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Items: 1 to 20 of 116

1.

A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial.

Spears M, Lyttle N, D'Costa A, Chen BE, Yao CQ, Boutros PC, Burnell M, Levine MN, O'Brien P, Shepherd L, Bartlett JM.

Oncotarget. 2016 Apr 1. doi: 10.18632/oncotarget.8542. [Epub ahead of print]

2.

Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer.

Braunstein M, Liao L, Lyttle N, Lobo N, Taylor KJ, Krzyzanowski PM, Kalatskaya I, Yao CQ, Stein LD, Boutros PC, Twelves CJ, Marcellus R, Bartlett JM, Spears M.

Breast Cancer Res. 2016 Feb 6;18(1):16. doi: 10.1186/s13058-016-0676-6.

3.

Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.

James ND, Sydes MR, Clarke NW, Mason MD, Dearnaley DP, Spears MR, Ritchie AW, Parker CC, Russell JM, Attard G, de Bono J, Cross W, Jones RJ, Thalmann G, Amos C, Matheson D, Millman R, Alzouebi M, Beesley S, Birtle AJ, Brock S, Cathomas R, Chakraborti P, Chowdhury S, Cook A, Elliott T, Gale J, Gibbs S, Graham JD, Hetherington J, Hughes R, Laing R, McKinna F, McLaren DB, O'Sullivan JM, Parikh O, Peedell C, Protheroe A, Robinson AJ, Srihari N, Srinivasan R, Staffurth J, Sundar S, Tolan S, Tsang D, Wagstaff J, Parmar MK; STAMPEDE investigators.

Lancet. 2016 Mar 19;387(10024):1163-77. doi: 10.1016/S0140-6736(15)01037-5. Epub 2015 Dec 21.

4.

Failure-Free Survival and Radiotherapy in Patients With Newly Diagnosed Nonmetastatic Prostate Cancer: Data From Patients in the Control Arm of the STAMPEDE Trial.

James ND, Spears MR, Clarke NW, Dearnaley DP, Mason MD, Parker CC, Ritchie AW, Russell JM, Schiavone F, Attard G, de Bono JS, Birtle A, Engeler DS, Elliott T, Matheson D, O'Sullivan J, Pudney D, Srihari N, Wallace J, Barber J, Syndikus I, Parmar MK, Sydes MR; STAMPEDE Investigators.

JAMA Oncol. 2016 Mar 1;2(3):348-57. doi: 10.1001/jamaoncol.2015.4350.

5.

A four gene signature predicts benefit from anthracyclines: evidence from the BR9601 and MA.5 clinical trials.

Spears M, Yousif F, Lyttle N, Boutros PC, Munro AF, Twelves C, Pritchard KI, Levine MN, Shepherd L, Bartlett JM.

Oncotarget. 2015 Oct 13;6(31):31693-701. doi: 10.18632/oncotarget.5562.

6.

Effectiveness of bronchial thermoplasty in severe asthma in 'real life' patients compared with those recruited to clinical trials in the same centre.

Bicknell S, Chaudhuri R, Lee N, Shepherd M, Spears M, Pitman N, Cameron E, Cowan D, Nixon J, Thompson J, McSharry C, Thomson NC.

Ther Adv Respir Dis. 2015 Dec;9(6):267-71. doi: 10.1177/1753465815601332. Epub 2015 Aug 24.

PMID:
26307767
7.

Morphologic and cytogenetic variables affect the flow cytometric recovery of plasma cell myeloma cells in bone marrow aspirates.

Cogbill CH, Spears MD, Vantuinen P, Harrington AM, Olteanu H, Kroft SH.

Int J Lab Hematol. 2015 Dec;37(6):797-808. doi: 10.1111/ijlh.12411. Epub 2015 Jul 30.

PMID:
26224420
8.

Serum periostin in smokers and never smokers with asthma.

Thomson NC, Chaudhuri R, Spears M, Haughney J, McSharry C.

Respir Med. 2015 Jun;109(6):708-15. doi: 10.1016/j.rmed.2015.03.009. Epub 2015 Apr 3.

PMID:
25869478
9.

Ultrasoft, highly deformable microgels.

Bachman H, Brown AC, Clarke KC, Dhada KS, Douglas A, Hansen CE, Herman E, Hyatt JS, Kodlekere P, Meng Z, Saxena S, Spears MW Jr, Welsch N, Lyon LA.

Soft Matter. 2015 Mar 14;11(10):2018-28. doi: 10.1039/c5sm00047e.

PMID:
25648590
10.

Results of the California Healthy Homes Indoor Air Quality Study of 2011-2013: impact of natural gas appliances on air pollutant concentrations.

Mullen NA, Li J, Russell ML, Spears M, Less BD, Singer BC.

Indoor Air. 2016 Apr;26(2):231-45. doi: 10.1111/ina.12190. Epub 2015 Mar 17.

PMID:
25647016
11.

Clinical validation of targeted next-generation sequencing for inherited disorders.

Yohe S, Hauge A, Bunjer K, Kemmer T, Bower M, Schomaker M, Onsongo G, Wilson J, Erdmann J, Zhou Y, Deshpande A, Spears MD, Beckman K, Silverstein KA, Thyagarajan B.

Arch Pathol Lab Med. 2015 Feb;139(2):204-10. doi: 10.5858/arpa.2013-0625-OA.

PMID:
25611102
12.

Atorvastatin in combination with inhaled beclometasone modulates inflammatory sputum mediators in smokers with asthma.

Thomson NC, Charron CE, Chaudhuri R, Spears M, Ito K, McSharry C.

Pulm Pharmacol Ther. 2015 Apr;31:1-8. doi: 10.1016/j.pupt.2015.01.001. Epub 2015 Jan 14.

PMID:
25595138
13.

Poor symptom control is associated with reduced CT scan segmental airway lumen area in smokers with asthma.

Thomson NC, Chaudhuri R, Spears M, Messow CM, MacNee W, Connell M, Murchison JT, Sproule M, McSharry C.

Chest. 2015 Mar;147(3):735-44. doi: 10.1378/chest.14-1119. Erratum in: Chest. 2015 Aug;148(2):572.

PMID:
25356950
14.

Molecular characterisation of isogenic taxane resistant cell lines identify novel drivers of drug resistance.

Kenicer J, Spears M, Lyttle N, Taylor KJ, Liao L, Cunningham CA, Lambros M, MacKay A, Yao C, Reis-Filho J, Bartlett JM.

BMC Cancer. 2014 Oct 14;14:762. doi: 10.1186/1471-2407-14-762.

15.

Survival with Newly Diagnosed Metastatic Prostate Cancer in the "Docetaxel Era": Data from 917 Patients in the Control Arm of the STAMPEDE Trial (MRC PR08, CRUK/06/019).

James ND, Spears MR, Clarke NW, Dearnaley DP, De Bono JS, Gale J, Hetherington J, Hoskin PJ, Jones RJ, Laing R, Lester JF, McLaren D, Parker CC, Parmar MK, Ritchie AW, Russell JM, Strebel RT, Thalmann GN, Mason MD, Sydes MR.

Eur Urol. 2015 Jun;67(6):1028-38. doi: 10.1016/j.eururo.2014.09.032. Epub 2014 Oct 6.

16.

Increased sputum endotoxin levels are associated with an impaired lung function response to oral steroids in asthmatic patients.

McSharry C, Spears M, Chaudhuri R, Cameron EJ, Husi H, Thomson NC.

J Allergy Clin Immunol. 2014 Nov;134(5):1068-75. doi: 10.1016/j.jaci.2014.08.022. Epub 2014 Sep 26.

PMID:
25262463
17.

EBV-positive mucocutaneous ulcer in organ transplant recipients: a localized indolent posttransplant lymphoproliferative disorder.

Hart M, Thakral B, Yohe S, Balfour HH Jr, Singh C, Spears M, McKenna RW.

Am J Surg Pathol. 2014 Nov;38(11):1522-9. doi: 10.1097/PAS.0000000000000282.

PMID:
25007145
18.

Low sputum MMP-9/TIMP ratio is associated with airway narrowing in smokers with asthma.

Chaudhuri R, McSharry C, Brady J, Grierson C, Messow CM, Spears M, Miele G, Nocka K, MacNee W, Connell M, Murchison JT, Sproule M, Hilmi OJ, Miller DK, Thomson NC.

Eur Respir J. 2014 Oct;44(4):895-904. doi: 10.1183/09031936.00047014. Epub 2014 Jul 3.

19.

Combining enzalutamide with abiraterone, prednisone, and androgen deprivation therapy in the STAMPEDE trial.

Attard G, Sydes MR, Mason MD, Clarke NW, Aebersold D, de Bono JS, Dearnaley DP, Parker CC, Ritchie AW, Russell JM, Thalmann G, Cassoly E, Millman R, Matheson D, Schiavone F, Spears MR, Parmar MK, James ND.

Eur Urol. 2014 Nov;66(5):799-802. doi: 10.1016/j.eururo.2014.05.038. Epub 2014 Jun 27.

20.

Tunable swelling and rolling of microgel membranes.

Zhang L, Spears MW Jr, Lyon LA.

Langmuir. 2014 Jul 8;30(26):7628-34. doi: 10.1021/la500860t. Epub 2014 Jun 26.

PMID:
24927510
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