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Results: 1 to 20 of 30

1.

Phosphate sink containing two-component signaling systems as tunable threshold devices.

Amin M, Kothamachu VB, Feliu E, Scharf BE, Porter SL, Soyer OS.

PLoS Comput Biol. 2014 Oct 30;10(10):e1003890. doi: 10.1371/journal.pcbi.1003890. eCollection 2014 Oct.

PMID:
25357192
[PubMed - in process]
Free PMC Article
2.

Bacterial drug tolerance under clinical conditions is governed by anaerobic adaptation but not anaerobic respiration.

Hemsley CM, Luo JX, Andreae CA, Butler CS, Soyer OS, Titball RW.

Antimicrob Agents Chemother. 2014 Oct;58(10):5775-83. doi: 10.1128/AAC.02793-14. Epub 2014 Jul 21.

PMID:
25049258
[PubMed - in process]
Free PMC Article
3.

Synthetic microbial communities.

Grosskopf T, Soyer OS.

Curr Opin Microbiol. 2014 Apr;18:72-7. doi: 10.1016/j.mib.2014.02.002. Epub 2014 Mar 14.

PMID:
24632350
[PubMed - in process]
Free PMC Article
4.

Phosphorelays provide tunable signal processing capabilities for the cell.

Kothamachu VB, Feliu E, Wiuf C, Cardelli L, Soyer OS.

PLoS Comput Biol. 2013;9(11):e1003322. doi: 10.1371/journal.pcbi.1003322. Epub 2013 Nov 7.

PMID:
24244132
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Systems and synthetic biology underpinning biotechnology.

Soyer OS, Swain PS.

Curr Opin Biotechnol. 2013 Aug;24(4):735-6. doi: 10.1016/j.copbio.2013.06.002. Epub 2013 Jun 27. No abstract available.

PMID:
23810372
[PubMed - indexed for MEDLINE]
6.

Evolutionary systems biology: what it is and why it matters.

Soyer OS, O'Malley MA.

Bioessays. 2013 Aug;35(8):696-705. doi: 10.1002/bies.201300029. Epub 2013 May 16. Review.

PMID:
23681824
[PubMed - indexed for MEDLINE]
7.

Metabolic tinker: an online tool for guiding the design of synthetic metabolic pathways.

McClymont K, Soyer OS.

Nucleic Acids Res. 2013 Jun;41(11):e113. doi: 10.1093/nar/gkt234. Epub 2013 Apr 10.

PMID:
23580552
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Split histidine kinases enable ultrasensitivity and bistability in two-component signaling networks.

Amin M, Porter SL, Soyer OS.

PLoS Comput Biol. 2013;9(3):e1002949. doi: 10.1371/journal.pcbi.1002949. Epub 2013 Mar 7.

PMID:
23505358
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Evolutionary principles underlying structure and response dynamics of cellular networks.

Steinacher A, Soyer OS.

Adv Exp Med Biol. 2012;751:225-47. doi: 10.1007/978-1-4614-3567-9_11. Review.

PMID:
22821461
[PubMed - indexed for MEDLINE]
10.

The roles of integration in molecular systems biology.

O'Malley MA, Soyer OS.

Stud Hist Philos Biol Biomed Sci. 2012 Mar;43(1):58-68. doi: 10.1016/j.shpsc.2011.10.006. Epub 2011 Nov 1.

PMID:
22326073
[PubMed - indexed for MEDLINE]
11.

Bistability in feedback circuits as a byproduct of evolution of evolvability.

Kuwahara H, Soyer OS.

Mol Syst Biol. 2012 Jan 17;8:564. doi: 10.1038/msb.2011.98.

PMID:
22252387
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Evolution of response dynamics underlying bacterial chemotaxis.

Soyer OS, Goldstein RA.

BMC Evol Biol. 2011 Aug 16;11:240. doi: 10.1186/1471-2148-11-240.

PMID:
21846396
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Evolution under fluctuating environments explains observed robustness in metabolic networks.

Soyer OS, Pfeiffer T.

PLoS Comput Biol. 2010 Aug 26;6(8). pii: e1000907. doi: 10.1371/journal.pcbi.1000907.

PMID:
20865149
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Duplicate retention in signalling proteins and constraints from network dynamics.

Soyer OS, Creevey CJ.

J Evol Biol. 2010 Nov;23(11):2410-21. doi: 10.1111/j.1420-9101.2010.02101.x. Epub 2010 Sep 6.

PMID:
20825548
[PubMed - indexed for MEDLINE]
15.

Response dynamics of phosphorelays suggest their potential utility in cell signalling.

Csikász-Nagy A, Cardelli L, Soyer OS.

J R Soc Interface. 2011 Apr 6;8(57):480-8. doi: 10.1098/rsif.2010.0336. Epub 2010 Aug 11.

PMID:
20702449
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The promise of evolutionary systems biology: lessons from bacterial chemotaxis.

Soyer OS.

Sci Signal. 2010 Jun 29;3(128):pe23. doi: 10.1126/scisignal.3128pe23.

PMID:
20587804
[PubMed - indexed for MEDLINE]
17.

Regulating the total level of a signaling protein can vary its dynamics in a range from switch like ultrasensitivity to adaptive responses.

Soyer OS, Kuwahara H, Csikász-Nagy A.

FEBS J. 2009 Jun;276(12):3290-8. doi: 10.1111/j.1742-4658.2009.07054.x. Epub 2009 May 5.

PMID:
19438711
[PubMed - indexed for MEDLINE]
18.

Parasites lead to evolution of robustness against gene loss in host signaling networks.

Salathé M, Soyer OS.

Mol Syst Biol. 2008;4:202. doi: 10.1038/msb.2008.44. Epub 2008 Jul 15.

PMID:
18628743
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Evolution of taxis responses in virtual bacteria: non-adaptive dynamics.

Goldstein RA, Soyer OS.

PLoS Comput Biol. 2008 May 23;4(5):e1000084. doi: 10.1371/journal.pcbi.1000084.

PMID:
18483577
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Adaptive dynamics with a single two-state protein.

Csikász-Nagy A, Soyer OS.

J R Soc Interface. 2008 Aug 6;5 Suppl 1:S41-7. doi: 10.1098/rsif.2008.0099.focus.

PMID:
18445552
[PubMed - indexed for MEDLINE]
Free PMC Article

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