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Items: 1 to 20 of 96

1.

Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro.

Moeckel S, Vollmann-Zwerenz A, Proescholdt M, Brawanski A, Riemenschneider MJ, Bogdahn U, Bosserhoff AK, Spang R, Hau P.

PLoS One. 2016 Mar 15;11(3):e0151312. doi: 10.1371/journal.pone.0151312. eCollection 2016.

2.

Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.

Pirkl M, Hand E, Kube D, Spang R.

Bioinformatics. 2015 Nov 17. pii: btv680. [Epub ahead of print]

3.

A statistical approach to virtual cellular experiments: improved causal discovery using accumulation IDA (aIDA).

Taruttis F, Spang R, Engelmann JC.

Bioinformatics. 2015 Dec 1;31(23):3807-14. doi: 10.1093/bioinformatics/btv461. Epub 2015 Aug 6.

4.

Clinical and pathological features of Burkitt lymphoma showing expression of BCL2--an analysis including gene expression in formalin-fixed paraffin-embedded tissue.

Masqué-Soler N, Szczepanowski M, Kohler CW, Aukema SM, Nagel I, Richter J, Siebert R, Spang R, Burkhardt B, Klapper W.

Br J Haematol. 2015 Nov;171(4):501-8. doi: 10.1111/bjh.13624. Epub 2015 Jul 27.

PMID:
26218299
5.

Low urinary indoxyl sulfate levels early after transplantation reflect a disrupted microbiome and are associated with poor outcome.

Weber D, Oefner PJ, Hiergeist A, Koestler J, Gessner A, Weber M, Hahn J, Wolff D, Stämmler F, Spang R, Herr W, Dettmer K, Holler E.

Blood. 2015 Oct 1;126(14):1723-8. doi: 10.1182/blood-2015-04-638858. Epub 2015 Jul 24.

PMID:
26209659
6.

Data Normalization of (1)H NMR Metabolite Fingerprinting Data Sets in the Presence of Unbalanced Metabolite Regulation.

Hochrein J, Zacharias HU, Taruttis F, Samol C, Engelmann JC, Spang R, Oefner PJ, Gronwald W.

J Proteome Res. 2015 Aug 7;14(8):3217-28. doi: 10.1021/acs.jproteome.5b00192. Epub 2015 Jul 22.

PMID:
26147738
7.

Causal Modeling of Cancer-Stromal Communication Identifies PAPPA as a Novel Stroma-Secreted Factor Activating NFκB Signaling in Hepatocellular Carcinoma.

Engelmann JC, Amann T, Ott-Rötzer B, Nützel M, Reinders Y, Reinders J, Thasler WE, Kristl T, Teufel A, Huber CG, Oefner PJ, Spang R, Hellerbrand C.

PLoS Comput Biol. 2015 May 28;11(5):e1004293. doi: 10.1371/journal.pcbi.1004293. eCollection 2015 May.

8.

Response-predictive gene expression profiling of glioma progenitor cells in vitro.

Moeckel S, Meyer K, Leukel P, Heudorfer F, Seliger C, Stangl C, Bogdahn U, Proescholdt M, Brawanski A, Vollmann-Zwerenz A, Riemenschneider MJ, Bosserhoff AK, Spang R, Hau P.

PLoS One. 2014 Sep 30;9(9):e108632. doi: 10.1371/journal.pone.0108632. eCollection 2014.

9.

ACGME Duty Hour Requirements: Perceptions and Impact on Resident Training and Patient Care.

Levine WN, Spang RC 3rd.

J Am Acad Orthop Surg. 2014 Sep;22(9):535-44. doi: 10.5435/JAAOS-22-09-535.

PMID:
25157035
10.

siPools: highly complex but accurately defined siRNA pools eliminate off-target effects.

Hannus M, Beitzinger M, Engelmann JC, Weickert MT, Spang R, Hannus S, Meister G.

Nucleic Acids Res. 2014 Jul;42(12):8049-61. doi: 10.1093/nar/gku480. Epub 2014 May 29.

11.

Increased expression of c-Jun in nonalcoholic fatty liver disease.

Dorn C, Engelmann JC, Saugspier M, Koch A, Hartmann A, Müller M, Spang R, Bosserhoff A, Hellerbrand C.

Lab Invest. 2014 Apr;94(4):394-408. doi: 10.1038/labinvest.2014.3. Epub 2014 Feb 3.

12.

Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease.

Holler E, Butzhammer P, Schmid K, Hundsrucker C, Koestler J, Peter K, Zhu W, Sporrer D, Hehlgans T, Kreutz M, Holler B, Wolff D, Edinger M, Andreesen R, Levine JE, Ferrara JL, Gessner A, Spang R, Oefner PJ.

Biol Blood Marrow Transplant. 2014 May;20(5):640-5. doi: 10.1016/j.bbmt.2014.01.030. Epub 2014 Jan 31.

13.

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, Lefebvre C, Lisfeld J, Löffler M, Macleod RA, Nagel I, Oschlies I, Rosolowski M, Russell RB, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphoma Network Project; Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group.

Blood. 2014 Feb 20;123(8):1187-98. doi: 10.1182/blood-2013-06-507996. Epub 2014 Jan 7.

14.

YBX1 is a modulator of MIA/CD-RAP-dependent chondrogenesis.

Schmid R, Meyer K, Spang R, Schittek B, Bosserhoff AK.

PLoS One. 2013 Dec 12;8(12):e82166. doi: 10.1371/journal.pone.0082166. eCollection 2013.

15.

Exact likelihood computation in Boolean networks with probabilistic time delays, and its application in signal network reconstruction.

Dümcke S, Bräuer J, Anchang B, Spang R, Beerenwinkel N, Tresch A.

Bioinformatics. 2014 Feb 1;30(3):414-9. doi: 10.1093/bioinformatics/btt696. Epub 2013 Nov 30.

16.

Considering unknown unknowns: reconstruction of nonconfoundable causal relations in biological networks.

Sadeh MJ, Moffa G, Spang R.

J Comput Biol. 2013 Nov;20(11):920-32. doi: 10.1089/cmb.2013.0119.

17.

Biological characterization of adult MYC-translocation-positive mature B-cell lymphomas other than molecular Burkitt lymphoma.

Aukema SM, Kreuz M, Kohler CW, Rosolowski M, Hasenclever D, Hummel M, Küppers R, Lenze D, Ott G, Pott C, Richter J, Rosenwald A, Szczepanowski M, Schwaenen C, Stein H, Trautmann H, Wessendorf S, Trümper L, Loeffler M, Spang R, Kluin PM, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project.

Haematologica. 2014 Apr;99(4):726-35. doi: 10.3324/haematol.2013.091827. Epub 2013 Oct 31.

18.

Wnt secretion is required to maintain high levels of Wnt activity in colon cancer cells.

Voloshanenko O, Erdmann G, Dubash TD, Augustin I, Metzig M, Moffa G, Hundsrucker C, Kerr G, Sandmann T, Anchang B, Demir K, Boehm C, Leible S, Ball CR, Glimm H, Spang R, Boutros M.

Nat Commun. 2013;4:2610. doi: 10.1038/ncomms3610.

19.

Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens.

Masqué-Soler N, Szczepanowski M, Kohler CW, Spang R, Klapper W.

Blood. 2013 Sep 12;122(11):1985-6. doi: 10.1182/blood-2013-06-508937. No abstract available.

20.

LMX1B is essential for the maintenance of differentiated podocytes in adult kidneys.

Burghardt T, Kastner J, Suleiman H, Rivera-Milla E, Stepanova N, Lottaz C, Kubitza M, Böger CA, Schmidt S, Gorski M, de Vries U, Schmidt H, Hertting I, Kopp J, Rascle A, Moser M, Heid IM, Warth R, Spang R, Wegener J, Mierke CT, Englert C, Witzgall R.

J Am Soc Nephrol. 2013 Nov;24(11):1830-48. doi: 10.1681/ASN.2012080788. Epub 2013 Aug 29.

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