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A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195.

Eigl BJ, North S, Winquist E, Finch D, Wood L, Sridhar SS, Powers J, Good J, Sharma M, Squire JA, Bazov J, Jamaspishvili T, Cox ME, Bradbury PA, Eisenhauer EA, Chi KN.

Invest New Drugs. 2015 Aug;33(4):969-76. doi: 10.1007/s10637-015-0252-4. Epub 2015 May 19.


Understanding the emergence of ebola virus disease in sierra leone: stalking the virus in the threatening wake of emergence.

Wauquier N, Bangura J, Moses L, Humarr Khan S, Coomber M, Lungay V, Gbakie M, Sesay MS, Gassama IA, Massally JL, Gbakima A, Squire J, Lamin M, Kanneh L, Yillah M, Kargbo K, Roberts W, Vandi M, Kargbo D, Vincent T, Jambai A, Guttieri M, Fair J, Souris M, Gonzalez JP.

PLoS Curr. 2015 Apr 20;7. pii: ecurrents.outbreaks.9a6530ab7bb9096b34143230ab01cdef. doi: 10.1371/currents.outbreaks.9a6530ab7bb9096b34143230ab01cdef.


A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer.

Troyer DA, Jamaspishvili T, Wei W, Feng Z, Good J, Hawley S, Fazli L, McKenney JK, Simko J, Hurtado-Coll A, Carroll PR, Gleave M, Lance R, Lin DW, Nelson PS, Thompson IM, True LD, Brooks JD, Squire JA.

Prostate. 2015 Aug 1;75(11):1206-15. doi: 10.1002/pros.23003. Epub 2015 May 4.


A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer.

Koti M, Siu A, Clément I, Bidarimath M, Turashvili G, Edwards A, Rahimi K, Masson AM, Squire JA.

Br J Cancer. 2015 Mar 31;112(7):1215-22. doi: 10.1038/bjc.2015.81.


Statistical simulation of the magnetorotational dynamo.

Squire J, Bhattacharjee A.

Phys Rev Lett. 2015 Feb 27;114(8):085002. Epub 2015 Feb 26.


ERG/AKR1C3/AR Constitutes a Feed-Forward Loop for AR Signaling in Prostate Cancer Cells.

Powell K, Semaan L, Conley-LaComb MK, Asangani I, Wu YM, Ginsburg KB, Williams J, Squire JA, Maddipati KR, Cher ML, Chinni SR.

Clin Cancer Res. 2015 Jun 1;21(11):2569-79. doi: 10.1158/1078-0432.CCR-14-2352. Epub 2015 Mar 9.


Phase II study of PX-866 in recurrent glioblastoma.

Pitz MW, Eisenhauer EA, MacNeil MV, Thiessen B, Easaw JC, Macdonald DR, Eisenstat DD, Kakumanu AS, Salim M, Chalchal H, Squire J, Tsao MS, Kamel-Reid S, Banerji S, Tu D, Powers J, Hausman DF, Mason WP.

Neuro Oncol. 2015 Sep;17(9):1270-4. doi: 10.1093/neuonc/nou365. Epub 2015 Jan 20.


Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity.

Meyer M, Reimand J, Lan X, Head R, Zhu X, Kushida M, Bayani J, Pressey JC, Lionel AC, Clarke ID, Cusimano M, Squire JA, Scherer SW, Bernstein M, Woodin MA, Bader GD, Dirks PB.

Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):851-6. doi: 10.1073/pnas.1320611111. Epub 2015 Jan 5.


TickBot: a novel robotic device for controlling tick populations in the natural environment.

Gaff HD, White A, Leas K, Kelman P, Squire JC, Livingston DL, Sullivan GA, Baker EW, Sonenshine DE.

Ticks Tick Borne Dis. 2015 Mar;6(2):146-51. doi: 10.1016/j.ttbdis.2014.11.004. Epub 2014 Dec 12.


The intriguing dual lattices of the Myosin filaments in vertebrate striated muscles: evolution and advantage.

Luther PK, Squire JM.

Biology (Basel). 2014 Dec 3;3(4):846-65. doi: 10.3390/biology3040846. Review.


Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study.

Lalonde E, Ishkanian AS, Sykes J, Fraser M, Ross-Adams H, Erho N, Dunning MJ, Halim S, Lamb AD, Moon NC, Zafarana G, Warren AY, Meng X, Thoms J, Grzadkowski MR, Berlin A, Have CL, Ramnarine VR, Yao CQ, Malloff CA, Lam LL, Xie H, Harding NJ, Mak DY, Chu KC, Chong LC, Sendorek DH, P'ng C, Collins CC, Squire JA, Jurisica I, Cooper C, Eeles R, Pintilie M, Dal Pra A, Davicioni E, Lam WL, Milosevic M, Neal DE, van der Kwast T, Boutros PC, Bristow RG.

Lancet Oncol. 2014 Dec;15(13):1521-32. doi: 10.1016/S1470-2045(14)71021-6. Epub 2014 Nov 13.


Recurrent copy number alterations in prostate cancer: an in silico meta-analysis of publicly available genomic data.

Williams JL, Greer PA, Squire JA.

Cancer Genet. 2014 Oct-Dec;207(10-12):474-88. doi: 10.1016/j.cancergen.2014.09.003. Epub 2014 Sep 16.


Composite mantle cell and primary cutaneous anaplastic large cell lymphoma: case report and review of the literature.

Leduc C, Blandino II, Alhejaily A, Baetz T, Good DJ, Farmer PL, Squire JA, LeBrun DP.

Am J Dermatopathol. 2015 Mar;37(3):232-6. doi: 10.1097/DAD.0000000000000233.


Smoking-induced chromosomal segregation anomalies identified by FISH analysis of sperm.

Pereira CS, Juchniuk de Vozzi MS, Dos Santos SA, Vasconcelos MA, de Paz CC, Squire JA, Martelli L.

Mol Cytogenet. 2014 Sep 12;7(1):58. doi: 10.1186/s13039-014-0058-7. eCollection 2014.


Nonmodal growth of the magnetorotational instability.

Squire J, Bhattacharjee A.

Phys Rev Lett. 2014 Jul 11;113(2):025006. Epub 2014 Jul 10.


PTEN loss is associated with upgrading of prostate cancer from biopsy to radical prostatectomy.

Lotan TL, Carvalho FL, Peskoe SB, Hicks JL, Good J, Fedor HL, Humphreys E, Han M, Platz EA, Squire JA, De Marzo AM, Berman DM.

Mod Pathol. 2015 Jan;28(1):128-37. doi: 10.1038/modpathol.2014.85. Epub 2014 Jul 4.


Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.

Martin JW, Chilton-MacNeill S, Koti M, van Wijnen AJ, Squire JA, Zielenska M.

PLoS One. 2014 May 16;9(5):e95843. doi: 10.1371/journal.pone.0095843. eCollection 2014.


Resolution of the three dimensional structure of components of the glomerular filtration barrier.

Arkill KP, Qvortrup K, Starborg T, Mantell JM, Knupp C, Michel CC, Harper SJ, Salmon AH, Squire JM, Bates DO, Neal CR.

BMC Nephrol. 2014 Feb 1;15:24. doi: 10.1186/1471-2369-15-24.


Identification of the IGF1/PI3K/NF κB/ERK gene signalling networks associated with chemotherapy resistance and treatment response in high-grade serous epithelial ovarian cancer.

Koti M, Gooding RJ, Nuin P, Haslehurst A, Crane C, Weberpals J, Childs T, Bryson P, Dharsee M, Evans K, Feilotter HE, Park PC, Squire JA.

BMC Cancer. 2013 Nov 16;13:549. doi: 10.1186/1471-2407-13-549.


TMPRSS2-ERG status is not prognostic following prostate cancer radiotherapy: implications for fusion status and DSB repair.

Dal Pra A, Lalonde E, Sykes J, Warde F, Ishkanian A, Meng A, Maloff C, Srigley J, Joshua AM, Petrovics G, van der Kwast T, Evans A, Milosevic M, Saad F, Collins C, Squire J, Lam W, Bismar TA, Boutros PC, Bristow RG.

Clin Cancer Res. 2013 Sep 15;19(18):5202-9. doi: 10.1158/1078-0432.CCR-13-1049. Epub 2013 Aug 5.

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