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Results: 20

1.

The basics of preclinical drug development for neurodegenerative disease indications.

Steinmetz KL, Spack EG.

BMC Neurol. 2009 Jun 12;9 Suppl 1:S2. doi: 10.1186/1471-2377-9-S1-S2. Review.

PMID:
19534731
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Antigen-specific therapies for the treatment of multiple sclerosis: a clinical trial update.

Spack EG.

Expert Opin Investig Drugs. 1997 Nov;6(11):1715-27.

PMID:
15989576
[PubMed]
3.

T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis.

Klehmet J, Shive C, Guardia-Wolff R, Petersen I, Spack EG, Boehm BO, Weissert R, Forsthuber TG.

Clin Immunol. 2004 Apr;111(1):53-60.

PMID:
15093552
[PubMed - indexed for MEDLINE]
4.

Effects of monoclonal anti-PcrV antibody on Pseudomonas aeruginosa-induced acute lung injury in a rat model.

Faure K, Fujimoto J, Shimabukuro DW, Ajayi T, Shime N, Moriyama K, Spack EG, Wiener-Kronish JP, Sawa T.

J Immune Based Ther Vaccines. 2003 Aug 13;1(1):2.

PMID:
12943554
[PubMed - as supplied by publisher]
Free PMC Article
5.

The double-edged cytokine sword of non-viral gene targeting to tumors.

Spack EG, Sorgi FL.

Drug Discov Today. 2002 Jul 15;7(14):754-5. No abstract available.

PMID:
12547028
[PubMed - indexed for MEDLINE]
6.

Generation and characterization of a protective monoclonal antibody to Pseudomonas aeruginosa PcrV.

Frank DW, Vallis A, Wiener-Kronish JP, Roy-Burman A, Spack EG, Mullaney BP, Megdoud M, Marks JD, Fritz R, Sawa T.

J Infect Dis. 2002 Jul 1;186(1):64-73. Epub 2002 Jun 14.

PMID:
12089663
[PubMed - indexed for MEDLINE]
Free Article
7.

T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells.

Forsthuber TG, Shive CL, Wienhold W, de Graaf K, Spack EG, Sublett R, Melms A, Kort J, Racke MK, Weissert R.

J Immunol. 2001 Dec 15;167(12):7119-25.

PMID:
11739534
[PubMed - indexed for MEDLINE]
Free Article
8.

Therapeutic administration of anti-PcrV F(ab')(2) in sepsis associated with Pseudomonas aeruginosa.

Shime N, Sawa T, Fujimoto J, Faure K, Allmond LR, Karaca T, Swanson BL, Spack EG, Wiener-Kronish JP.

J Immunol. 2001 Nov 15;167(10):5880-6.

PMID:
11698464
[PubMed - indexed for MEDLINE]
Free Article
9.

Acetylcholine receptor peptide recognition in HLA DR3-transgenic mice: in vivo responses correlate with MHC-peptide binding.

Raju R, Spack EG, David CS.

J Immunol. 2001 Jul 15;167(2):1118-24.

PMID:
11441124
[PubMed - indexed for MEDLINE]
Free Article
10.

Developing non-viral DNA delivery systems for cancer and infectious disease.

Spack EG, Sorgi FL.

Drug Discov Today. 2001 Feb 1;6(4):186-197.

PMID:
11173266
[PubMed - as supplied by publisher]
11.

MHC-based diagnostics and therapeutics - clinical applications for disease-linked genes.

Howard MC, Spack EG, Choudhury K, Greten TF, Schneck JP.

Immunol Today. 1999 Apr;20(4):161-5. No abstract available.

PMID:
10203711
[PubMed - indexed for MEDLINE]
12.

Scanning a DRB3*0101 (DR52a)-restricted epitope cross-presented by DR3: overlapping natural and artificial determinants in the human acetylcholine receptor.

Nagvekar N, Corlett L, Jacobson LW, Matsuo H, Chalkley R, Driscoll PC, Deshpande S, Spack EG, Willcox N.

J Immunol. 1999 Apr 1;162(7):4079-87.

PMID:
10201931
[PubMed - indexed for MEDLINE]
Free Article
13.

Thymus, thymoma, and specific T cells in myasthenia gravis.

Beeson D, Bond AP, Corlett L, Curnow SJ, Hill ME, Jacobson LW, MacLennan C, Meager A, Moody AM, Moss P, Nagvekar N, Newsom-Davis J, Pantic N, Roxanis I, Spack EG, Vincent A, Willcox N.

Ann N Y Acad Sci. 1998 May 13;841:371-87. Review. No abstract available.

PMID:
9668262
[PubMed - indexed for MEDLINE]
14.

A sensitive ELISPOT assay to detect low-frequency human T lymphocytes.

McCutcheon M, Wehner N, Wensky A, Kushner M, Doan S, Hsiao L, Calabresi P, Ha T, Tran TV, Tate KM, Winkelhake J, Spack EG.

J Immunol Methods. 1997 Dec 29;210(2):149-66.

PMID:
9520298
[PubMed - indexed for MEDLINE]
15.

Treatment of autoimmune diseases through manipulation of antigen presentation.

Spack EG.

Crit Rev Immunol. 1997;17(5-6):529-36. Review.

PMID:
9419440
[PubMed - indexed for MEDLINE]
16.

Transfer technique for minimizing waste of sonified adjuvant emulsions.

Spack EG, Toavs D.

Biotechniques. 1996 Jan;20(1):28-30. No abstract available.

PMID:
8770399
[PubMed - indexed for MEDLINE]
17.

Induction of tolerance in experimental autoimmune myasthenia gravis with solubilized MHC class II:acetylcholine receptor peptide complexes.

Spack EG, McCutcheon M, Corbelletta N, Nag B, Passmore D, Sharma SD.

J Autoimmun. 1995 Dec;8(6):787-807.

PMID:
8824707
[PubMed - indexed for MEDLINE]
18.

Evidence that the mechanism of prenatal germ cell death in the mouse is apoptosis.

Coucouvanis EC, Sherwood SW, Carswell-Crumpton C, Spack EG, Jones PP.

Exp Cell Res. 1993 Dec;209(2):238-47.

PMID:
8262141
[PubMed - indexed for MEDLINE]
19.

Temporal order of DNA replication in the H-2 major histocompatibility complex of the mouse.

Spack EG, Lewis ED, Paradowski B, Schimke RT, Jones PP.

Mol Cell Biol. 1992 Nov;12(11):5174-88.

PMID:
1406689
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Hydrophobic adsorption chromatography to reduce nonspecific staining by rhodamine-labeled antibodies.

Spack EG Jr, Packard B, Wier ML, Edidin M.

Anal Biochem. 1986 Oct;158(1):233-7.

PMID:
2432803
[PubMed - indexed for MEDLINE]

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