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Results: 13

1.

Organocatalytic atroposelective aldol condensation: synthesis of axially chiral biaryls by arene formation.

Link A, Sparr C.

Angew Chem Int Ed Engl. 2014 May 19;53(21):5458-61. doi: 10.1002/anie.201402441. Epub 2014 Apr 23.

PMID:
24757165
[PubMed - in process]
2.

Syntheses, receptor bindings, in vitro and in vivo stabilities and biodistributions of DOTA-neurotensin(8-13) derivatives containing β-amino acid residues - a lesson about the importance of animal experiments.

Sparr C, Purkayastha N, Yoshinari T, Seebach D, Maschauer S, Prante O, Hübner H, Gmeiner P, Kolesinska B, Cescato R, Waser B, Reubi JC.

Chem Biodivers. 2013 Dec;10(12):2101-21. doi: 10.1002/cbdv.201300331.

PMID:
24327436
[PubMed - in process]
3.

Improved efficacy of fosmidomycin against Plasmodium and Mycobacterium species by combination with the cell-penetrating peptide octaarginine.

Sparr C, Purkayastha N, Kolesinska B, Gengenbacher M, Amulic B, Matuschewski K, Seebach D, Kamena F.

Antimicrob Agents Chemother. 2013 Oct;57(10):4689-98. doi: 10.1128/AAC.00427-13. Epub 2013 Jul 15.

PMID:
23856773
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Synthesis of enantiomerically enriched 3-amino-2-oxindoles through a palladium-mediated asymmetric intramolecular arylation of α-ketimino amides.

Tolstoy P, Lee SX, Sparr C, Ley SV.

Org Lett. 2012 Sep 21;14(18):4810-3. Epub 2012 Sep 4.

PMID:
22946713
[PubMed - indexed for MEDLINE]
5.

The surfactant protein C mutation A116D alters cellular processing, stress tolerance, surfactant lipid composition, and immune cell activation.

Zarbock R, Woischnik M, Sparr C, Thurm T, Kern S, Kaltenborn E, Hector A, Hartl D, Liebisch G, Schmitz G, Griese M.

BMC Pulm Med. 2012 Mar 29;12:15. doi: 10.1186/1471-2466-12-15.

PMID:
22458263
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Fluorine conformational effects in organocatalysis: an emerging strategy for molecular design.

Zimmer LE, Sparr C, Gilmour R.

Angew Chem Int Ed Engl. 2011 Dec 9;50(50):11860-71. doi: 10.1002/anie.201102027. Epub 2011 Sep 26. Review.

PMID:
21953782
[PubMed - indexed for MEDLINE]
7.

Cyclopropyl iminium activation: reactivity umpolung in enantioselective organocatalytic reaction design.

Sparr C, Gilmour R.

Angew Chem Int Ed Engl. 2011 Aug 29;50(36):8391-5. doi: 10.1002/anie.201103360. Epub 2011 Jul 22. No abstract available.

PMID:
21786377
[PubMed - indexed for MEDLINE]
8.

Theoretical and X-ray crystallographic evidence of a fluorine-imine gauche effect: an addendum to Dunathan's stereoelectronic hypothesis.

Sparr C, Salamanova E, Schweizer WB, Senn HM, Gilmour R.

Chemistry. 2011 Aug 1;17(32):8850-7. doi: 10.1002/chem.201100644. Epub 2011 Jul 5.

PMID:
21732444
[PubMed - indexed for MEDLINE]
9.

A non-BRICHOS surfactant protein c mutation disrupts epithelial cell function and intercellular signaling.

Woischnik M, Sparr C, Kern S, Thurm T, Hector A, Hartl D, Liebisch G, Mulugeta S, Beers MF, Schmitz G, Griese M.

BMC Cell Biol. 2010 Nov 20;11:88. doi: 10.1186/1471-2121-11-88.

PMID:
21092132
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Fluoro-organocatalysts: conformer equivalents as a tool for mechanistic studies.

Sparr C, Gilmour R.

Angew Chem Int Ed Engl. 2010 Sep 3;49(37):6520-3. doi: 10.1002/anie.201003734. No abstract available.

PMID:
20677308
[PubMed]
11.

Fluorinated quinine alkaloids: synthesis, X-ray structure analysis and antimalarial parasite chemotherapy.

Bucher C, Sparr C, Schweizer WB, Gilmour R.

Chemistry. 2009 Aug 3;15(31):7637-47. doi: 10.1002/chem.200900505.

PMID:
19565586
[PubMed - indexed for MEDLINE]
12.

The fluorine-iminium ion gauche effect: proof of principle and application to asymmetric organocatalysis.

Sparr C, Schweizer WB, Senn HM, Gilmour R.

Angew Chem Int Ed Engl. 2009;48(17):3065-8. doi: 10.1002/anie.200900405.

PMID:
19322862
[PubMed - indexed for MEDLINE]
13.

Vincristine by continuous infusion in refractory breast cancer: a phase II study.

Hopkins JO, Jackson DV Jr, White DR, Muss HB, Richards F 2nd, Cooper MR, Stuart JJ, Sparr CL, Wells HB.

Am J Clin Oncol. 1983 Oct;6(5):529-32.

PMID:
6613919
[PubMed - indexed for MEDLINE]

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