. doi: 10.1038/nchembio.1389. Epub 2013 Nov 24.

PMID:
24292071
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cationic amphiphilic drugs are potent inhibitors of yeast sporulation.

Schlecht U, St Onge RP, Walther T, François JM, Davis RW.

PLoS One. 2012;7(8):e42853. doi: 10.1371/journal.pone.0042853. Epub 2012 Aug 8.

PMID:
22905177
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Multiplex assay for condition-dependent changes in protein-protein interactions.

Schlecht U, Miranda M, Suresh S, Davis RW, St Onge RP.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9213-8. doi: 10.1073/pnas.1204952109. Epub 2012 May 21.

PMID:
22615397
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Molecular probe technology detects bacteria without culture.

Hyman RW, St Onge RP, Kim H, Tamaresis JS, Miranda M, Aparicio AM, Fukushima M, Pourmand N, Giudice LC, Davis RW.

BMC Microbiol. 2012 Mar 9;12:29. doi: 10.1186/1471-2180-12-29.

PMID:
22404909
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Compound prioritization methods increase rates of chemical probe discovery in model organisms.

Wallace IM, Urbanus ML, Luciani GM, Burns AR, Han MK, Wang H, Arora K, Heisler LE, Proctor M, St Onge RP, Roemer T, Roy PJ, Cummins CL, Bader GD, Nislow C, Giaever G.

Chem Biol. 2011 Oct 28;18(10):1273-83. doi: 10.1016/j.chembiol.2011.07.018.

PMID:
22035796
[PubMed - indexed for MEDLINE]
Free Article
9.

A yeast-based assay identifies drugs active against human mitochondrial disorders.

Couplan E, Aiyar RS, Kucharczyk R, Kabala A, Ezkurdia N, Gagneur J, St Onge RP, Salin B, Soubigou F, Le Cann M, Steinmetz LM, di Rago JP, Blondel M.

Proc Natl Acad Sci U S A. 2011 Jul 19;108(29):11989-94. doi: 10.1073/pnas.1101478108. Epub 2011 Jun 29.

PMID:
21715656
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae.

Tamble CM, St Onge RP, Giaever G, Nislow C, Williams AG, Stuart JM, Lokey RS.

Mol Biosyst. 2011 Jun;7(6):2019-30. doi: 10.1039/c0mb00298d. Epub 2011 Apr 12.

PMID:
21487606
[PubMed - indexed for MEDLINE]
11.

Knocking out multigene redundancies via cycles of sexual assortment and fluorescence selection.

Suzuki Y, St Onge RP, Mani R, King OD, Heilbut A, Labunskyy VM, Chen W, Pham L, Zhang LV, Tong AH, Nislow C, Giaever G, Gladyshev VN, Vidal M, Schow P, Lehár J, Roth FP.

Nat Methods. 2011 Feb;8(2):159-64. doi: 10.1038/nmeth.1550. Epub 2011 Jan 9.

PMID:
21217751
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Gene annotation and drug target discovery in Candida albicans with a tagged transposon mutant collection.

Oh J, Fung E, Schlecht U, Davis RW, Giaever G, St Onge RP, Deutschbauer A, Nislow C.

PLoS Pathog. 2010 Oct 7;6(10):e1001140. doi: 10.1371/journal.ppat.1001140.

PMID:
20949076
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Exploring gene function and drug action using chemogenomic dosage assays.

Ericson E, Hoon S, St Onge RP, Giaever G, Nislow C.

Methods Enzymol. 2010;470:233-55. doi: 10.1016/S0076-6879(10)70010-0. Epub 2010 Mar 1.

PMID:
20946813
[PubMed - indexed for MEDLINE]
14.

Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples.

Smith AM, Heisler LE, St Onge RP, Farias-Hesson E, Wallace IM, Bodeau J, Harris AN, Perry KM, Giaever G, Pourmand N, Nislow C.

Nucleic Acids Res. 2010 Jul;38(13):e142. doi: 10.1093/nar/gkq368. Epub 2010 May 11.

PMID:
20460461
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Multiplex identification of microbes.

Hyman RW, St Onge RP, Allen EA, Miranda M, Aparicio AM, Fukushima M, Davis RW.

Appl Environ Microbiol. 2010 Jun;76(12):3904-10. doi: 10.1128/AEM.02785-09. Epub 2010 Apr 23.

PMID:
20418427
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The genetic landscape of a cell.

Costanzo M, Baryshnikova A, Bellay J, Kim Y, Spear ED, Sevier CS, Ding H, Koh JL, Toufighi K, Mostafavi S, Prinz J, St Onge RP, VanderSluis B, Makhnevych T, Vizeacoumar FJ, Alizadeh S, Bahr S, Brost RL, Chen Y, Cokol M, Deshpande R, Li Z, Lin ZY, Liang W, Marback M, Paw J, San Luis BJ, Shuteriqi E, Tong AH, van Dyk N, Wallace IM, Whitney JA, Weirauch MT, Zhong G, Zhu H, Houry WA, Brudno M, Ragibizadeh S, Papp B, Pál C, Roth FP, Giaever G, Nislow C, Troyanskaya OG, Bussey H, Bader GD, Gingras AC, Morris QD, Kim PM, Kaiser CA, Myers CL, Andrews BJ, Boone C.

Science. 2010 Jan 22;327(5964):425-31. doi: 10.1126/science.1180823.

PMID:
20093466
[PubMed - indexed for MEDLINE]
Free Article
17.

Yeast chemical genomics and drug discovery: an update.

Hoon S, St Onge RP, Giaever G, Nislow C.

Trends Pharmacol Sci. 2008 Oct;29(10):499-504. doi: 10.1016/j.tips.2008.07.006. Epub 2008 Aug 26. Review.

PMID:
18755517
[PubMed - indexed for MEDLINE]
18.

An integrated platform of genomic assays reveals small-molecule bioactivities.

Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C.

Nat Chem Biol. 2008 Aug;4(8):498-506. doi: 10.1038/nchembio.100. Epub 2008 Jul 11. Erratum in: Nat Chem Biol.2008 Oct;4(10):632.. StOnge, Robert P [corrected to St Onge,Robert P].

PMID:
18622389
[PubMed - indexed for MEDLINE]
19.

The chemical genomic portrait of yeast: uncovering a phenotype for all genes.

Hillenmeyer ME, Fung E, Wildenhain J, Pierce SE, Hoon S, Lee W, Proctor M, St Onge RP, Tyers M, Koller D, Altman RB, Davis RW, Nislow C, Giaever G.

Science. 2008 Apr 18;320(5874):362-5. doi: 10.1126/science.1150021.

PMID:
18420932
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Defining genetic interaction.

Mani R, St Onge RP, Hartman JL 4th, Giaever G, Roth FP.

Proc Natl Acad Sci U S A. 2008 Mar 4;105(9):3461-6. doi: 10.1073/pnas.0712255105. Epub 2008 Feb 27.

PMID:
18305163
[PubMed - indexed for MEDLINE]
Free PMC Article

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Loading ...
Write to the Help Desk