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J Clin Rheumatol. 2011 Jan;17(1):35-6. doi: 10.1097/RHU.0b013e3182051928.

Squamous cell carcinomas arising in discoid lupus erythematosus scars: unusual occurrence in an African-American and in a sun-protected area.

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  • 1Philadelphia VA Medical Center; and Department of Dermatology, Hospital of the University of Pennsylvania, 3400 Civic Center Blvd., Philadelphia, PA 19104, USA.


Squamous cell carcinoma is a known and rare complication of long-standing discoid lupus erythematosus. Most cases have been reported in sun-exposed skin of whites. We report 2 unusual cases of squamous cell carcinoma arising in discoid lupus erythematosus scars: one in a sun-protected area of a white patient and a second in an African-American patient.

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